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Implementing the New Biology: Decadal Challenges Linking Food, Energy, and the Environment: Summary of a Workshop, June 3-4, 2010 (2010)
Board on Life Sciences (BLS)

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. "Appendix B: Workshop Background." Implementing the New Biology: Decadal Challenges Linking Food, Energy, and the Environment: Summary of a Workshop, June 3-4, 2010. Washington, DC: The National Academies Press, 2010.

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Implementing the New Biology: Decadal Challenges Linking Food, Energy, and the Environment - Summary of a Workshop June 3-4, 2010

Appendix B
Workshop Background

WORKSHOP STATEMENT OF TASK

The 2009 report A New Biology for the 21st Century offered a vision that enables powerful advances in the life sciences to provide solutions to major global problems. As part of the follow-on activities stemming from the report, the Board on Life Sciences plans to organize a series of workshops to provide concrete examples of how the life sciences could contribute to addressing these grand challenges.


For the first of these, an ad hoc committee will organize a public workshop on meeting the intertwined challenges of increasing food and energy resources in a context of environmental stress, in which participants will:

  • Identify a small number of concrete problems for the New Biology to solve—problems that are important and urgent (and therefore inspirational), intractable with current knowledge and technology, but perhaps solvable in a decade.

  • Identify the knowledge gaps that would need to be filled to achieve those goals.

  • Identify conceptual and technological advances essential to achieve those goals.

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35

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Implementing the New Biology: Decadal Challenges Linking Food, Energy, and the Environment - Summary of a Workshop June 3-4, 2010 Appendix B Workshop Background WORKSHOP STATEMENT OF TASK The 2009 report A New Biology for the 21st Century offered a vision that enables powerful advances in the life sciences to provide solutions to major global problems. As part of the follow-on activities stemming from the report, the Board on Life Sciences plans to organize a series of workshops to provide concrete examples of how the life sciences could contribute to addressing these grand challenges. For the first of these, an ad hoc committee will organize a public workshop on meeting the intertwined challenges of increasing food and energy resources in a context of environmental stress, in which participants will: Identify a small number of concrete problems for the New Biology to solve—problems that are important and urgent (and therefore inspirational), intractable with current knowledge and technology, but perhaps solvable in a decade. Identify the knowledge gaps that would need to be filled to achieve those goals. Identify conceptual and technological advances essential to achieve those goals.

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Implementing the New Biology: Decadal Challenges Linking Food, Energy, and the Environment - Summary of a Workshop June 3-4, 2010 MEETING AGENDA IMPLEMENTING THE NEW BIOLOGY: DECADAL CHALLENGES LINKING FOOD, ENERGY, AND THE ENVIRONMENT Board on Life Sciences, National Research Council Howard Hughes Medical Institute (HHMI) 4000 Jones Bridge Road • Chevy Chase, MD 20815 WEDNESDAY, JUNE 2, 2010 6:00 p.m. Light buffet dinner for participants who will be arriving early [Rathskeller Lounge] THURSDAY, JUNE 3, 2010 8:00 a.m. Breakfast available until 9:30 a.m. [Small Dining Room] 10:00 a.m. Plenary #1: Welcome to HHMI; Introduction to Workshop [Small Auditorium] Chair: Robert Tjian, President, Howard Hughes Medical Institute; Professor of Biochemistry and Molecular Biology, University of California, Berkeley Keith Yamamoto, Chair, Board on Life Sciences, National Research Council; Professor of Cellular and Molecular Pharmacology and Executive Vice Dean, School of Medicine, University of California, San Francisco Roger Beachy, Director, National Institute of Food and Agriculture, U.S. Department of Agriculture Steven Koonin, Under Secretary for Science, U.S. Department of Energy 10:30 a.m. “Elevator” Talks [Small Auditorium] Each participant will have three minutes to present his or her transformative idea 12:00 p.m. Breakout #1 (in assigned small groups) during lunch [See breakout group assignment and locations] Discuss elevator talks

