HIV/AIDS, the neuropsychological symptoms of HIV infection, and effect of combination antiretroviral therapy on vocational rehabilitation.

Search Strategy

The strategy of the literature review searched four databases: Medline, EMBase, Web of Science, and PsychINFO. Together these databases access information related to medicine, nursing, health care delivery, psychiatry, sociology, and psychology. Search strategies were developed for each database using text terms and Medical Subject Headings focused on eight subject areas, including HIV/AIDS, disability, employment, quality of life, functional capacity, treatment outcomes, severity of impairment, and comorbidities. Distinct terms were identified in each subject area to yield as many unique results as possible. Strategy parameters included limiting the search to human subjects, the English language, and studies published from 2004 to 2009. This time period was chosen to focus the studies on the most recent medical and scientific literature.

Preliminary Analysis and Results

A rigorous review of titles and abstracts determined which studies met the inclusion criteria. Each study was coded according to the category system. The preliminary results include 32 Category 1 articles, which focus on study populations with HIV/AIDS and employment capability. Table D-1 provides a detailed review of all Category 1 studies. An additional 331 articles were identified as Category 2 articles, which inform broader parameters potentially affecting functional capacity of populations with HIV/AIDS. These parameters include relative quality of life (with specific measurements for health-related quality of life), comorbid conditions, gender comparisons, and assessments of treatments for HIV/AIDS, or associated conditions that may lead to disability or impairment. The remaining 8,932 studies were categorized as either Category 3 or Category 4 studies. Category 3 studies informed background research during report writing. Category 4 studies did not meet the inclusion criteria and were not included in the study.



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