1- What high-containment biological research facilities exist in your country?

In Brazil, only those laboratories conducting research related to public health, agriculture, and genetically modified organisms (GMOs) are subject to government regulation. There is no oversight or evaluative mechanism for laboratories, high-containment or otherwise, that are established at public or private universities for research activities with biological agents (other than GMOs). So, the answer here refers to public health, agriculture, and GMO laboratories only.

There are a total of 12 BSL-3 laboratories under the responsibility of the Ministry of Health and 8 BSL-3 laboratories under the responsibility of the Ministry of Agriculture (Table E1-1). Brazil currently has no BSL-4 laboratories, although there has been ongoing discussion about building one.

Table E1-1 List of known BSL-3-capable laboratories and microorganisms in Brazil.

Item Institution Microorganism Risk Classa Lab BSL
1 Universidade Federal do Amazonas
Laboratório de Genética Animal
Aspergillus
M. tuberculosis MDR
2
3
BSL2
BSL-3
2 Fiocruz – IOC
Laboratorio de AIDS e Imunologia Molecular
HIV 3 BSL-3
3 LACEN – CE
Laboratório de Microbiologia
Micobacterium tuberculosis MDR
Yersinia pestis
Burkholderia pseudomallei
3
3
3
BSL-3
4 Embrapa Suínos e Aves - SC
Lab. Virologia/ Laboratório de Sanidade
Avian Flu virus, New Castle virus,
virus of respiratory and
reproductive syndrome in swine
(PRRS), Mycobacteria
3,4 BSL1
BSL2
BSL-3b
5 Merial Saúde Animal LTDA - SP
Departamento Qualidade - Segurança Biológica
Brucella abortus
FMDV
3
4
BSL-3
6 FIOCRUZ – IOC
Laboratório de Biologia e Parasitologia de Mamíferos
Silvestres Laboratórios
T. cruzi
Leishmanias
2
3
BSL-3
7 Instituto Nacional de Salud - Peru M. tuberculosis MDR
Leishmania
Yellow fever virus
Hepatitis, A,B,C virus
3
3
2
2
BSL-3
8 Universidade Federal do Rio de Janeiro
Departamento de Diagnóstico Oral e Patologia
HIV 3 BSL-3
9 Embrapa Gado de Corte - MS
Lab. Sanidade Animal e Virologia
FMDV
Brucella spp.
Mycobacterium bovis
4
3
3
BSL1
BSL2
BSL-3b
10 Universidade de Sᾶo Paulo
Núcleo de Pesquisas em Raiva do Lab. Virologia Clínica e
Molecular do Depto Microbiologia
Arbovirus

Hantavirus
3

3
BSL-3
BSL2
11 LANAGRO/SP
Setor de Sanidade Aviária
Avian Influenza virus
Newcastle virus
4
4
BSL-3
12 Universidade Federal de Pernambuco

Departamento de Antibióticos/Laboratórios de Fármacos e
Processos microbianos e laboratório de Processos
Fermentativos
Escherichia coli
Chlostridium botulinum
Coccidioides immitis
Penicillium spp.
Aspergillus spp.
Candida spp
Salmonella spp.
2
2
3
2
2
2
2
BSL1
BSL2
BSL-3
13 Fundaçᾶo de Medicina Tropical do Amazonas

Lab. Virologia
M. tuberculosis MDR
Hepatitis virus
Dengue virus
Oropoche- and Mayaro virus
3
2
2
4
BSL2
BSL-3
14 Fiocruz
Centro de Pesquisas Aggeu Magalhᾶes
Biotério Central
Yersinia pestis
Hantavirus
3
3
BSL2
BSL-3
15 Fiocruz - Centro de Pesquisas Aggeu Magalhᾶes
Lab. serviço de referencia em peste
Yersinia pestis 3 BSL-3
16 UNESP - Faculdade de Ciências Farmacêuticas
Araraquara
Depto Análises Clínicas
HIV
M. tuberculosis MDR
Hepatitis virus
3
3
2
BSL2
BSL-3


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