Appendix A

Agendas for Public Meetings

MEETING 1
Committee on Breast Cancer and the Environment:
The Scientific Evidence, Research Methodology, and Future Directions

The Keck Center of the National Academies
Washington, DC

Wednesday, April 14, 2010

10:45 a.m. Introductory Remarks

Irva Hertz-Picciotto, Ph.D.
Chair, Committee on Breast Cancer and the Environment: The Scientifc Evidence, Research Methodology, and Future Directions


Introductions by committee members and meeting attendees



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Appendix A Agendas for Public Meetings MEETING 1 Committee on Breast Cancer and the Environment: The Scientific Evidence, Research Methodology, and Future Directions The Keck Center of the National Academies Washington, DC Wednesday, April 14, 2010 10:45 a.m. Introductory Remarks Irva Hertz-Picciotto, Ph.D. Chair, Committee on Breast Cancer and the Environment: The Scientific Evidence, Research Methodology, and Future Directions Introductions by committee members and meeting attendees 347

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348 BREAST CANCER AND THE ENVIRONMENT 11:00 a.m. Study Context and Goals, Sponsor Perspective Amelie Ramirez, Dr.P.H. Member, Susan G. Komen for the Cure Scientific Advisory Board Director, Institute for Health Promotion Research University of Texas Health Science Center at San Antonio Questions and discussion with the committee 12:00 p.m. Lunch 12:45–2:30 p.m. Comments from Breast Cancer Research and Advocacy Organizations • hat are their concerns and priorities regarding W environmental risk factors for breast cancer? • hat do they want to make sure the committee is W aware of? • What do they hope the study will contribute? Organizations Planning to Present Avon Foundation: Marc Hurlbert, Ph.D. Breast Cancer Fund: Janet Gray, Ph.D. Breast Cancer Research Foundation: Mary Beth Terry, Ph.D. (phone) National Breast Cancer Coalition: Fran Visco National Institutes of Health Breast Cancer and Environment Activities: Gwen Collman, Ph.D. Young Survival Coalition: Marcia Stein 2:45 p.m. Break 3:00–4:30 p.m. Introduction to Issues in Studying Breast Cancer and the Environment Presentations by Committee Members 4:30 p.m. Opportunity for Individual Public Comment Kathleen Burns, Ph.D. (phone) Director, Sciencecorps Lexington, MA

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349 APPENDIX A William Mimiaga, Major, USMC (RET) (phone) California Michael Partain (phone) The Few, The Proud, The Forgotten James Fontella (phone) Shelby Township, MI 5:00 p.m. Adjourn Open Session MEETING 2 Committee on Breast Cancer and the Environment: The Scientific Evidence, Research Methodology, and Future Directions The Hyatt Regency San Francisco San Francisco, CA Tuesday, July 6, 2010 2:00 p.m. Introductory Remarks Irva Hertz-Picciotto, Ph.D. Chair, Committee on Breast Cancer and the Environment: The Scientific Evidence, Research Methodology, and Future Directions Introductions by committee members and meeting attendees Opportunity for Sponsor Comment Amelie Ramirez, Dr.P.H. Member, Susan G. Komen for the Cure Scientific Advisory Board Director, Institute for Health Promotion Research University of Texas Health Science Center at San Antonio

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350 BREAST CANCER AND THE ENVIRONMENT 2:15 p.m. Role of Animal Models in Studying Environmental Factors for Breast Cancer Helmut Zarbl, Ph.D. Professor, University of Medicine and Dentistry of New Jersey and Robert Wood Johnson Medical School Questions and discussion with the committee 3:00 p.m. Role of Stem Cells in Environmental Risks for Breast Cancer Zena Werb, Ph.D. Professor of Anatomy University of California, San Francisco Questions and discussion with the committee 3:45 p.m. Linking Prenatal and Neonatal Exposures to Breast Cancer Risks Dimitrios Trichopoulos, M.D. Professor of Cancer Prevention and Professor of Epidemiology Harvard School of Public Health Questions and discussion with the committee 4:30 p.m. General Discussion as Needed 4:45–5:25 p.m. Comments from Breast Cancer Research and Advocacy Organizations • hat are their concerns and priorities regarding W environmental risk factors for breast cancer? • hat do they want to make sure the committee is W aware of? • hat do they hope the study will contribute? W Organizations Planning to Present American Cancer Society: Michael Thun, M.D. Breast Cancer Action: Kim Irish, J.D. Breast Cancer Fund: Nancy Buermeyer Zero Breast Cancer: Janice Barlow 5:25 p.m. Adjourn Open Session

