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Dietary Reference Intakes for Calcium and Vitamin D (2011)
Food and Nutrition Board (FNB)

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. "Summary Tables: Dietary Reference Intakes." Dietary Reference Intakes for Calcium and Vitamin D. Washington, DC: The National Academies Press, 2011.

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DRI Dietary Reference Intakes Calcium Vitamin D

Summary Tables
Dietary Reference Intakes

Estimated Average Requirements

Recommended Dietary Allowances and Adequate Intakes, Vitamins

Recommended Dietary Allowances and Adequate Intakes, Elements

Recommended Dietary Allowances and Adequate Intakes, Total Water and Macronutrients

Acceptable Macronutrient Distribution Ranges

Additional Macronutrient Recommendations

Tolerable Upper Intake Levels, Vitamins

Tolerable Upper Intake Levels, Elements

Page
1103
Front Matter (R1-R16)
Summary (1-14)
1 Introduction (15-34)
2 Overview of Calcium (35-74)
3 Overview of Vitamin D (75-124)
4 Review of Potential Indicators of Adequacy and Selection of Indicators: Calcium and Vitamin D (125-344)
5 Dietary Reference Intakes for Adequacy: Calcium and Vitamin D (345-402)
6 Tolerable Upper Intake Levels: Calcium and Vitamin D (403-456)
7 Dietary Intake Assessment (457-478)
8 Implications and Special Concerns (479-512)
9 Information Gaps and Research Needs (513-522)
Appendix A: Acronyms, Abbreviations, and Glossary (523-536)
Appendix B: Issues and Interests Identified by Study Sponsors (537-538)
Appendix C: Methods and Results from the AHRQ-Ottawa Evidence-Based Report on Effectiveness and Safety of Vitamin D in Relation to Bone Health (539-724)
Appendix D: Methods and Results from the AHRQ-Tufts Evidence-Based Report on Vitamin D and Calcium (725-1012)
Appendix E: Literature Search Strategy (1013-1018)
Appendix F: Evidence Maps (1019-1024)
Appendix G: Cases Studies of Vitamin D Toxicity (1025-1034)
Appendix H: Estimated Intakes of Calcium and Vitamin D from National Surveys (1035-1044)
Appendix I: Proportion of the Population Above and Below 40 nmol/L Serum 25-Hydroxyvitamin D Concentrations and Cumulative Distribution of Serum 25-Hydroxyvitamin D Concentrations: United States and Canada (1045-1058)
Appendix J: Workshop Agenda and Open Session Agendas (1059-1064)
Appendix K: Biographical Sketches of Committee Members (1065-1074)
Index (1075-1102)
Summary Tables: Dietary Reference Intakes (1103-1116)

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DRI Dietary Reference Intakes Calcium Vitamin D Summary Tables Dietary Reference Intakes Estimated Average Requirements Recommended Dietary Allowances and Adequate Intakes, Vitamins Recommended Dietary Allowances and Adequate Intakes, Elements Recommended Dietary Allowances and Adequate Intakes, Total Water and Macronutrients Acceptable Macronutrient Distribution Ranges Additional Macronutrient Recommendations Tolerable Upper Intake Levels, Vitamins Tolerable Upper Intake Levels, Elements