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Implementing the New Biology: Decadal Challenges Linking Food, Energy, and the Environment - Summary of a Workshop June 3-4, 2010   Choose top three Big Ideas from elevator talks or develop new transformative ideas by combining, refining, and building on elevator talks, or de novo Place each idea on the New Biology quadrant For each idea, explain the following: Degree of risk or likelihood of success Why it requires cross-agency effort and why it won’t happen any other way Why it’s important: impact, if successful, on agriculture, energy, environment, health 2:15 p.m. Break 2:30 p.m. Plenary #2: Prioritization [Small Auditorium] Breakout group progress reports Plenary Discussion: prioritize Refine and perhaps begin to cluster ideas Initial brainstorming on cross-cutting knowledge areas and technologies or shared resources that might contribute to multiple “decadal challenges” 4:00 p.m. Breakout #2 [See breakout group assignments and locations] Begin to identify the “decadal-level” research problems and questions that investigators could address in order to achieve them Questions include the following: What is needed in terms of basic knowledge, new technologies, and infrastructure? What other fields need to be involved? What educational programs are needed to produce the right kinds of researchers? Consideration of timing, sequence, and interactions among ideas 5:30 p.m. Break 6:15 p.m. Dinner (in mixed groups) [Small Dining Room] Representative from each group should brief dinner companions on the day’s discussions; scribes take notes 8:00 p.m. Continued interactions and discussion [Rathskeller Lounge] Steering committee meeting with rapporteurs

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Implementing the New Biology: Decadal Challenges Linking Food, Energy, and the Environment - Summary of a Workshop June 3-4, 2010 FRIDAY, JUNE 4, 2010 7:30 a.m. Breakfast available until 8:30 a.m. [Small Dining Room] 8:30 a.m. Plenary #3: Development of Decadal-Level Agenda [Small Auditorium] Reports of dinner discussions Development of master chart Organization of Breakout #3 10:00 a.m. Break 10:15 a.m. Breakout #3 (as determined in plenary #3) [Rooms N-140, N-238, S-221] 11:30 a.m. Plenary #4: Small-Group Breakout Reports [Small Auditorium] 12:30 p.m. Lunch (Steering committee and rapporteurs meet again) [Small Dining Room] 1:30 p.m. Breakout #4: Gap Filling (as determined over lunch) [Rooms N-140, N-238, S-221] Goal is to capture all ideas: the resulting workshop report will include only ideas discussed at the workshop 2:30 p.m. Final Plenary [Small Auditorium] Identify immediate priorities: top five actions that need to happen in the next year Getting the message out: brainstorming on how participants can continue to be involved in the New Biology effort 3:30 p.m. Adjourn Direct and in-kind support for the workshop has been provided by the U.S. Department of Energy, U.S. Department of Agriculture, Gordon and Betty Moore Foundation, and Howard Hughes Medical Institute. A New Biology for the 21st Century was supported by the National Institutes of Health, the National Science Foundation, and the U.S. Department of Energy.

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Implementing the New Biology: Decadal Challenges Linking Food, Energy, and the Environment - Summary of a Workshop June 3-4, 2010 LIST OF PARTICIPANTS IMPLEMENTING THE NEW BIOLOGY: DECADAL CHALLENGES LINKING FOOD, ENERGY AND THE ENVIRONMENT Board on Life Sciences, National Research Council June 3-4, 2010 • Howard Hughes Medical Institute, Chevy Chase, Maryland Bonnie L. Bassler, Ph.D. HHMI Investigator Squibb Professor of Molecular Biology Princeton University Roger N. Beachy, Ph.D. Director National Institute of Food and Agriculture U.S. Department of Agriculture Edward S. Buckler, Ph.D. Agricultural Research Service U.S. Department of Agriculture; and Adjunct Professor of Plant Breeding and Genetics Cornell University Vicki L. Chandler, Ph.D. [planning committee] Chief Program Officer, Science Gordon & Betty Moore Foundation; and Regents’ Professor, Departments of Plant Sciences and Molecular & Cellular Biology University of Arizona Jeffery L. Dangl, Ph.D. John N. Couch Professor of Biology University of North Carolina at Chapel Hill Edward F. DeLong, Ph.D. Professor, Department of Civil & Environmental Engineering and Division of Biological Engineering Massachusetts Institute of Technology Joseph R. Ecker, Ph.D. Professor, Plant Molecular and Cellular Biology Laboratory Salk Institute for Biological Studies Sean R. Eddy, Ph.D. Group Leader Janelia Farm Research Campus Howard Hughes Medical Institute Richard Flavell, Ph.D., FRS, CBE Chief Scientific Officer Ceres, Inc.

