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Dietary Reference Intakes for Calcium and Vitamin D (2011)
Food and Nutrition Board (FNB)

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. "6 Tolerable Upper Intake Levels: Calcium and Vitamin D." Dietary Reference Intakes for Calcium and Vitamin D. Washington, DC: The National Academies Press, 2011.

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DRI Dietary Reference Intakes Calcium Vitamin D

TABLE 6-2 Calcium Tolerable Upper Intake Levels (UL) by Life Stage

Life Stage Group

UL

Infants

 

0 to 6 mo

1,000 mg

6 to 12 mo

1,500 mg

Children

 

1–3 y

2,500 mg

4–8 y

2,500 mg

Males

 

9–13 y

3,000 mg

14–18 y

3,000 mg

19–30 y

2,500 mg

31–50 y

2,500 mg

51–70 y

2,000 mg

> 70 y

2,000 mg

Females

 

9–13 y

3,000 mg

14–18 y

3,000 mg

19–30 y

2,500 mg

31–50 y

2,500 mg

51–70 y

2,000 mg

> 70 y

2,000 mg

Pregnancy

 

14–18 y

3,000 mg

19–30 y

2,500 mg

31–50 y

2,500 mg

Lactation

 

14–18 y

3,000 mg

19–30 y

2,500 mg

31–50 y

2,500 mg

Using these same data, Sargent et al. (1999) later reported on calcium excretion measures, and this measure serves as the UL indicator for infants. This 1999 report has provided the ability to estimate a NOAEL for calcium intake for infants based on calcium excretion. Within the confines of the limitations of the data, they suggest that infants can tolerate approximately 1,750 mg of calcium per day with no noted adverse effects. A NOAEL of 1,750 mg/day is therefore established for infants on this basis.

Infants 0 to 6 Months of Age

The presumed sensitivity of the young infant to excess intakes of any substance, as well as the lack of direct evidence to clarify the nature of adverse effects for this group, warrants a cautious approach. Quantitative factors relative to metabolic differences between younger infants and older

Page
419
Front Matter (R1-R16)
Summary (1-14)
1 Introduction (15-34)
2 Overview of Calcium (35-74)
3 Overview of Vitamin D (75-124)
4 Review of Potential Indicators of Adequacy and Selection of Indicators: Calcium and Vitamin D (125-344)
5 Dietary Reference Intakes for Adequacy: Calcium and Vitamin D (345-402)
6 Tolerable Upper Intake Levels: Calcium and Vitamin D (403-456)
7 Dietary Intake Assessment (457-478)
8 Implications and Special Concerns (479-512)
9 Information Gaps and Research Needs (513-522)
Appendix A: Acronyms, Abbreviations, and Glossary (523-536)
Appendix B: Issues and Interests Identified by Study Sponsors (537-538)
Appendix C: Methods and Results from the AHRQ-Ottawa Evidence-Based Report on Effectiveness and Safety of Vitamin D in Relation to Bone Health (539-724)
Appendix D: Methods and Results from the AHRQ-Tufts Evidence-Based Report on Vitamin D and Calcium (725-1012)
Appendix E: Literature Search Strategy (1013-1018)
Appendix F: Evidence Maps (1019-1024)
Appendix G: Cases Studies of Vitamin D Toxicity (1025-1034)
Appendix H: Estimated Intakes of Calcium and Vitamin D from National Surveys (1035-1044)
Appendix I: Proportion of the Population Above and Below 40 nmol/L Serum 25-Hydroxyvitamin D Concentrations and Cumulative Distribution of Serum 25-Hydroxyvitamin D Concentrations: United States and Canada (1045-1058)
Appendix J: Workshop Agenda and Open Session Agendas (1059-1064)
Appendix K: Biographical Sketches of Committee Members (1065-1074)
Index (1075-1102)
Summary Tables: Dietary Reference Intakes (1103-1116)