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DRI Dietary Reference Intakes Calcium Vitamin D Dietary Reference Intakes (DRIs): Estimated Average Requirements Food and Nutrition Board, Institute of Medicine, National Academies Life Stage Group Calcium (mg/d) CHO (g/kg/d) Protein (g/d) Vit A (μg/d)a Vit C (mg/d) Vit D (μg/d) Vit E (mg/d)b Thiamin (mg/d) Riboflavin (mg/d) Niacin (mg/d)c Infants                     0–6 mo                     6–12 mo     1.0               Children                     1–3 y 500 100 0.87 210 13 10 5 0.4 0.4 5 4–8 y 800 100 0.76 275 22 10 6 0.5 0.5 6 Males                     9–13 y 1,100 100 0.76 445 39 10 9 0.7 0.8 9 14–18 y 1,100 100 0.73 630 63 10 12 1.0 1.1 12 19–30 y 800 100 0.66 625 75 10 12 1.0 1.1 12 31–50 y 800 100 0.66 625 75 10 12 1.0 1.1 12 51–70 y 800 100 0.66 625 75 10 12 1.0 1.1 12 > 70 y 1,000 100 0.66 625 75 10 12 1.0 1.1 12 Females                     9–13 y 1,100 100 0.76 420 39 10 9 0.7 0.8 9 14–18 y 1,100 100 0.71 485 56 10 12 0.9 0.9 11 19–30 y 800 100 0.66 500 60 10 12 0.9 0.9 11 31–50 y 800 100 0.66 500 60 10 12 0.9 0.9 11 51–70 y 1,000 100 0.66 500 60 10 12 0.9 0.9 11 > 70 y 1,000 100 0.66 500 60 10 12 0.9 0.9 11 Pregnancy                     14–18 y 1,000 135 0.88 530 66 10 12 1.2 1.2 14 19–30 y 800 135 0.88 550 70 10 12 1.2 1.2 14 31–50 y 800 135 0.88 550 70 10 12 1.2 1.2 14 Lactation                     14–18 y 1,000 160 1.05 885 96 10 16 1.2 1.3 13 19–30 y 800 160 1.05 900 100 10 16 1.2 1.3 13 31–50 y 800 160 1.05 900 100 10 16 1.2 1.3 13 NOTE: An Estimated Average Requirement (EAR) is the average daily nutrient intake level estimated to meet the requirements of half of the healthy individuals in a group. EARs have not been established for vitamin K, pantothenic acid, biotin, choline, chromium, fluoride, manganese, or other nutrients not yet evaluated via the DRI process. aAs retinol activity equivalents (RAEs). 1 RAE = 1 μg retinol, 12 μg β-carotene, 24 μg α-carotene, or 24 μg β-cryptoxanthin. The RAE for dietary provitamin A carotenoids is two-fold greater than retinol equivalents (RE), whereas the RAE for preformed vitamin A is the same as RE. bAs α-tocopherol. α-tocopherol includes RRR-α-tocopherol, the only form of α-tocopherol that occurs naturally in foods, and the 2R-stereoisomeric forms of α-tocopherol (RRR-, RSR-, RRS-, and RSS-α-tocopherol) that occur in fortified foods and supplements. It does not include the 2S-stereoisomeric forms of α-tocopherol (SRR-, SSR-, SRS-, and SSS-α-tocopherol), also found in fortified foods and supplements.

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DRI Dietary Reference Intakes Calcium Vitamin D Vit B6 (mg/d) Folate (μg/d)d Vit B12 (μg/d) Copper (μg/d) Iodine (μg/d) Iron (mg/d) Magnesium (mg/d) Molybdenum (μg/d) Phosphorus (mg/d) Selenium (μg/d) Zinc (mg/d)           6.9         2.5 0.4 120 0.7 260 65 3.0 65 13 380 17 2.5 0.5 160 1.0 340 65 4.1 110 17 405 23 4.0 0.8 250 1.5 540 73 5.9 200 26 1,055 35 7.0 1.1 330 2.0 685 95 7.7 340 33 1,055 45 8.5 1.1 320 2.0 700 95 6 330 34 580 45 9.4 1.1 320 2.0 700 95 6 350 34 580 45 9.4 1.4 320 2.0 700 95 6 350 34 580 45 9.4 1.4 320 2.0 700 95 6 350 34 580 45 9.4 0.8 250 1.5 540 73 5.7 200 26 1,055 35 7.0 1.0 330 2.0 685 95 7.9 300 33 1,055 45 7.3 1.1 320 2.0 700 95 8.1 255 34 580 45 6.8 1.1 320 2.0 700 95 8.1 265 34 580 45 6.8 1.3 320 2.0 700 95 5 265 34 580 45 6.8 1.3 320 2.0 700 95 5 265 34 580 45 6.8 1.6 520 2.2 785 160 23 335 40 1,055 49 10.5 1.6 520 2.2 800 160 22 290 40 580 49 9.5 1.6 520 2.2 800 160 22 300 40 580 49 9.5 1.7 450 2.4 985 209 7 300 35 1,055 59 10.9 1.7 450 2.4 1,000 209 6.5 255 36 580 59 10.4 1.7 450 2.4 1,000 209 6.5 265 36 580 59 10.4 cAs niacin equivalents (NE). 1 mg of niacin = 60 mg of tryptophan. dAs dietary folate equivalents (DFE). 1 DFE = 1 μg food folate = 0.6 μg of folic acid from fortified food or as a supplement consumed with food = 0.5 μg of a supplement taken on an empty stomach. SOURCES: Dietary Reference Intakes for Calcium, Phosphorous, Magnesium, Vitamin D, and Fluoride (1997); Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (1998); Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids (2000); Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc (2001); Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids (2002/2005); and Dietary Reference Intakes for Calcium and Vitamin D (2011). These reports may be accessed via www.nap.edu.

