Sogawa K, Numayama-Tsuruta K, Takahashi T, Matsushita N, Miura C, Nikawa J, Gotoh O, Kikuchi Y, Fujii-Kuriyama Y. 2004. A novel induction mechanism of the rat CYP1A2 gene mediated by Ah receptor–ARNT heterodimer. Biochemical and Biophysical Research Communications 318(3):746–755.

Song Z, Pollenz RS. 2002. Ligand-dependent and independent modulation of aryl hydrocarbon receptor localization, degradation, and gene regulation. Molecular Pharmacology 62(4):806–816.

Sorg O, Zennegg M, Schmid P, Fedosyuk R, Valikhnovskyi R, Gaide O, Kniazevych V, Saurat J-H. 2009. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) poisoning in Victor Yushchenko: Identification and measurement of TCDD metabolites. Lancet 374(9696):1179–1185.

Steinmaus C, Moore LE, Shipp M, Kalman D, Rey OA, Biggs ML, Hopenhayn C, Bates MN, Zheng S, Wiencke JK, Smith AH. 2007. Genetic polymorphisms in MTHFR 677 and 1298, GSTM1 and T1, and metabolism of arsenic. Journal of Toxicology and Environmental Health–Part A 70(2):159–170.

Steinmaus C, Yuan Y, Kalman D, Rey OA, Skibola CF, Dauphine D, Basu A, Porter KE, Hubbard A, Bates MN, Smith MT, Smith AH. 2010. Individual differences in arsenic metabolism and lung cancer in a case–control study in Cordoba, Argentina. Toxicology and Applied Pharmacology 247(2):138–145.

Stott WT, Johnson KA, Landry TD, Gorzinski SJ, Cieszlak FS. 1990. Chronic toxicity and oncogenicity of picloram in Fischer 344 rats. Journal of Toxicology and Environmental Health 30:91–104.

Suzuki KT, Katagiri A, Sakuma Y, Ogra Y, Ohmichi M. 2004. Distributions and chemical forms of arsenic after intravenous administration of dimethylarsinic and monomethylarsonic acids to rats. Toxicology and Applied Pharmacology 198(3):336–344.

Suzuki S, Arnold LL, Pennington KL, Chen B, Naranmandura H, Le XC, Cohen SM. 2010. Dietary administration of sodium arsenite to rats: Relations between dose and urinary concentrations of methylated and thio-metabolites and effects on the rat urinary bladder epithelium. Toxicology and Applied Pharmacology 244(2):99–105.

Swanson HI, Chan WK, Bradfield CA. 1995. DNA binding specificities and pairing rules of the Ah receptor, ARNT, and SIM proteins. Journal of Biological Chemistry 270(44):26292–26302.

Szyf M. 2007. The dynamic epigenome and its implications in toxicology. Toxicological Sciences 100(1):7–23.

Thompson DJ, Emerson JL, Strebing RJ, Gerbig CG, Robinson VB. 1972. Teratology and postnatal studies on 4-amino-3,5,6-trichloropicolinic acid (picloram) in the rat. Food and Cosmetics Toxicology 10:797–803.

Thornton AS, Oda Y, Stuart GR, Glickman BW, de Boer JG. 2001. Mutagenicity of TCDD in Big Blue transgenic rats. Mutation Research 478:45–50.

Timchalk C. 2004. Comparative inter-species pharmacokinetics of phenoxyacetic acid herbicides and related organic acids. Evidence that the dog is not a relevant species for evaluation of human health risk. Toxicology 200(1):1–19.

Turner BM. 1998. Histone acetylation as an epigenetic determinant of long-term transcriptional competence. Cellular and Molecular Life Sciences 54(1):21–31.

Vahter M, Concha G. 2001. Role of metabolism in arsenic toxicity. Pharmacology and Toxicology 89(1):1–5.

Valeri N, Vannini I, Fanini F, Calore F, Adair B, Fabbri M. 2009. Epigenetics, miRNAs, and human cancer: A new chapter in human gene regulation. Mammalian Genome 20:573–580.

van den Berg M, Birnbaum L, Denison MS, De Vito M, Farland W, Feeley M, Fiedler H, Hakansson H, Hanberg A, Haws L, Rose M, Safe S, Schrenk D, Tohyama C, Tritscher A, Tuomisto J, Tysklind M, Walker N, Peterson R. 2006. The 2005 World Health Organization re-evaluation of human and mammalian toxic equivalency factors for dioxins and dioxin-like compounds. Toxicological Sciences 93(2):223–241.

Van der Molen GW, Kooijman SALM, Slob W. 1996. A generic toxicokinetic model for persistent lipophilic compounds in humans: An application to TCDD. Toxicological Sciences 31(1):83–84.



The National Academies | 500 Fifth St. N.W. | Washington, D.C. 20001
Copyright © National Academy of Sciences. All rights reserved.
Terms of Use and Privacy Statement