Surveillance, Spectrum, and Burden of Tick-Borne Diseases
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Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases: The Short-Term and Long-Term Outcomes - Workshop Report
D
Workshop Agenda
DAY ONE: OCTOBER 11, 2010
8:00 am
Introduction
Lonnie King, D.V.M., M.S., M.A.
Chair, Committee on Lyme Disease and Other Tick-Borne Diseases
Dean, College of Veterinary Medicine
The Ohio State University
8:15 am
A Systems Approach in Understanding Tick-Borne Diseases: People, Animals, and the Ecosystem
Richard Ostfeld, Ph.D.
Disease Ecologist
Cary Institute of Ecosystem Studies
8:40 am
Discussion
Surveillance, Spectrum, and Burden of Tick-Borne Diseases
9:00 am
Moderator: Gordon Schutze, M.D.
Committee Member, Committee on Lyme Disease and Other Tick-Borne Diseases
Professor and Vice-Chairman for Educational Affairs
Department of Pediatrics
Vice President, Baylor International Pediatric AIDS Initiative
Baylor College of Medicine
Texas Children’s Hospital
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Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases: The Short-Term and Long-Term Outcomes - Workshop Report
9:05 am
Landscape of Lyme Disease: Current Knowledge, Gaps, and Research Needs
Gary P. Wormser, M.D.
Professor of Medicine
Chief, Division of Infectious Diseases
Vice-Chairman, Department of Medicine
New York Medical College
9:30 am
Spectrum of Lyme Disease: Approaches to Understanding Multi-factorial and Multidimensional Diseases
Benjamin J. Luft, M.D.
Edmund D. Pellegrino Professor
Division of Infectious Diseases
State University of New York at Stony Brook
9:50 am
Discussion
10:10 am
Break
10:25 am
Clinical Manifestations, Co-infection, and Research Needs of Human Babesiosis: The Increasing Health Burden
Peter Krause, M.D.
Senior Research Scientist
Lecturer in Epidemiology, Microbial Diseases
Yale School of Public Health
10:40 am
Insights into Ehrlichia & Anaplasma: Surveillance, Co-infection, and Research Needs
J. Stephen Dumler, M.D.
Professor, Department of Pathology
Division of Medical Microbiology
Johns Hopkins University School of Medicine
11:00 am
Rickettsia Diseases: Spectrum of Disease, Spatial Clustering, At-Risk Populations, and Research Needs
Jennifer McQuiston, D.V.M, M.S.
National Center for Preparedness, Detection, and Control of Infectious Diseases
Centers for Disease Control and Prevention
11:20 am
Discussion
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11:40 am
Panel: Disease Surveillance & Co-infection
J. Stephen Dumler, Peter Krause, Benjamin J. Luft, Jennifer McQuiston, and Gary P. Wormser
12:15 pm
Summation: Unifying Knowledge Gaps and Needs
Gordon Schutze
12:25 pm
LUNCH (45 minutes)
At-Risk Populations and Human Face of Tick-Borne Diseases
1:10 pm
Moderator: Lonnie King
1:15 pm
Panel: Genetic and Acquired Determinants of Host Susceptibility and Vulnerable Populations
David Weber, M.D.
Professor of Medicine and Pediatrics, School of Medicine
Professor of Epidemiology, School of Public Health
University of North Carolina
Peter Krause, M.D.
Senior Research Scientist
Lecturer in Epidemiology Microbial Diseases
Yale School of Public Health
1:40 pm
Discussion
1:55 pm
The Human Face of Tick-Borne Disease Infections
Pamela Weintraub
Author, Cure Unknown
Features Editor, Discover Magazine
2:15 pm
Discussion
2:55 pm
Break
Diagnostics and Diagnosis
3:05 pm
Moderators: Lynn Gerber, M.D.
Committee Member, Committee on Lyme Disease and Other Tick-Borne Diseases
Director, Center for the Study of Chronic Illness and Disability
College of Health and Human Services
George Mason University
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Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases: The Short-Term and Long-Term Outcomes - Workshop Report
David H. Walker, M.D.