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DRI Dietary Reference Intakes Calcium Vitamin D Dietary Reference Intakes (DRIs): Recommended Dietary Allowances and Adequate Intakes, Vitamins Food and Nutrition Board, Institute of Medicine, National Academies Life Stage Group Vitamin A (μg/d)a Vitamin C (mg/d) Vitamin D (μg/d)b,c Vitamin E (mg/d)d Vitamin K (μg/d) Thiamin (mg/d) Infants             0–6 mo 400* 40* 10* 4* 2.0* 0.2* 6–12 mo 500* 50* 10* 5* 2.5* 0.3* Children             1–3 y 300 15 15 6 30* 0.5 4–8 y 400 25 15 7 55* 0.6 Males             9–13 y 600 45 15 11 60* 0.9 14–18 y 900 75 15 15 75* 1.2 19–30 y 900 90 15 15 120* 1.2 31–50 y 900 90 15 15 120* 1.2 51–70 y 900 90 15 15 120* 1.2 > 70 y 900 90 20 15 120* 1.2 Females             9–13 y 600 45 15 11 60* 0.9 14–18 y 700 65 15 15 75* 1.0 19–30 y 700 75 15 15 90* 1.1 31–50 y 700 75 15 15 90* 1.1 51–70 y 700 75 15 15 90* 1.1 > 70 y 700 75 20 15 90* 1.1 Pregnancy             14–18 y 750 80 15 15 75* 1.4 19–30 y 770 85 15 15 90* 1.4 31–50 y 770 85 15 15 90* 1.4 Lactation             14–18 y 1,200 115 15 19 75* 1.4 19–30 y 1,300 120 15 19 90* 1.4 31–50 y 1,300 120 15 19 90* 1.4 NOTE: This table (taken from the DRI reports, see www.nap.edu) presents Recommended Dietary Allowances (RDAs) in bold type and Adequate Intakes (AIs) in ordinary type followed by an asterisk (*). An RDA is the average daily dietary intake level sufficient to meet the nutrient requirements of nearly all (97–98 percent) healthy individuals in a group. It is calculated from an Estimated Average Requirement (EAR). If sufficient scientific evidence is not available to establish an EAR, and thus calculate an RDA, an AI is usually developed. For healthy breast-fed infants, an AI is the mean intake. The AI for other life stage and gender groups is believed to cover the needs of all healthy individuals in the groups, but lack of data or uncertainty in the data prevent being able to specify with confidence the percentage of individuals covered by this intake. aAs retinol activity equivalents (RAEs). 1 RAE = 1 μg retinol, 12 μg β-carotene, 24 μg α-carotene, or 24 μg β-cryptoxanthin. The RAE for dietary provitamin A carotenoids is two-fold greater than retinol equivalents (REs), whereas the RAE for preformed vitamin A is the same as RE. bAs cholecalciferol. 1 μg cholecalciferol = 40 IU vitamin D. cUnder the assumption of minimal sunlight. dAs α-tocopherol. α-tocopherol includes RRR-α-tocopherol, the only form of α-tocopherol that occurs naturally in foods, and the 2R-stereoisomeric forms of α-tocopherol (RRR-, RSR-, RRS-, and RSS-α-tocopherol) that occur in fortified foods and supplements. It does not include the 2S-stereoisomeric forms of α-tocopherol (SRR-, SSR-, SRS-, and SSS-α-tocopherol), also found in fortified foods and supplements. eAs niacin equivalents (NE). 1 mg of niacin = 60 mg of tryptophan; 0–6 months = preformed niacin (not NE). fAs dietary folate equivalents (DFE). 1 DFE = 1 μg food folate = 0.6 μg of folic acid from fortified food or as a supplement consumed with food = 0.5 μg of a supplement taken on an empty stomach.

