RCTs

Ala-Houhala et al., 1988

Children, 8–10 y old

IG1: 400 IU vit D₂ 5–7×/wk

CG: placebo

Distal radius BMC (SPA)

Serum 25OHD, mean (SD) (nmol/L)

Baseline (winter):

IG1: 49.3 (19.0) vs. CG: 46.0 (15.5)

Mid-study (autumn):

IG1: 78.0 (24.3) vs. CG 59.0 (17.8)

End-of-study (winter):

IG1: 71.3 (23.4) vs. CG 43.3 (19.5), p < 0.01

n = 60

Finland

13 mo

IG1: 62% female

CG: 48% female

Jadad = 1

Caucasian