• Front Matter R1-R16

• 1 Introduction 1-4

• 2 Framing the Problem 5-16

• 3 Recruitment Challenges in Clinical Trials for Different Diseases and Conditions 17-30

• 4 Models for Public Engagement 31-38

• 5 Messages and Methods for Public Engagement 39-48

• 6 The Media 49-54

• 7 Novel Clinical Trial Designs 55-64

• 8 The Health System's Structure and Culture 65-74

• 9 Toward a Patient-Centered Strategy for Clinical Trials 75-84

• References 85-88

• Appendix A: Workshop Agenda 89-98

• Appendix B: The Clinical Trials Process 99-100

• Appendix C: Participant Biographies 101-124

" 6 The Media ." Public Engagement and Clinical Trials: New Models and Disruptive Technologies: Workshop Summary . Washington, DC: The National Academies Press, 2011 .

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