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DRI Dietary Reference Intakes Calcium Vitamin D Riboflavin (mg/d) Niacin (mg/d)e Vitamin B6 (mg/d) Folate (μg/d)f Vitamin B12 (μg/d) Pantothenic Acid (mg/d) Biotin (μg/d) Choline (mg/d)g 0.3* 2* 0.1* 65* 0.4* 1.7* 5* 125* 0.4* 4* 0.3* 80* 0.5* 1.8* 6* 150* 0.5 6 0.5 150 0.9 2* 8* 200* 0.6 8 0.6 200 1.2 3* 12* 250* 0.9 12 1.0 300 1.8 4* 20* 375* 1.3 16 1.3 400 2.4 5* 25* 550* 1.3 16 1.3 400 2.4 5* 30* 550* 1.3 16 1.3 400 2.4 5* 30* 550* 1.3 16 1.7 400 2.4h 5* 30* 550* 1.3 16 1.7 400 2.4h 5* 30* 550* 0.9 12 1.0 300 1.8 4* 20* 375* 1.0 14 1.2 400i 2.4 5* 25* 400* 1.1 14 1.3 400i 2.4 5* 30* 425* 1.1 14 1.3 400i 2.4 5* 30* 425* 1.1 14 1.5 400 2.4h 5* 30* 425* 1.1 14 1.5 400 2.4h 5* 30* 425* 1.4 18 1.9 600j 2.6 6* 30* 450* 1.4 18 1.9 600j 2.6 6* 30* 450* 1.4 18 1.9 600j 2.6 6* 30* 450* 1.6 17 2.0 500 2.8 7* 35* 550* 1.6 17 2.0 500 2.8 7* 35* 550* 1.6 17 2.0 500 2.8 7* 35* 550* gAlthough AIs have been set for choline, there are few data to assess whether a dietary supply of choline is needed at all stages of the life cycle, and it may be that the choline requirement can be met by endogenous synthesis at some of these stages. hBecause 10 to 30 percent of older people may malabsorb food-bound B12, it is advisable for those older than 50 years to meet their RDA mainly by consuming foods fortified with B12 or a supplement containing B12. iIn view of evidence linking folate intake with neural tube defects in the fetus, it is recommended that all women capable of becoming pregnant consume 400 μg from supplements or fortified foods in addition to intake of food folate from a varied diet. jIt is assumed that women will continue consuming 400 μg from supplements or fortified food until their pregnancy is confirmed and they enter prenatal care, which ordinarily occurs after the end of the periconceptional period—the critical time for formation of the neural tube. SOURCES: Dietary Reference Intakes for Calcium, Phosphorous, Magnesium, Vitamin D, and Fluoride (1997); Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (1998); Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids (2000); Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc (2001); Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate (2005); and Dietary Reference Intakes for Calcium and Vitamin D (2011). These reports may be accessed via www.nap.edu.

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DRI Dietary Reference Intakes Calcium Vitamin D Dietary Reference Intakes (DRIs): Recommended Dietary Allowances and Adequate Intakes, Elements Food and Nutrition Board, Institute of Medicine, National Academies Life Stage Group Calcium (mg/d) Chromium (μg/d) Copper (μg/d) Fluoride (mg/d) Iodine (μg/d) Iron (mg/d) Magnesium (mg/d) Manganese (mg/d) Infants                 0–6 mo 200* 0.2* 200* 0.01* 110* 0.27* 30* 0.003* 6–12 mo 260* 5.5* 220* 0.5* 130* 11 75* 0.6* Children                 1–3 y 700 11* 340 0.7* 90 7 80 1.2* 4–8 y 1,000 15* 440 1* 90 10 130 1.5* Males                 9–13 y 1,300 25* 700 2* 120 8 240 1.9* 14–18 y 1,300 35* 890 3* 150 11 410 2.2* 19–30 y 1,000 35* 900 4* 150 8 400 2.3* 31–50 y 1,000 35* 900 4* 150 8 420 2.3* 51–70 y 1,000 30* 900 4* 150 8 420 2.3* > 70 y 1,200 30* 900 4* 150 8 420 2.3* Females                 9–13 y 1,300 21* 700 2* 120 8 240 1.6* 14–18 y 1,300 24* 890 3* 150 15 360 1.6* 19–30 y 1,000 25* 900 3* 150 18 310 1.8* 31–50 y 1,000 25* 900 3* 150 18 320 1.8* 51–70 y 1,200 20* 900 3* 150 8 320 1.8* > 70 y 1,200 20* 900 3* 150 8 320 1.8* Pregnancy                 14–18 y 1,300 29* 1,000 3* 220 27 400 2.0* 19–30 y 1,000 30* 1,000 3* 220 27 350 2.0* 31–50 y 1,000 30* 1,000 3* 220 27 360 2.0* Lactation                 14–18 y 1,300 44* 1,300 3* 290 10 360 2.6* 19–30 y 1,000 45* 1,300 3* 290 9 310 2.6* 31–50 y 1,000 45* 1,300 3* 290 9 320 2.6* NOTE: This table (taken from the DRI reports, see www.nap.edu) presents Recommended Dietary Allowances (RDAs) in bold type and Adequate Intakes (AIs) in ordinary type followed by an asterisk (*). An RDA is the average daily dietary intake level sufficient to meet the nutrient requirements of nearly all (97–98 percent) healthy individuals in a group. It is calculated from an Estimated Average Requirement (EAR). If sufficient scientific evidence is not available to establish an EAR, and thus calculate an RDA, an AI is usually developed. For healthy breast-fed infants, an AI is the mean intake. The AI for other life stage and gender groups is believed to cover the needs of all healthy individuals in the groups, but lack of data or uncertainty in the data prevent being able to specify with confidence the percentage of individuals covered by this intake.

