emergency use authorization, 86

expiration of medications, 85, 88, 114-115, 116

goals for timely distribution, 7, 21, 58, 61

impact of time to detection on, 57-61

incubation period of anthrax and, 6-7, 46, 55-57, 61

mechanism of action, 33

recommendations for research, 19, 215

response to anthrax attacks of 2001, 56-57

salient issues, 41

storage of medications, 114

treatment regimen, 42, 133

See also Adherence to prophylactic antibiotic regimen; Antibiotic- resistant anthrax

Antibiotic-resistant anthrax concerns with predispensing strategies, 132-133, 134-135, 136

creation of, 5, 43, 132-133

definitions, 43n

flexibility of MCM system, 45, 46

implications for MCM planning, 5-6, 32, 43-46

laboratory testing for, 44b, 45n

threat of, 24, 43, 44b

Antitoxin strategies, 26, 33

Appropriateness of prepositioning strategies, 14, 15t, 199-202, 200t

Assessment of distribution and dispensing capacity

data from full-scale exercises, 162-163

in decision-aiding framework for prepositioning, 10b, 154b, 158-163

importance of, 10, 163

measures for, 10, 11, 25, 159-161, 164, 212

obstacles to, 10-11, 158, 163

recommendations for, 11, 164, 212

Assistant Secretary for Preparedness and Response, 108, 156

Association of State and Territorial Health Officials, 108

Aum Shinrikyo, 23

B

BioWatch Actionable Result, 59

BioWatch monitoring system, 35, 58-60

Brentwood postal facility, 56, 84

Business Executives for National Security, 77

C

Cached MCM

advantages, 95-97t

appropriateness and consequences of, 15t, 199-202, 200t

definition, 7, 8f, 29b, 93

determinants of effectiveness, 13

in educational institutions, 118-119

in hospitals and health care facilities, 26, 103-106

infrastructure needs, 95-97t

key features, 94, 95-97t

organizational entities needed for, 95-97t

potential health risks, 172

potential locations, 103

private sector participation, 107

recommendations for local jurisdictions, 14-16, 18b, 203, 211

role of community- and faith-based organizations, 117-118

See also Home storage of antibiotics; Personal stockpile; Workplace caches

Centers for Disease Control and Prevention

Cities Readiness Initiative, 7, 53b, 58, 61, 73



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