TABLE E-1 Comparison of Chapter 3 Guidance on Conducting Systematic Reviews (SR) of Comparative Effectiveness Research

Standards and Elements

Agency for Healthcare Research and Quality  (AHRQ) Effective Health Care Program

Centre for Reviews and Dissemination (CRD)

The Cochrane  Collaboration

3.1 Conduct a comprehensive, systematic search for evidence

Provides guidance on searching for evidence (see below).

Provides guidance on searching for evidence (see below).

Provides guidance on searching for evidence (see below).

3.1.1 Work with a librarian or other information specialist trained in performing systematic reviews to plan the search strategy

A person with library expertise is part of the review team whose responsibility is to plan the search. The person conducting the search should be involved in the development of key questions, PICOTS (population, intervention, comparator, outcome, timing, and setting), analytic frameworks, and inclusion/exclusion criteria.

An information specialist should ideally be included as part of the project team.

Review authors should work closely with the Trials Search Coordinator for assistance in searching for studies to include in their reviews.

3.1.2 Design the search strategy to address each key research question

The search strategy should be based on the concepts identified in the analytic framework, and the review question (PICOTS).

Search strategies should be highly sensitive in order to retrieve all potentially relevant studies. Use PICOS (population, intervention, comparator, outcome, and setting) to help structure the search. Consult the topic experts and the advisory team for advice.

Searches are targeted at the eligibility criteria for the review not the review question).

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