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DRI Dietary Reference Intakes Calcium Vitamin D Molybdenum (μg/d) Phosphorus (mg/d) Selenium (μg/d) Zinc (mg/d) Potassium (g/d) Sodium (g/d) Chloride (g/d) 2* 100* 15* 2* 0.4* 0.12* 0.18* 3* 275* 20* 3 0.7* 0.37* 0.57* 17 460 20 3 3.0* 1.0* 1.5* 22 500 30 5 3.8* 1.2* 1.9* 34 1,250 40 8 4.5* 1.5* 2.3* 43 1,250 55 11 4.7* 1.5* 2.3* 45 700 55 11 4.7* 1.5* 2.3* 45 700 55 11 4.7* 1.5* 2.3* 45 700 55 11 4.7* 1.3* 2.0* 45 700 55 11 4.7* 1.2* 1.8* 34 1,250 40 8 4.5* 1.5* 2.3* 43 1,250 55 9 4.7* 1.5* 2.3* 45 700 55 8 4.7* 1.5* 2.3* 45 700 55 8 4.7* 1.5* 2.3* 45 700 55 8 4.7* 1.3* 2.0* 45 700 55 8 4.7* 1.2* 1.8* 50 1,250 60 12 4.7* 1.5* 2.3* 50 700 60 11 4.7* 1.5* 2.3* 50 700 60 11 4.7* 1.5* 2.3* 50 1,250 70 13 5.1* 1.5* 2.3* 50 700 70 12 5.1* 1.5* 2.3* 50 700 70 12 5.1* 1.5* 2.3* SOURCES: Dietary Reference Intakes for Calcium, Phosphorous, Magnesium, Vitamin D, and Fluoride (1997); Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (1998); Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids (2000); Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc (2001); Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate (2005); and Dietary Reference Intakes for Calcium and Vitamin D (2011). These reports may be accessed via www.nap.edu.

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DRI Dietary Reference Intakes Calcium Vitamin D Dietary Reference Intakes (DRIs): Recommended Dietary Allowances and Adequate Intakes, Total Water and Macronutrients Food and Nutrition Board, Institute of Medicine, National Academies Life Stage Group Total Watera (L/d) Carbohydrate (g/d) Total Fiber (g/d) Fat (g/d) Linoleic Acid (g/d) α-Linolenic Acid (g/d) Proteinb (g/d) Infants               0–6 mo 0.7* 60* ND 31* 4.4* 0.5* 9.1* 6–12 mo 0.8* 95* ND 30* 4.6* 0.5* 11.0 Children               1–3 y 1.3* 130 19* NDc 7* 0.7* 13 4–8 y 1.7* 130 25* ND 10* 0.9* 19 Males               9–13 y 2.4* 130 31* ND 12* 1.2* 34 14–18 y 3.3* 130 38* ND 16* 1.6* 52 19–30 y 3.7* 130 38* ND 17* 1.6* 56 31–50 y 3.7* 130 38* ND 17* 1.6* 56 51–70 y 3.7* 130 30* ND 14* 1.6* 56 > 70 y 3.7* 130 30* ND 14* 1.6* 56 Females               9–13 y 2.1* 130 26* ND 10* 1.0* 34 14–18 y 2.3* 130 26* ND 11* 1.1* 46 19–30 y 2.7* 130 25* ND 12* 1.1* 46 31–50 y 2.7* 130 25* ND 12* 1.1* 46 51–70 y 2.7* 130 21* ND 11* 1.1* 46 > 70 y 2.7* 130 21* ND 11* 1.1* 46 Pregnancy               14–18 y 3.0* 175 28* ND 13* 1.4* 71 19–30 y 3.0* 175 28* ND 13* 1.4* 71 31–50 y 3.0* 175 28* ND 13* 1.4* 71 Lactation               14–18 3.8* 210 29* ND 13* 1.3* 71 19–30 y 3.8* 210 29* ND 13* 1.3* 71 31–50 y 3.8* 210 29* ND 13* 1.3* 71 NOTE: This table (take from the DRI reports, see www.nap.edu) presents Recommended Dietary Allowances (RDA) in bold type and Adequate Intakes (AI) in ordinary type followed by an asterisk (*). An RDA is the average daily dietary intake level sufficient to meet the nutrient requirements of nearly all (97–98 percent) healthy individuals in a group. It is calculated from an Estimated Average Requirement (EAR). If sufficient scientific evidence is not available to establish an EAR, and thus calculate an RDA, an AI is usually developed. For healthy breast-fed infants, an AI is the mean intake. The AI for other life stage and gender groups is believed to cover the needs of all healthy individuals in the groups, but lack of data or uncertainty in the data prevent being able to specify with confidence the percentage of individuals covered by this intake. aTotal water includes all water contained in food, beverages, and drinking water. bBased on g protein per kg of body weight for the reference body weight, e.g., for adults 0.8 g/kg body weight for the reference body weight. cNot determined. SOURCE: Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids (2002/2005) and Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate (2005). The report may be accessed via www.nap.edu.