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351 APPENDIX A Wednesday, July 7, 2010 8:30 a.m. Introductory Remarks Irva Hertz-Picciotto, Ph.D. Chair, Committee on Breast Cancer and the Environment: The Scientific Evidence, Research Methodology, and Future Directions Introductions by committee members and meeting attendees 8:45 a.m.– Reaching Conclusions About Carcinogenicity 12:00 p.m. 8:45 a.m. Weighing Evidence from NTP Bioassays John Bucher, Ph.D. Associate Director, National Toxicology Program Questions and discussion 9:30 a.m. Evaluation of Human and Experimental Evidence to Identify Cancer Hazard and Estimate Risk Kathryn Z. Guyton, Ph.D., D.A.B.T. Toxicologist, National Center for Environmental Assessment Office of Research and Development, U.S. EPA Questions and discussion 10:15 a.m. Identifying Breast Carcinogens at IARC Vincent James Cogliano, Ph.D. Head, IARC Monographs Program Questions and discussion 11:00 a.m. How Toxicology Can Advance Breast Cancer Prevention by Informing Chemicals Policies and Epidemiologic Study Design Ruthann Rudel, M.S. Director of Research, Silent Spring Institute Questions and discussion 11:45 a.m. General discussion as needed 12:00 p.m. Lunch

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352 BREAST CANCER AND THE ENVIRONMENT 1:00–2:00 p.m. Introduction to Issues in Studying Breast Cancer and the Environment, Committee Presentations Continued 1:00 p.m. An Epidemiologic Perspective on Environmental Risk Factors Peggy Reynolds, Ph.D. Senior Research Scientist, Cancer Prevention Institute of California 1:30 p.m. Breast Cancer and Environment Research Centers: Experience and Plans Robert Hiatt, M.D. Deputy Director, Helen Diller Family Comprehensive Cancer Center 2:00–3:00 p.m. Initiatives on Breast Cancer and the Environment: Research Gaps and Policy Proposals 2:00 p.m. The California Breast Cancer Research Program’s Special Research Initiatives on Environment and Disparities Marion (Mhel) Kavanaugh-Lynch, M.D., M.P.H. Director, California Breast Cancer Research Program Questions and discussion 2:30 p.m. Breast Cancer and Chemicals Policy Project Sarah Janssen, M.D., Ph.D., M.P.H. Senior Scientist, Natural Resources Defense Council and Megan Schwarzman, M.D., M.P.H. Research Scientist, Berkeley Center for Green Chemistry School of Public Health, University of California, Berkeley Questions and discussion 3:00 p.m. Opportunity for Individual Public Comment Nancy Bellen, Santa Rosa, CA Marika Holmgren, Breast Cancer Survivor Susan Braun, Executive Director, Commonweal 3:30 p.m. Adjourn Open Session

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353 APPENDIX A MEETING 3 Committee on Breast Cancer and the Environment: The Scientific Evidence, Research Methodology, and Future Directions The Keck Center of the National Academies Washington, DC Wednesday, September 15, 2010 2:15 p.m. Introductory Remarks Irva Hertz-Picciotto, Ph.D. Chair, Committee on Breast Cancer and the Environment: The Scientific Evidence, Research Methodology, and Future Directions Introductions by committee members and meeting attendees Opportunity for Sponsor Comment Amelie Ramirez, Dr.P.H. Member, Susan G. Komen for the Cure Scientific Advisory Board Director, Institute for Health Promotion Research University of Texas Health Science Center at San Antonio 2:30 p.m. Environmental Pollution and Breast Cancer: Adding Epidemiological Studies to Biological Evidence Julia G. Brody, Ph.D. Executive Director Silent Spring Institute Questions and discussion with the committee 3:15 p.m. Early Life Exposures and Breast Cancer Risk Michele R. Forman, Ph.D., M.S. Professor, Department of Epidemiology University of Texas MD Anderson Cancer Center Questions and discussion with the committee

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354 BREAST CANCER AND THE ENVIRONMENT 4:00 p.m. Windows of Susceptibility to Breast Cancer and Environmental Exposures Jose Russo, M.D. Director, Breast Cancer Research Laboratory and NCI-NIEHS Breast Cancer and the Environment Research Center Fox Chase Cancer Center Questions and discussion with the committee 4:45 p.m. General Discussion as Needed 5:00 p.m. Opportunity for Individual Public Comment Rebecca Shaloff, Washington, DC Victoria Pavelko, Reston, VA Heather Rogers, Alexandria, VA 5:30 p.m. Adjourn Open Session