project must be reviewed and approved by intramural scientific program staff or an extramural initial review group and by the appropriate Animal Care and Use Committee. The IAMC’s evaluation constitutes an additional level of scientific review, focusing on such factors as the appropriateness of the animal model, appropriateness of the numbers of animals, the availability of the animals, the degree of invasiveness of the procedures, and any unnecessary duplication. (NIH, unpublished)

Appointment of the IAMC is evidence that the NIH has determined that the conservation and care of chimpanzees requires additional oversight. Membership on the Interagency Animal Model Committee is restricted to federal employees from the Department of Health and Human Services (including the NIH, CDC, and FDA), Department of Veterans Affairs, and Department of Defense. The committee believes that assessment of potential future use of the chimpanzee would be strengthened and the process made more credible by establishing an independent oversight committee that uses the recommended criteria and includes public representatives as well as individuals with scientific expertise, both in the use of chimpanzees and alternative models, in areas of research that have the potential for chimpanzee use.



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