applying its sciences to the most important of today’s problems in energy, health, and the environment. The isotopes program under the auspices of that office is expected to benefit rapidly from new innovations and developments. NSAC and its subcommittees have provided insightful reports that constitute a roadmap for the revitalized isotopes program. This advice is timely, coming when important decisions must be made. The committee sees these developments as an excellent example of how society’s investments in nuclear physics can help resolve difficult challenges that face the nation.