Table E8-2 Number of sites with BSL-4 laboratories (December 2007)a
|BSL-4||5||2* (Now 1)||3||0|
There is now only one private BSL-4 site.
SOURCE: Contains Parliamentary information licensed under the Open Parliament Licence v1.0.
Of the eight government sites, five can operate at BSL-4 for human pathogens (ACDP4), although only four actually operate at this level, and three at BSL-4 for animal pathogens (SAPO4). Seven sites have facilities to work with infected animals.5 The facilities at each site vary in size from a single room to multiple suites or even individual buildings of BSL-4 laboratories.6 All BSL-4 facilities are located in the South East of England, ranging from rural settings to suburban areas and cities (there are three BSL-4 sites in or near London).7 In addition to these BSL-4 laboratories for research and diagnostics, there are also two High Security Disease Isolation Units (HSDUs) for the care of patients with viral haemorrhagic fevers, such as Ebola or Lassa. One is in Coppetts Wood, London, which would also be used for a postmortem requiring BSL-4, and the other is under development at the Royal Victoria Infirmary, Newcastle.8
Table E8-3 Details of UK BSL-4 laboratories, covering data for 2010a
|Government||Defence science and technology laboratory (Dstl). porton Down. Wiltshire||Ministry of Defence||Two BSL-4 laboratories (335 m2 total)||R&D into protective measures against biological weapons|
|Government||Centre for Emergency prepa redness and Response. Health protection Agency (HPA). porton Down. Wiltshire||Department of Health||Two BSL-4 units (59 m2; and 46 m )||Diagnosis and research on viruses including Lassa. Ebola. Marburg and other haemorrhagic fever viruses.|
|Government||Health Protection Agency (HPA). Collndale. London||Department of Health||One BSL-4 unrt (30 m2)||Applied diagnostic R&D. and diagnostic services for Herpes B; viral haemorrhagic fever infections (Lassa fever, Ebola, Marburg, Congo-Crimean haemorrhagic fever); avian influenza; and SARS|
|Government||National Institute for Biological Standards and Control (NIBSC), Department of Health, Potters Bar. Hertfordshire||Department of Health and Home Office||Two BSL-4 units (each 59 m2)||Activities related to development of assays and testing of reagents Including: highly pathogenic Influenza virus — reagent development; Bacillus anthracis — vaccine testing, reagent development, development of in vitro assays; Yersinia pestis — molecular structural work; Botulinum toxins (serotypes A-G) - control, standardisation and assay development for vaccines and anti-toxins|