Medical Monitoring Project

MMP was initiated by CDC in 2005 in response to the Institute of Medicine (IOM) report Measuring What Matters: Allocation, Planning, and Quality Assessment for the Ryan White CARE Act, which described a need for representative data on the care and preventive service needs of individuals with HIV in the United States (CDC, 2012e; IOM, 2004). MMP utilizes a repeated (annual) cross-sectional design to obtain data from a national probability sample of HIV-diagnosed adults in care to

  • describe the clinical and virologic status of these persons;
  • describe the prevalence of comorbidities related to HIV disease;
  • describe HIV care and supportive services received and the quality of such services; and
  • identify met and unmet needs for HIV care and prevention services to inform prevention and care planning groups, health care providers, and other stakeholders (CDC, 2012c).

MMP is the only study since HCSUS (Bozzette et al., 1998; RAND, 2011) that is designed to be nationally representative of HIV-diagnosed adults in care in the United States. Whereas MMP employs a cross-sectional design, however, HCSUS was a prospective study that followed a cohort of individuals in care for HIV over time (RAND, 2011). MMP is conducted through cooperative agreements between CDC’s Division of HIV/AIDS Prevention-Surveillance and Epidemiology and state and local health departments in participating MMP project areas (CDC, 2012c).

Current Sampling Methodology

MMP uses three-stage, probability proportionate to size sampling for the selection of (1) project areas, (2) facilities that provide outpatient HIV medical care in selected project areas, and (3) HIV-infected adults who receive medical care at selected facilities (Figure 3-1). A similar sampling methodology was used in HCSUS to identify a cohort of people with HIV in care. The national population of inference for each MMP data collection cycle is HIV-infected adults age ≥18 years who received care from known providers of HIV medical care in the United States during a predefined population definition period (PDP).2 The PDP has been January 1 through


2For local estimates in MMP project areas, the population of inference is HIV-infected adults who received care from known providers of HIV care in the project area during the population definition period (CDC, 2012c).

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