FIGURE 4-1 Plot of NIH grants for illustrative rare diseases by disease prevalence.
NOTE: Prevalence figures come from Orphanet, 2009 (see discussion of data in Chapter 2). Grant numbers include American Recovery and Reinvestment Act grant supplements and training grants.
SOURCE: NIH Reporter (http://projectreporter.nih.gov/reporter.cfm).
A — Progeria
B — Niemann-Pick disease
C — Fanconi anemia
D — Ehlers-Danlos syndrome (classic)
E — Primary ciliary dyskinesia
F — Rett syndrome
G — Duchenne muscular dystrophy
H — Huntington disease
I — Tuberous sclerosis
J — Leber congenital amaurosis
K — Sickle cell anemia
L — Cystic fibrosis
M — Acute myeloid leukemia
N — Congenital diaphragmatic hernia
O — Sarcoidosis
P — Familial dilated cardiomyopathy
Q — Hereditary spherocytosis
R — Turner syndrome
S — Gastric cancer
T — Neurofibromatosis (type 1)
U — Alpha1-antitrypsin
V — Marfan syndrome
W — Amyloidosis
X— Acute respiratory distress syndrome (adult)
Y — Cryptosporidiosis
Z — Non-Hodgkin lymphoma
1— Albright hereditary
osteodystrophy
2 — Scleroderma
3 — Tetralogy of Fallot
4 — Narcolepsy (cataplexy)
5— Melanocortin-4 receptor deficiency
6 — Noonan syndrome
