|
||||||||||||||||
|
||||||||||||||||
|
||||||||||||||||
|
| ||||||||||||||||||||||||||||||||
|
||||||||||||||||||||||||||||||||
Below are the first 10 and last 10 pages of uncorrected machine-read text (when available) of this chapter, followed by the top 30 algorithmically extracted key phrases from the chapter as a whole.
Intended to provide our own search engines and external engines with highly rich, chapter-representative searchable text on the opening pages of each chapter.
Because it is UNCORRECTED material, please consider the following text as a useful but insufficient proxy for the authoritative book pages.
Do not use for reproduction, copying, pasting, or reading; exclusively for search engines.
OCR for page 495
Appendix B
Agenda
The Science and Applications of Synthetic and Systems Biology
March 14-15, 2011
Keck Building, Room 100
500 Fifth Street, NW
Washington, DC
DAY 1: MONDAY, MARCH 14, 2011
8:00–8:30 am Registration and Continental Breakfast
8:30–8:45 am Welcoming Remarks
David Relman, M.D., Chair, and Jim Hughes, M.D.,
and Lonnie King, D.V.M., Vice-Chairs, Forum on
Microbial Threats
8:45–9:30 am Keynote Remarks
David Relman, Moderator
Synthetic Biology and Biodefense
Andrew Ellington, Ph.D., University of Texas at Austin
9:30–10:00 am Discussion
10:00–10:15 am Break
495
OCR for page 496
496 SYNTHETIC AND SYSTEMS BIOLOGY
SESSION 1: The Promise of Synthetic and Systems Biology for the
Understanding and Management of Infectious Diseases
Jesse Goodman, Moderator
10:15–10:45 am Synthetic biology, systems biology, and microbial threats
James J. Collins, Ph.D., Boston University
10:45–11:15 am A metabolic engineering platform for discovery and
production of new therapeutics
Greg Stephanopoulos, Ph.D., Massachusetts Institute of
Technology (MIT)
11:15–11:45 am Insights into pathogen-host interactions from systems
biology
Bernhard Palsson, Ph.D., University of California, San
Diego
11:45–12:15 pm Commercial applications of synthetic biology
David Berry, M.D., Ph.D., Flagship Ventures
12:15–12:45 pm Discussion
12:45–1:30 pm Lunch
SESSION 2: “The Basics” of Synthetic Biology:
Bottom-Up vs. Top-Down Approaches
George Poste, Moderator
1:30–2:00 pm Systems for synthetic biology
Hans Westerhoff, Ph.D., University of Manchester and
the VU University Amsterdam
2:00–2:30 pm Design and complexity
Herbert Sauro, Ph.D., University of Washington
2:30–3:00 pm DNA synthesis
George Church, Ph.D., Harvard University
3:00–3:30 pm Synthetic biology “from scratch”
Gerald Joyce, M.D., Ph.D., The Scripps Research
Institute
3:30–3:45 pm Break
OCR for page 497
497
APPENDIX B
3:45–4:15pm Protein engineering and high throughput immune
function analyses for the discovery of the next
generation of protein therapeutics
George Georgiou, Ph.D., University of Texas at Austin
4: 15–4:45 pm Synthesis and installation of genomes
Clyde Hutchison III, Ph.D., J. Craig Venter Institute
4:45–5:15 pm Access through refactoring: Rebuilding complex
functions from the ground up
Chris Voigt, Ph.D., University of California, San
Francisco
5:15–6:00 pm Discussion
6:00 pm Meeting Adjourns
DAY 2: TUESDAY, MARCH 15, 2011
8:45–9:15 am Continental breakfast
9:15–9:30 am Summary of Day One and Preview of Day Two: David
Relman, M.D., Chair, Forum on Microbial Threats
SESSION 3: Using Synthetic/Systems Biology
Approaches to Manage Biofilms
David Relman, Moderator
9:30–10:00 am Harnessing and controlling social activities of bacteria
E. Peter Greenberg, Ph.D., University of Washington
10:00–10:30 am Developing a synthetic biology device that detects
biofilm formation on indwelling catheters
Paul Freemont, Prof., Imperial College London
10:30–10:45 am Break
10:45–11:15am Novel approaches to combat biofilm drug tolerance
Kim Lewis, Ph.D., Northeastern University
11:15–11:45 am Engineering viruses to destroy biofilms
Timothy Lu, M.D., Ph.D., Massachusetts Institute of
Technology
OCR for page 498
498 SYNTHETIC AND SYSTEMS BIOLOGY
11:45–12:15 pm Discussion
12:15–1:00 pm Lunch
SESSION 4: Synthetic/Systems Biology Products and Platforms: Potential
for Novel Preventives, Diagnostics, and Therapeutics in Infectious Diseases
Kent Kester, Moderator
1:00–1:30 pm Engineering microbial metabolism for production of anti-
malarial drugs
Jay Keasling, Ph.D., University of California, Berkeley
1:30–2:00 pm Dynamics of clonal evolution: Immune system on a chip
Jim Heath, Ph.D., California Institute of Technology
2:00–2:30 pm Using systems biology to understand and develop more
effective vaccines
Bali Pulendran, Ph.D., Emory University
2:30–2:45 pm Break
2:45–3:15 pm HTP screening system based on synthetic genes and
proteins
Stephen Johnston, Ph.D., Arizona State University
3:15–3:45 pm Synthetic biology and the art of biosensor design
Chris French, Ph.D., University of Edinburgh
3:45–4:45 pm Open Discussion with Panelists, Forum Members, and
Audience
4:45–5:00 pm Wrap-up Discussion, Jim Hughes and David Relman
5:00 pm Meeting Adjourns
