image

FIGURE J-1 Comprehensive protocol for live-animal live-fire tests.

COMPREHENSIVE PROTOCOL FOR ASSESSING DAMAGE TO TISSUES REMOTE FROM THE SITE OF BLUNT TRAUMA

It is important to maintain surveillance of animals for as long as feasible after the live-fire exposure. Previous studies under NATO protocols lasted for a little as 30 min. Other studies have observed animals up to 8 hr before termination. The humane guidance has been to terminate the animals before they recover from the anesthesia, and this is recommended if the animals have received substantial trauma. Under conditions that produce minimal trauma—for example, EKG, EEG, and respirations—and no hemoptisis, permission to observe the animals longer term should be pursued, as the resulting medical information would be crucial for development of personnel protective armor.

Theory and model studies cannot predict long-term consequence for blunt trauma to live organisms.

Pathology

Conventional gross and microscopic histopathology studies should be routine at the termination of animal studies. Measurements of blood-brain barrier



The National Academies | 500 Fifth St. N.W. | Washington, D.C. 20001
Copyright © National Academy of Sciences. All rights reserved.
Terms of Use and Privacy Statement