Committee Member, Committee on Lyme Disease and Other Tick-Borne Diseases
Professor and Chair
Department of Pathology
University of Texas Medical Branch at Galveston
3:10 pm
Diagnostics for Lyme Disease: Knowledge Gaps and Needs
Maria Aguero-Rosenfeld, M.D.
Professor of Pathology
Director of Clinical Pathology and Microbiology Laboratory
Bellevue Hospital Center
3:30 pm
Improved Diagnostics & Novel Approaches to Tick-Borne Disease Infections
Juan Olano, M.D.
Associate Professor, Department of Pathology
Director, Residency Training Program
University of Texas Medical Branch Center
3:50 pm
Potential Bio-Marker Applications for Lyme Disease: Aligning Multiple Symptoms with Biological Measures
Afton Hassett, Psy.D.
Associate Research Scientist, Department of Anesthesiology
Chronic Pain & Fatigue Research Center
University of Michigan Medical School
4:10 pm
Discussion
4:40 pm
Panel: Challenges for Clinicians in Diagnosis and Management of Chronic Illness Manifestations: Knowledge Gaps
Sam T. Donta, M.D.
Infectious Disease Specialist
Falmouth Hospital, Massachusetts
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Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases: The Short-Term and Long-Term Outcomes - Workshop Report
Brian Fallon, M.D., M.P.H.
Director of the Center for Neuroinflammatory Disorders and Biobehavioral Medicine
Director of the Lyme and Tick-Borne Diseases Research Center
Columbia University Medical Center
Richard F. Jacobs, M.D., F.A.A.P.
Robert H. Fiser, Jr., M.D. Endowed Chair in Pediatrics
Chairman, Department of Pediatrics
University of Arkansas for Medical Sciences
President, Arkansas Children’s Hospital Research Institute
Matthew Liang, M.D., M.P.H.
Professor, Department of Health Policy and Management
Harvard School of Public Health
5:20 pm
Discussion
5:45 pm
Summation
Lynn Gerber and David Walker
6:00 pm
Adjourn
DAY TWO: OCTOBER 12, 2010
8:00 am
Introduction
Lonnie King
Emerging Infections, Tick Biology, and Host-Vector Interactions
Moderator: Lonnie King
8:05 am
Emerging and Re-Emerging Tick-Borne Infections
Ulrike Munderloh, D.V.M., Ph.D.
Associate Professor, Department of Entomology
University of Minnesota
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8:25 am
Natural History of Ticks: Evolution, Adaptation and Biology
Tom G. Schwan, Ph.D., M.S.
Chief, Laboratory of Zoonotic Pathogens
Chief, Medical Entomology Section
National Institute of Allergy and Infectious Diseases
8:45 am
Wildlife and Domestic Hosts: Their Roles in Maintaining, Amplifying Pathogens, and their Changing Dynamics
Howard Ginsberg, Ph.D.
Research Ecologist
United States Geological Survey
Professor in Residence, Department of Plant Science
University of Rhode Island
9:05 am
Discussion
9:20 am
Comparative Medical Importance of a One Health Approach to Emerging Tick-borne Diseases
Edward Breitschwerdt, D.V.M.
Professor of Internal Medicine
College of Veterinary Medicine
North Carolina State University
Adjunct Professor of Medicine
Duke University Medical Center
9:40 am
Variation of Borrelia Subspecies: Implications for Human Disease
James H. Oliver, Jr., Ph.D.
Director, Institute of Arthropodology and Parasitology
Callaway Professor of Biology
Georgia Southern University
10:00 am
Discussion
10:20 am
Break
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Pathogenesis
10:30 am
Moderator: Guy Palmer, D.V.M., Ph.D.
Committee Member, Committee on Lyme Disease and Other Tick-Borne Diseases
Regents Professor of Pathology and Infectious Diseases
The Creighton Chair and Director, School for Global Animal Health
Washington State University
10:35 am
Pathogenesis of Borrelia burgdorferi Infection and Disease
Janis Weis, Ph.D.
Professor of Pathology, Department of Pathology
University of Utah
10:55 am
Duration of Spirochete Infection Following Antibiotic Treatment in Animals
Linda Bockenstedt, M.D.
