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Appendix Symposium Agenda August 23-26, 1988 Australian National University Canberra, Australia TUESDAY, AUGUST 23, 5:00 P.M. Welcome and Opening Remarks Wayne Holtzman (President, IUPsyS) University of Texas Austin, Texas, U.S.A. L.W. Nichol, Vice Chancellor, Australian National University, Canberra, Australia Roger Russell (Australian Workshop Coordinator), The Flinders University, Bedford Park, S.A., Australia Pamela Ebert Flattau (U.S. Workshop Coordinator), National Research Council, Washington, D.C., U.S.A. Keynote Address: Peter Spencer, Center for Research on Occupational and Environmental Toxicology, Oregon Health Sciences University, U.S.A. 415
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416 APPENDIX WEDNESDAY, AUGUST 24, 8:30 A.M. Opening Remarks: Wayne Holtzman, University of Texas, U.S.A. SESSION I Assessment of Neurobehavioral Tests Now in Use CHAIR: George Singer, Latrobe University, Australia Helena Hanninen, Institute of Occupation Health, Helsinki, Finland Ann Williamson, National Institute of Occupational Health and Safety, Sydney, Australia W. Kent Anger, National Institute for Occupational Safety and Health, Cincinnati, Ohio, U.S.A. "Methods in Behavioral Toxicology: Current Test Batteries and Need for Further Development" "The Current Status of Test Development in Neurobehavioral Toxicology" "Human Neurobehavioral Tests That Have Identified Effects of Both Short- and Long-Term Chemical Exposures" DISCUSSANT: J. Graham Beaumont, University of Swansea, U.K. 11:00 A.M. General Discussion 2:00 P.M. SESSION II Assessment of Animal Models: What Has Worked and What Is Needed CHAIR: Roger Russell, The Flinders University, Australia Hanna Michalek, Instituto Superiore di Sanita, Rome, Italy "Neurochemical Tests for Assessment of Neurotoxicity of a Cholinesterase Inhibitor in Senescent Rats: Animal Model for Alzheimer's Treatment?" David Overstreet, The Flinders "Animal Models of Dementia: Relevance University, Bedford Park, S.A., Australia of Testing to Neurobehavioral Toxicology" Deborah Cory-Slechta, University of Rochester, Rochester, New York, U.S.A. Beverly Kulig, Medical Biology Laboratory TNO, Rijswick, The Netherlands "Bridging Experimental Animal and Human Behavioral Toxicology Studies" "Methods and Issues in Evaluating the Effects of Organic Solvents on Nervous System Function" DISCUSSANT: Robert MacPhail, U.S. Environmental Protection Agency, U.S.A. 4:30 P.M. General Discussion
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APPENDIX 417 THURSDAY, AUGUST 25, 8:30 A.M. Opening Remarks: Andrew Pope, National Research Council, U.S.A. SESSION III Chemical Time Bombs: Environmental Causes of Neurodegenerative Diseases CHAIR: Robert MacPhail, U.S. Environmental Protection Agency, U.S.A. Gerhard Winneke, Institute of Environmental Hygiene, Dusseldorf, West Germany Deborah C. Rice, Health and Welfare Canada, Ontario, Canada Norman Krasnegor, National Institute of Child Health and Human Development, Bethesda, Maryland, U.S.A. Roger Russell, The Flinders University, Bedford Park, S.A., Australia "Neuropsychological Toxicity of Environmental Chemicals: Clinical and Subclinical Aspects" "The Health Effects of Environmental Lead Exposure: Closing Pandora's Box" "On the Identification and Measurement of Chemical Time Bombs: A Behavior Development Perspective" "Neurobehavioral 'Time Bombs': Their Nature and Their Mechanisms" DISCUSSANT: Peter Spencer, Center for Research on Occupational and Environmental Toxicology, Oregon Health Sciences University, U.S.A. 11:00 A.M. General Discussion 2:00 P.M. SESSION IV Behavioral Aspects of Neurotoxicity: Regional Issues CHAIR: W. Kent Anger, National Institute for Occupational Safety and Health, U.S.A. Liang You-xin, Shanghai Medical University, The People's Republic of China V.B. Saxena, P.P.N. College, Kanpur, India R. Gilioli, University of Milan, Italy "The Development and Perspective of Neurobehavioral Toxicity Tests in China" "Regional Issues in the Late Development of Neurobehavioral Toxicity Tests" "Regional Issues in the Development of Neurobehavioral Toxicity Tests" DISCUSSANT: Ann Williamson, National Institute of Occupational Safety and Health, Australia 4:30 P.M. General Discussion
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418 FRIDAY, AUGUST 26, 9:00 A.M. Opening Remarks: Pamela Ebert Flattau, National Research Council, U.S.A. SESSION V Recommendations for Further Research and Testing Robert MacPhail, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, U.S.A. Anders Iregren, National Board of Occupational Safety and Health, Solna, Sweden Bernard Weiss, University of Rochester, Rochester, New York, U.S.A. APPENDIX "Environmental Modulation of Neurobehavioral Toxicity" "Computerized Performance Testing in Neurotoxicology: Why, What, How and Where To? The SPES Example" "The Scope and Promise of Behavioral Toxicology" 11:00 A.M. Concluding Remarks: Roger Russell, The Flinders University, Australia