engineering teams that support microbial genome research in the Genome Sequencing and Analysis Platform at the Broad Institute. Ms. Wortman has worked as a scientist and manager in the field of genomic research for the past decade, coordinating the work of scientists and engineers in both corporate and academic settings. Her areas of expertise are genome annotation, comparative genome analysis, bioinformatics tool development, and large-scale data management. Additionally, she has made significant contributions to the published genome analyses of the fruit fly, human, mouse, and mosquito as well as multiple pathogenic fungi and parasites. Prior to joining the Broad Institute, Ms. Wortman was the associate director of bioinformatics at the Institute for Genome Sciences at the University of Maryland, School of Medicine, where she was the co–principal investigator of the Human Microbiome Project’s Data Analysis and Coordination Center and the Aspergillus Genome Database project. That followed 5 years at The Institute for Genomic Research (TIGR) at JCVI, where she was responsible for the annotation and analysis of all eukaryotic genome projects and contributed to infrastructure and tool development for early metagenomics projects.

Vincent B. Young, Ph.D., M.D., is an associate professor in the Department of Internal Medicine, Infectious Diseases Division, and the Department of Microbiology and Immunology at the University of Michigan Medical School. His research is directed at understanding the role of bacteria that inhabit the gastrointestinal tract and how they influence the health status of the host. Researchers in Dr. Young’s lab study the role of what would traditionally be considered “pathogenic bacteria” in gastrointestinal (GI) illness. In addition, they also examine how the population structure of indigenous GI microbiota can influence host-pathogen interaction and how changes in the community structure of indigenous microbiota can lead to pathogenic states. This research is being conducted both with material from human subjects and with animal models of disease. Dr. Young received his B.S. from the Massachusetts Institute of Technology and his M.D. and Ph.D. from Stanford University. He completed his clinical training in internal medicine and infectious diseases at Massachusetts General Hospital.

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