TABLE 5-1 Grade A and B Recommendations with Committee Interpretations and Clarification Statements

Topic USPSTF Recommendation USPSTF Grade IOM Committee Interpretation

Alcohol misuse counseling The USPSTF recommends screening and behavioral counseling interventions to reduce alcohol misuse by adults, including pregnant women, in primary care settings. B Annual screening with approved screening instrument.
Anemia screening: pregnant women The USPSTF recommends routine screening for iron deficiency anemia in asymptomatic pregnant women. B Screening in each trimester.
Blood pressure screening The USPSTF recommends screening for high blood pressure in adults aged 18 and older. A Annual screening.
BRCA screening, counseling about The USPSTF recommends that women whose family history is associated with an increased risk for deleterious mutations in BRCA1 or BRCA2 genes be referred for genetic counseling and evaluation for BRCA testing. B Referral for genetic counseling and testing, if appropriate.
Breast cancer preventive medication The USPSTF recommends that clinicians discuss chemoprevention with women at high risk for breast cancer and at low risk for adverse effects of chemoprevention. Clinicians should inform patients of the potential benefits and harms of chemoprevention. B Medication provided if indicated.
Depression screening: adolescents The USPSTF recommends screening of adolescents (12–18 years of age) for major depressive disorder when systems are in place to ensure accurate diagnosis, psychotherapy (cognitive-behavioral or interpersonal), and follow-up. B Annual depression screening.
Depression screening: adults The USPSTF recommends screening adults for depression when staff-assisted depression care supports are in place to assure accurate diagnosis, effective treatment, and follow-up. B Annual depression screening.
Diabetes screening The USPSTF recommends screening for type 2 diabetes in asymptomatic adults with sustained blood pressure (either treated or untreated) greater than 135/80 mm Hg. B Annual screening.

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