FDA

Food and Drug Administration

FNIH

Foundation for the National Institutes of Health

FTC

Federal Trade Commission

 

GSK

GlaxoSmithKline

 

HER2

human epidermal growth factor receptor 2

HIV

Human Immunodeficiency Virus

HPV

human papillomavirus

 

IGF

insulin-like growth factor

IIP

instantaneous inhibitory potential

IND

Investigational New Drug

IP

intellectual property

IRB

Institutional Review Board

I-SPY TRIAL

Investigation of Serial studies to Predict Your Therapeutic Response with Imaging And moLecular analysis

 

LCMV

lymphocytic choriomeningitis virus

 

MAPK

mitogen-activated protein kinase

MEK

mitogen-activated protein kinase kinase

MET

Methylnitronitrosoguanidine-HOS (Human osteosarcoma) Transforming gene

MTA

Material Transfer Agreement

mTORC1

mammalian target of rapamycin complex-1

 

NCDDG

National Cooperative Drug Discovery Groups

NCI

National Cancer Institute

NERF

non-exclusive royalty-free

NIAID

National Institute of Allergy and Infectious Diseases

NIH

National Institutes of Health

NOD

non-obese diabetic

 

OS

overall survival

 

PathCR

pathological complete response

PET

positron emission tomography

PFS

progression-free survival

PI3K

phosphatidylinositol 3-kinase

PPTP

Pediatric Preclinical Testing Program

 

R&D

research and development



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