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DRI Dietary Reference Intakes Calcium Vitamin D Dietary Reference Intakes (DRIs): Acceptable Macronutrient Distribution Ranges Food and Nutrition Board, Institute of Medicine, National Academies Macronutrient Range (percent of energy) Children, 1–3 y Children, 4–18 y Adults Fat 30–40 25–35 20–35 n-6 polyunsaturated fatty acidsa (linoleic acid) 5–10 5–10 5–10 n-3 polyunsaturated fatty acidsa (α-linolenic acid) 0.6–1.2 0.6–1.2 0.6–1.2 Carbohydrate 45–65 45–65 45–65 Protein 5–20 10–30 10–35 aApproximately 10 percent of the total can come from longer-chain n-3 or n-6 fatty acids. SOURCE: Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids (2002/2005). The report may be accessed via www.nap.edu. Dietary Reference Intakes (DRIs): Additional Macronutrient Recommendations Food and Nutrition Board, Institute of Medicine, National Academies Macronutrient Recommendation Dietary cholesterol As low as possible while consuming a nutritionally adequate diet Trans fatty acids As low as possible while consuming a nutritionally adequate diet Saturated fatty acids As low as possible while consuming a nutritionally adequate diet Added sugarsa Limit to no more than 25% of total energy aNot a recommended intake. A daily intake of added sugars that individuals should aim for to achieve a healthful diet was not set. SOURCE: Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids (2002/2005). The report may be accessed via www.nap.edu.

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DRI Dietary Reference Intakes Calcium Vitamin D Dietary Reference Intakes (DRIs): Tolerable Upper Intake Levels, Vitamins Food and Nutrition Board, Institute of Medicine, National Academies Life Stage Group Vitamin A (μg/d)a Vitamin C (mg/d) Vitamin D (μg/d) Vitamin E (mg/d)b,c Vitamin K Thiamin Riboflavin Infants               0–6 mo 600 NDe 25 ND ND ND ND 6–12 mo 600 ND 38 ND ND ND ND Children               1−3 y 600 400 63 200 ND ND ND 4−8 y 900 650 75 300 ND ND ND Males               9−13 y 1,700 1,200 100 600 ND ND ND 14−18 y 2,800 1,800 100 800 ND ND ND 19−30 y 3,000 2,000 100 1,000 ND ND ND 31−50 y 3,000 2,000 100 1,000 ND ND ND 51−70 y 3,000 2,000 100 1,000 ND ND ND > 70 y 3,000 2,000 100 1,000 ND ND ND Females               9−13 y 1,700 1,200 100 600 ND ND ND 14−18 y 2,800 1,800 100 800 ND ND ND 19−30 y 3,000 2,000 100 1,000 ND ND ND 31−50 y 3,000 2,000 100 1,000 ND ND ND 51−70 y 3,000 2,000 100 1,000 ND ND ND > 70 y 3,000 2,000 100 1,000 ND ND ND Pregnancy               14−18 y 2,800 1,800 100 800 ND ND ND 19−30 y 3,000 2,000 100 1,000 ND ND ND 31−50 y 3,000 2,000 100 1,000 ND ND ND Lactation               14−18 y 2,800 1,800 100 800 ND ND ND 19−30 y 3,000 2,000 100 1,000 ND ND ND 31−50 y 3,000 2,000 100 1,000 ND ND ND NOTE: A Tolerable Upper Intake Level (UL) is the highest level of daily nutrient intake that is likely to pose no risk of adverse health effects to almost all individuals in the general population. Unless otherwise specified, the UL represents total intake from food, water, and supplements. Due to a lack of suitable data, ULs could not be established for vitamin K, thiamin, riboflavin, vitamin B12, pantothenic acid, biotin, and carotenoids. In the absence of a UL, extra caution may be warranted in consuming levels above recommended intakes. Members of the general population should be advised not to routinely exceed the UL. The UL is not meant to apply to individuals who are treated with the nutrient under medical supervision or to individuals with predisposing conditions that modify their sensitivity to the nutrient. aAs preformed vitamin A only. bAs α-tocopherol; applies to any form of supplemental α-tocopherol. cThe ULs for vitamin E, niacin, and folate apply to synthetic forms obtained from supplements, fortified foods, or a combination of the two.

