Session 2 Clinical Research and Translational Science—
Accommodating and Enabling Nanotechnology
Moderator: Steven Curley,MD Anderson Cancer Center

Each speaker is asked to comment on the flow of translational research:

– What does a clinical investigator planning trials incorporating nanotechnology need to know?

– What will it take to get there?

Clinical Research Perspective
Speakers are asked to address the following questions:

– What do clinical researchers need to know about nanotechnology?

– What tests must nano-materials themselves undergo?

– What tests must nano-materials themselves undergo?

– What are potential and known risks with use of nanotechnology and how are unknowns being addressed?

– Are there real advantages to nanotechnology (as diagnostics, screening tools, therapeutics, etc.)?

 

11:00 am Nanoparticles as Therapeutic Platforms Steve Libutti, Albert Einstein School of Medicine

11:30 am Biologic Barriers to In Vivo Nanomedicine Delivery: Major Hurdles for Clinical Translation King Li, The Methodist Hospital Research Institute

12:00 pm LUNCH

Industry Perspective
Speakers are asked to address the following questions:

– How are companies thinking about moving nanotechnology

– How are companies thinking about moving nanotechnology products through the pipeline from proof of concept to development for clinical trials?

– What is the current state of preclinical studies in testing efficacy and toxicity?

– What are the long-term effects of these incredibly stable products?

– What are the long-term effects of these incredibly stable products?

– Is it known what happens in degradation processes?

– Is it known what happens in degradation processes?

 

1:00 pm The nab-Platform: From Bench to the Clinic and Beyond
Neil Desai,
Abraxis Biosciences

Preventive Medicine Perspective
Speakers are asked to address the following questions:

– What issues, opportunities, and known efforts exist

– What issues, opportunities, and known efforts exist within this domain?



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