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Dietary Reference Intakes for Calcium and Vitamin D (2011)
Food and Nutrition Board (FNB)

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. "6 Tolerable Upper Intake Levels: Calcium and Vitamin D." Dietary Reference Intakes for Calcium and Vitamin D. Washington, DC: The National Academies Press, 2011.

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DRI Dietary Reference Intakes Calcium Vitamin D

ULs for Pregnancy and Lactation

Pregnant or Lactating 14 Through 18 Years of Age

Pregnant or Lactating 19 Through 30 Years of Age

Pregnant or Lactating 31 Through 50 Years of Age

 

UL 4,000 IU (100 μg)/day Vitamin D

The available data do not indicate a basis for deriving a UL for pregnant and lactating women or adolescents that is different from those for their non-pregnant and non-lactating counterparts.

REFERENCES

Adams, J. S. and G. Lee. 1997. Gains in bone mineral density with resolution of vitamin D intoxication. Annals of Internal Medicine 127(3): 203-6.

Aloia, J. F., M. Patel, R. Dimaano, M. Li-Ng, S. A. Talwar, M. Mikhail, S. Pollack and J. K. Yeh. 2008. Vitamin D intake to attain a desired serum 25-hydroxyvitamin D concentration. American Journal of Clinical Nutrition 87(6): 1952-8.

Ames, S. K., B. M. Gorham and S. A. Abrams. 1999. Effects of high compared with low calcium intake on calcium absorption and incorporation of iron by red blood cells in small children. American Journal of Clinical Nutrition 70(1): 44-8.

Anthoni, S., E. Savilahti, H. Rautelin and K. L. Kolho. 2009. Milk protein IgG and IgA: the association with milk-induced gastrointestinal symptoms in adults. World Journal of Gastroenterology 15(39): 4915-8.

Asmus, H. G., J. Braun, R. Krause, R. Brunkhorst, H. Holzer, W. Schulz, H. H. Neumayer, P. Raggi and J. Bommer. 2005. Two year comparison of sevelamer and calcium carbonate effects on cardiovascular calcification and bone density. Nephrology, Dialysis, Transplantation 20(8): 1653-61.

Bailey, C. S., J. J. Weiner, O. M. Gibby and M. D. Penney. 2008. Excessive calcium ingestion leading to milk-alkali syndrome. Annals of Clinical Biochemistry 45(Pt 5): 527-9.

Bajwa, G. S., L. M. Morrison and B. H. Ershoff. 1971. Induction of aortic and coronary atheroarteriosclerosis in rats fed a hypervitaminosis D, cholesterol-containing diet. Proceedings of the Society for Experimental Biology and Medicine 138(3): 975-82.

Barger-Lux, M. J. and R. P. Heaney. 2002. Effects of above average summer sun exposure on serum 25-hydroxyvitamin D and calcium absorption. Journal of Clinical Endocrinology and Metabolism 87(11): 4952-6.

Baron, J. A., M. Beach, K. Wallace, M. V. Grau, R. S. Sandler, J. S. Mandel, D. Heber and E. R. Greenberg. 2005. Risk of prostate cancer in a randomized clinical trial of calcium supplementation. Cancer Epidemiology, Biomarkers & Prevention 14(3): 586-9.

Binkley, N., R. Novotny, D. Krueger, T. Kawahara, Y. G. Daida, G. Lensmeyer, B. W. Hollis and M. K. Drezner. 2007. Low vitamin D status despite abundant sun exposure. Journal of Clinical Endocrinology and Metabolism 92(6): 2130-5.

Blank, S., K. S. Scanlon, T. H. Sinks, S. Lett and H. Falk. 1995. An outbreak of hypervitaminosis D associated with the overfortification of milk from a home-delivery dairy. American Journal of Public Health 85(5): 656-9.

Page
446
Front Matter (R1-R16)
Summary (1-14)
1 Introduction (15-34)
2 Overview of Calcium (35-74)
3 Overview of Vitamin D (75-124)
4 Review of Potential Indicators of Adequacy and Selection of Indicators: Calcium and Vitamin D (125-344)
5 Dietary Reference Intakes for Adequacy: Calcium and Vitamin D (345-402)
6 Tolerable Upper Intake Levels: Calcium and Vitamin D (403-456)
7 Dietary Intake Assessment (457-478)
8 Implications and Special Concerns (479-512)
9 Information Gaps and Research Needs (513-522)
Appendix A: Acronyms, Abbreviations, and Glossary (523-536)
Appendix B: Issues and Interests Identified by Study Sponsors (537-538)
Appendix C: Methods and Results from the AHRQ-Ottawa Evidence-Based Report on Effectiveness and Safety of Vitamin D in Relation to Bone Health (539-724)
Appendix D: Methods and Results from the AHRQ-Tufts Evidence-Based Report on Vitamin D and Calcium (725-1012)
Appendix E: Literature Search Strategy (1013-1018)
Appendix F: Evidence Maps (1019-1024)
Appendix G: Cases Studies of Vitamin D Toxicity (1025-1034)
Appendix H: Estimated Intakes of Calcium and Vitamin D from National Surveys (1035-1044)
Appendix I: Proportion of the Population Above and Below 40 nmol/L Serum 25-Hydroxyvitamin D Concentrations and Cumulative Distribution of Serum 25-Hydroxyvitamin D Concentrations: United States and Canada (1045-1058)
Appendix J: Workshop Agenda and Open Session Agendas (1059-1064)
Appendix K: Biographical Sketches of Committee Members (1065-1074)
Index (1075-1102)
Summary Tables: Dietary Reference Intakes (1103-1116)