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DRI Dietary Reference Intakes Calcium Vitamin D Niacin (mg/d)c Vitamin B6 (mg/d) Folate (μg/d)c Vitamin B12 Pantothenic Acid Biotin Choline (g/d) Carotenoidsd ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND 10 30 300 ND ND ND 1.0 ND 15 40 400 ND ND ND 1.0 ND 20 60 600 ND ND ND 2.0 ND 30 80 800 ND ND ND 3.0 ND 35 100 1,000 ND ND ND 3.5 ND 35 100 1,000 ND ND ND 3.5 ND 35 100 1,000 ND ND ND 3.5 ND 35 100 1,000 ND ND ND 3.5 ND 20 60 600 ND ND ND 2.0 ND 30 80 800 ND ND ND 3.0 ND 35 100 1,000 ND ND ND 3.5 ND 35 100 1,000 ND ND ND 3.5 ND 35 100 1,000 ND ND ND 3.5 ND 35 100 1,000 ND ND ND 3.5 ND 30 80 800 ND ND ND 3.0 ND 35 100 1,000 ND ND ND 3.5 ND 35 100 1,000 ND ND ND 3.5 ND 30 80 800 ND ND ND 3.0 ND 35 100 1,000 ND ND ND 3.5 ND 35 100 1,000 ND ND ND 3.5 ND dβ-Carotene supplements are advised only to serve as a provitamin A source for individuals at risk of vitamin A deficiency. eND = Not determinable due to lack of data of adverse effects in this age group and concern with regard to lack of ability to handle excess amounts. Source of intake should be from food only to prevent high levels of intake. SOURCES: Dietary Reference Intakes for Calcium, Phosphorous, Magnesium, Vitamin D, and Fluoride (1997); Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (1998); Dietary Reference Intakes for Vitamin C, Vitamine E, Selenium, and Carotenoids (2000); Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc (2001); and Dietary Reference Intakes for Calcium and Vitamin D (2011). These reports may be accessed via www.nap.edu.