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Implementing the New Biology: Decadal Challenges Linking Food, Energy, and the Environment - Summary of a Workshop June 3-4, 2010 Jeffrey I. Gordon [planning committee] Dr. Robert J. Glaser Distinguished University Professor Director, Center for Genome Sciences School of Medicine Washington University in St. Louis Steve A. Kay, Ph.D. Dean, Division of Biological Sciences Richard C. Atkinson Chair in the Biological Sciences Professor, Cell and Developmental Biology University of California, San Diego Steven E. Koonin, Ph.D. Under Secretary for Science U.S. Department of Energy Stephen P. Long, Ph.D. Robert Emerson Professor Departments of Plant Biology and Crop Sciences University of Illinois at Urbana-Champaign; and Deputy Director Energy Biosciences Institute James A. MacMahon, Ph.D. Dean, College of Science Trustee Professor, Department of Biology Director, Ecology Center Utah State University; and Chair, Board of Directors National Ecological Observatory Network, Inc. Rebecca J. Nelson, Ph.D. Associate Professor, Departments of Plant Pathology & Plant-Microbe Biology and Plant Breeding & Genetics Cornell University; and Scientific Director, McKnight Foundation Collaborative Crop Research Program Donald R. Ort, Ph.D. Professor of Plant Biology University of Illinois at Urbana-Champaign; and Photosynthesis Research Unit Agricultural Research Service U.S. Department of Agriculture Ann H. Reid Director American Academy of Microbiology American Society for Microbiology Charles W. Rice, Ph.D. University Distinguished Professor, Soil Microbiology Department of Agronomy Kansas State University; and President-Elect, Soil Science Society of America Martha Schlicher, Ph.D. Bioenergy Lead Monsanto Company

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Implementing the New Biology: Decadal Challenges Linking Food, Energy, and the Environment - Summary of a Workshop June 3-4, 2010 Christopher R. Somerville, Ph.D. [planning committee] Director Energy Biosciences Institute; and Professor of Plant and Microbial Biology University of California, Berkeley; and Visiting Scientist Lawrence Berkeley National Laboratory Gary Stacey, Ph.D. Missouri Soybean Biotechnology Professor in Functional Genomics and Integrated Advanced Technologies Professor of Plant Sciences and Joint Professor of Biochemistry Director, Center for Sustainable Energy University of Missouri; and Associate Director, National Center for Soybean Biotechnology Gregory Stephanopoulos, Ph.D. Professor of Chemical Engineering Massachusetts Institute of Technology Julie A. Theriot, Ph.D. HHMI Investigator Associate Professor of Biochemistry and Microbiology & Immunology Stanford University Robert Tjian, Ph.D. President Howard Hughes Medical Institute; and Professor of Biochemistry and Molecular Biology University of California, Berkeley Keith Yamamoto, Ph.D. [planning committee] Professor of Cellular and Molecular Pharmacology Executive Vice Dean, School of Medicine University of California, San Francisco AGENCY OBSERVERS Roland F. Hirsh, Ph.D. Program Manager, Climate & Environmental Sciences Division Office of Biological & Environmental Research U.S. Department of Energy Lynn Hudson, Ph.D. Director Office of Science Policy Analysis Office of Science Policy Office of the Director National Institutes of Health Tom Kalil Deputy Director for Policy Office of Science and Technology Policy Executive Office of the President

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Implementing the New Biology: Decadal Challenges Linking Food, Energy, and the Environment - Summary of a Workshop June 3-4, 2010 Mary E. Maxon, Ph.D. Deputy Executive Director President’s Council of Advisors on Science and Technology (PCAST) Philip S. Perlman, Ph.D. Senior Scientific Officer Director, Research Facilities Howard Hughes Medical Institute Carl D. Rhodes, Ph.D. Senior Scientific Officer Howard Hughes Medical Institute Zeev Rosenzweig, Ph.D. Program Officer Division of Chemistry Directorate for Mathematical & Physical Sciences National Science Foundation Joann P. Roskoski, Ph.D. Acting Assistant Director for Biological Sciences National Science Foundation Sharlene C. Weatherwax, Ph.D. Director, Biological Systems Science Division Office of Biological & Environmental Research U.S. Department of Energy NATIONAL ACADEMIES STAFF Lida Anestidou, D.V.M., Ph.D. (LAnestidou@nas.edu) Senior Program Officer Institute for Laboratory Animal Research National Research Council Adam P. Fagen, Ph.D. (AFagen@nas.edu) Senior Program Officer Board on Life Sciences National Research Council India Hook-Barnard, Ph.D. (IHook@nas.edu) Program Officer Board on Life Sciences National Research Council Jo L. Husbands, Ph.D. (JHusbands@nas.edu) Scholar, Senior Project Director Board on Life Sciences National Research Council Robin Schoen (RSchoen@nas.edu) Director Board on Agriculture and Natural Resources National Research Council Frances E. Sharples, Ph.D. (FSharples@nas.edu) Senior Director Board on Life Sciences National Research Council Paula Tarnapol Whitacre (ptw@fullcircle.org) Consultant Science Writer; and Principal Full Circle Communications, LLC