WHO immediately*, i.e. within 24 hrs after having carried out the assessment of public health information related to the event. Such notification will include details of any health measure employed in response to the event as well as accurate and sufficiently detailed public health information available, including case definitions, laboratory results, and number of cases and deaths.” “In addition to notification and consultation, state parties are required to inform WHO within 24 hrs of receipt of evidence of public health risks occurring outside their territory that may cause international disease spread.” IHR (2005) defines immediately as: within 24 hrs. http://www.who.int/ihr/about/10things/en/index.html

xiv FAO Animal Health Manual on the preparation of national animal disease emergency preparedness plans. http://www.fao.org/DOCREP/004/X2096E/X2096E00.htm

xv Active surveillance includes activities in which those responsible for human and animal health identify new cases of disease (case finding) and/or involve interviewing patients, reviewing medical records to detect cases or after index case has been reported.

Passive surveillance includes activities in which available data on reportable diseases is used or reporting is mandated or requested by those responsible for human and animal health. (Leon Gordis, Epidemiology Second Edition). WHO Recommended Surveillance Standards, Second edition, http://www.who.int/csr/resources/publications/surveillance/whocdscsrisr992.pdf

xvi Events constituting a PHEIC are assessed by country using the decision instrument in Annex 2 of IHR. http://www.who.int/ihr/9789241596664/en/index.html

xvii OIE reportable diseases http://www.oie.int/eng/maladies/en_classification2010.htm?eld7

xviii WHO IHR Monitoring Framework for monitoring Progress in the implementation of IHR Core Capacities in State Parties. Annual Data Collection Tool (2010). http://www.who.int/ihr/checklist/en/index.html

xix OIE World Animal Health Information System (WAHIS). http://www.oie.int/ENG/info/en_info.htm

xx Immediate reporting of EDPs as required by CSTE and referenced by CDC for guidelines regarding nationally notifiable diseases. http://www.cste.org/dnn/LinkClick.aspx?fileticket=7CCxM20JUGg%3dtabid=36∣=1496 http://www.who.int/ihr/about/10things/en/index.html

xxi Events constituting a PHEIC are assessed by country using the decision instrument in Annex 2 of the IHR. http://www.who.int/ihr/9789241596664/en/index.html

xxii OIE reportable diseases http://www.oie.int/eng/maladies/en_classification2010.htm?eld7

xxiii WHO/OIE standards http://www.who.int/ihr/IHR_Monitoring_Framework_Checklist_and_lndicators.pdf

xxiv Optimum conditions include adherence to appropriate BS&S regulations, cold-chain maintenance, and universal precautions.

xxv http://www.who.int/ihr/IHR_Monitoring_Framework_Checklist_and_lndicators.pdf

xxvi Cost is the combined metric of multiple sustainment topics, including but not limited to: operations, maintenance, technology, infrastructure, knowledge, skills, abilities, educational, logistics, regulatory, cultural) etc. Operations cost is for biosecurity and collection facility. “Maintenance costs” is for biosecurity and collection facility.

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