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DRI Dietary Reference Intakes Calcium Vitamin D Dietary Reference Intakes (DRIs): Tolerable Upper Intake Levels, Elements Food and Nutrition Board, Institute of Medicine, National Academies Life Stage Group Arsenica Boron (mg/d) Calcium (mg/d) Chromium Copper (μg/d) Fluoride (mg/d) Iodine (μg/d) Iron (mg/d) Infants                 0–6 mo NDe ND 1,000 ND ND 0.7 ND 40 6–12 mo ND ND 1,500 ND ND 0.9 ND 40 Children                 1-3 y ND 3 2,500 ND 1,000 1.3 200 40 4-8 y ND 6 2,500 ND 3,000 2.2 300 40 Males                 9-13 y ND 11 3,000 ND 5,000 10 600 40 14-18 y ND 17 3,000 ND 8,000 10 900 45 19-30 y ND 20 2,500 ND 10,000 10 1,100 45 31-50 y ND 20 2,500 ND 10,000 10 1,100 45 51-70 y ND 20 2,000 ND 10,000 10 1,100 45 > 70 y ND 20 2,000 ND 10,000 10 1,100 45 Females                 9-13 y ND 11 3,000 ND 5,000 10 600 40 14-18 y ND 17 3,000 ND 8,000 10 900 45 19-30 y ND 20 2,500 ND 10,000 10 1,100 45 31-50 y ND 20 2,500 ND 10,000 10 1,100 45 51-70 y ND 20 2,000 ND 10,000 10 1,100 45 > 70 y ND 20 2,000 ND 10,000 10 1,100 45 Pregnancy                 14-18 y ND 17 3,000 ND 8,000 10 900 45 19-30 y ND 20 2,500 ND 10,000 10 1,100 45 61-50 y ND 20 2,500 ND 10,000 10 1,100 45 Lactation                 14-18 y ND 17 3,000 ND 8,000 10 900 45 19-30 y ND 20 2,500 ND 10,000 10 1,100 45 31-50 y ND 20 2,500 ND 10,000 10 1,100 45 NOTE: A Tolerable Upper Intake Level (UL) is the highest level of daily nutrient intake that is likely to pose no risk of adverse health effects to almost all individuals in the general population. Unless otherwise specified, the UL represents total intake from food, water, and supplements. Due to a lack of suitable data, ULs could not be established for vitamin K, thiamin, riboflavin, vitamin B12, pantothenic acid, biotin, and carotenoids. In the absence of a UL, extra caution may be warranted in consuming levels above recommended intakes. Members of the general population should be advised not to routinely exceed the UL. The UL is not meant to apply to individuals who are treated with the nutrient under medical supervision or to individuals with predisposing conditions that modify their sensitivity to the nutrient. aAlthough the UL was not determined for arsenic, there is no justification for adding arsenic to food or supplements. bThe ULs for magnesium represent intake from a pharmacological agent only and do not include intake from food and water. cAlthough silicon has not been shown to cause adverse effects in humans, there is no justification for adding silicon to supplements.

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DRI Dietary Reference Intakes Calcium Vitamin D Magnesium (mg/d)b Manganese (mg/d) Molybdenum (μg/d) Nickel (mg/d) Phosphorus (g/d) Selenium (μg/d) Siliconc Vanadium (mg/d)d Zinc (mg/d) Sodium (g/d) Chloride (g/d) ND ND ND ND ND 45 ND ND 4 ND ND ND ND ND ND ND 60 ND ND 5 ND ND 65 2 300 0.2 3 90 ND ND 7 1.5 2.3 110 3 600 0.3 3 150 ND ND 12 1.9 2.9 350 6 1,100 0.6 4 280 ND ND 23 2.2 3.4 350 9 1,700 1.0 4 400 ND ND 34 2.3 3.6 350 11 2,000 1.0 4 400 ND 1.8 40 2.3 3.6 350 11 2,000 1.0 4 400 ND 1.8 40 2.3 3.6 350 11 2,000 1.0 4 400 ND 1.8 40 2.3 3.6 350 11 2,000 1.0 3 400 ND 1.8 40 2.3 3.6 350 6 1,100 0.6 4 280 ND ND 23 2.2 3.4 350 9 1,700 1.0 4 400 ND ND 34 2.3 3.6 350 11 2,000 1.0 4 400 ND 1.8 40 2.3 3.6 350 11 2,000 1.0 4 400 ND 1.8 40 2.3 3.6 350 11 2,000 1.0 4 400 ND 1.8 40 2.3 3.6 350 11 2,000 1.0 3 400 ND 1.8 40 2.3 3.6 350 9 1,700 1.0 3.5 400 ND ND 34 2.3 3.6 350 11 2,000 1.0 3.5 400 ND ND 40 2.3 3.6 350 11 2,000 1.0 3.5 400 ND ND 40 2.3 3.6 350 9 1,700 1.0 4 400 ND ND 34 2.3 3.6 350 11 2,000 1.0 4 400 ND ND 40 2.3 3.6 350 11 2,000 1.0 4 400 ND ND 40 2.3 3.6 dAlthough vanadium in food has not been shown to cause adverse effects in humans, there is no justification for adding vanadium to food, and vanadium supplements should be used with caution. The UL is based on adverse effects in laboratory animals, and this data could be used to set a UL for adults but not children and adolescents. eND = Not determinable due to lack of data of adverse effects in this age group and concern with regard to lack of ability to handle excess amounts. Source of intake should be from food only to prevent high levels of intake. SOURCES: Dietary Reference Intakes for Calcium, Phosphorous, Magnesium, Vitamin D, and Fluoride (1997); Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (1998); Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids (2000); Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc (2001); Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate (2005); and Dietary Reference Intakes for Calcium and Vitamin D (2011). These reports may be accessed via www.nap.edu.

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