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Appendix B
Computation of Average Daily Dose
The Average Daily Dose from all exposures to ADDD = Contaminant × SA × PC × BAF × F × D1 × D 2 × C
D
BW × AP
reclaimed water (ADDRW ) can be estimated using the
following equation (modified from Hutcheson et al.,
where
1990):
ContaminantR = Concentration of chemical in
ADDRW = ADDR + ADDD + ADDI
reclaimed water (mass/volume),
SA = Skin surface area in contact with
The Average Daily Dose from ingestion of the
the surface water during the
reclaimed water (ADDR) can be estimated using the
period of exposure (area),
following equation (modified from Hutcheson and
PC = Permeability constant (volume/
Martin, 1992):
time × area),
D1 = Average duration of each
ADDR = Contaminant R × VI × BAF D 2 × C
BW × AP
exposure event (time/event),
D2 = D uration of the exposure period
(time),
where
BAF = Bioavailability adjustment
ContaminantR = Concentration of chemical in factor,
reclaimed water (mass/volume), F = Number of exposure events
VI = Daily volume of reclaimed during the exposure period
water ingestion (mass/volume), divided by the number of days
BAF = Bioavailability adjustment in the exposure period (events/
factor, time),
D2 = D uration of the exposure D1 = Average duration of each
period (time), exposure event (time/event),
BW = Average body weight (e.g., D2 = D uration of the exposure period
70 kg), (time),
AP = Averaging period (time), BW = Average body weight (e.g.,
C = Appropriate units conversion 70 kg),
factor. AP = Averaging period (time),
C = Appropriate units conversion
The Average Daily Dose from dermal contact with factor.
reclaimed water (ADDD) can be estimated using the
following equation:
249
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250 APPENDIX B
The Average Daily Dose from inhalation of con- F = Number of exposure events
taminants in reclaimed water (ADDI) can be estimated during the exposure period
using the following equation: divided by the number of days
in the exposure period (events/
ADDI = Contaminant × VR × BAF × F × D1 × D 2 × C time),
I
BW × AP
D1 = Average duration of each
where exposure event (time/event),
D2 = D uration of the exposure period
ContaminantR = Concentration of chemical in
(time),
reclaimed water (mass/volume),
BW = Average body weight (e.g.,
VR = Daily respiratory volume during
70 kg),
the period of exposure (volume/
AP = Averaging period (time),
time),
C = Appropriate units conversion
BAF = Bioavailability adjustment
factor.
factor,