Harold W. Jockers Professor of Medicine
Department of Rheumatology
Yale School of Medicine
11:15 am
Discussion
11:30 am
Antigenic Variation as a Mechanism for Persistent Borrelia Infection
Steven Norris, Ph.D.
Greer Professor
Vice Chair for Research
Pathology & Laboratory Medicine
University of Texas, Houston
11:50 am
Sequestration as a Mechanism for Persistent Borrelia Infection
Stephen Barthold, D.V.M., Ph.D.
Distinguished Professor
Department of Pathology, Microbiology and Immunology
Center of Comparative Medicine
School of Veterinary Medicine
University of California, Davis
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Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases: The Short-Term and Long-Term Outcomes - Workshop Report
12:10 pm
Discussion
12:30 pm
LUNCH (45 minutes)
1:15 pm
Pathogenesis of Ehrlichia and Anaplasma Infection and Disease
Nahed Ismail, M.D., M.Sc., Ph.D., S.M. (ASCP), D. (ABMM)
Associate Professor, Department of Pathology
Meharry Medical College
1:35 pm
Pathogenesis of Rickettsia Infection and Disease
Gustavo Valbuena, M.D.
Instructor, Department of Pathology
University of Texas Medical Branch
1:55 pm
Discussion
2:15 pm
Summation
Guy Palmer
Science, Society, and Disease
2:20 pm
Moderator: Lynn Gerber
2:25 pm
The Social Construction of Lyme Disease
Robert Aronowitz, M.D.
Professor, Department of History and Sociology of Science
University of Pennsylvania
2:45 pm
Discussion
2:55 pm
Break
Prevention
3:05 pm
Moderator: Stephen M. Ostroff, M.D.
Committee Member, Committee on Lyme Disease and Other Tick-Borne Diseases
Director, Bureau of Epidemiology
Pennsylvania Department of Health
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Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases: The Short-Term and Long-Term Outcomes - Workshop Report
3:10 pm
Current Vaccines for Tick-Borne Disease Infections and Vaccine Development
Jere McBride, Ph.D., M.S.
Associate Professor, Department of Pathology
University of Texas Medical Branch
3:30 pm
Developing Opportunities for Future Vaccines
Wendy Brown, Ph.D., M.P.H.
Regents Professor, Department of Veterinary Microbiology and Pathology
Washington State University
3:50 pm
Discussion
4:10 pm
Education, Behavior Change, and Other Non-Pharmaceutical Measures Against Lyme and Other Tick-Borne Diseases
Paul Mead, M.D., M.P.H.
Medical Epidemiologist, Division of Vector-Borne Infectious Diseases
National Center for Infectious Diseases
Center for Disease Control and Prevention
4:30 pm
Vector- and Host-Targeted Strategies for Prevention of Tick-Borne Diseases
José M.C. Ribeiro, M.D., Ph.D.
Chief, Vector Biology Section
Laboratory of Malaria and Vector Research
National Institute of Allergy and Infectious Diseases
4:50 pm
Discussion
5:10 pm
Summation
Steve Ostroff
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Closing
5:20 pm
Moderator: Lonnie King
5:25 pm
Panel: State of Science, General Research Gaps and Opportunities in Tick-Borne Diseases
John Aucott, M.D.
Founder, Lyme Disease Research Foundation of Maryland
Physician, Park Medical Associates
Linda Bockenstedt, M.D.
Harold W. Jockers Professor of Medicine
Department of Rheumatology
Yale School of Medicine
J. Stephen Dumler, M.D.
Professor, Department of Pathology
Division of Medical Microbiology
Johns Hopkins University School of Medicine
Susan O’Connell, M.D.
Consultant Microbiologist
Head of the Lyme Borreliosis Unit
Southampton General Hospital
Gregg P. Skall, J.D.
Counsel, National Capital Lyme and Tick-borne Disease Association
Member, Womble Carlyle Sandridge & Rice, PLLC
5:55 pm
Discussion
6:25 pm
Final Summation and Closing Remarks
Lonnie King
6:35 pm
Adjourn