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Suggested Citation:"9 Future Research Directions." National Research Council. 2012. The Continuing Epidemiological Transition in Sub-Saharan Africa: A Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13533.
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9

Future Research Directions

The presentations and discussions in the workshop highlighted the importance of improving our understanding of the status and effects of the epidemiological transition in sub-Saharan Africa. The importance and immediacy of the issue was framed by Barthélémy Kuate Defo, who pointed out at the offset of the workshop that (a) since the 1960s, when most countries in sub-Saharan Africa achieved their independence, many contextual changes have affected the epidemiological landscape of the continent and the sub-Saharan African region; (b) urbanization, gross domestic product per capita, improved sanitation and water access, improved per capita agricultural production, improved telecommunications, increases in the number of physicians per 1,000 inhabitants, medical advances, and improved nutrition and living standards are major changes that have taken place in sub-Saharan Africa which have led to improvements in survival rates and substantial gains in life expectancy at birth, paving the way for the ongoing epidemiological transition in sub-Saharan African countries; (c) prospects for durable reductions in mortality are hampered by the high prevalence of communicable and preventable diseases; and (d) the data needed to understand the changes in the epidemiological landscape are thin in most countries in the region.

In the discussion on future directions it was pointed out that the importance of the issue and the paucity of data in sub-Saharan Africa lead to a situation in which estimates of population health parameters must be made but they tend to be made using whatever data are available as inputs to the increasingly sophisticated models that have been developed. These available data are usually at the global level, and the consequence is that national estimates for countries in sub-Saharan Africa tend to derived from global estimates. As better data become available, national estimates should contribute to the global estimates rather than vice versa, as is now the case.

The presentations and discussions at the workshop identified a need to help countries strengthen their health-information systems so that within-country data become the source of information and country figures can be fed into global estimates. In the face of health transitions it is necessary to measure not only health status but also rates of change, implying that within-country data cycles need to be put into operation on an ongoing basis. This is a prerequisite for ensuring a continuous supply of timely health information, rather than forcing analysts to rely on a series of random snapshots.

In the discussion on the national and local-area data needed to capture the epidemiological transition in African countries, workshop participants emphasized the importance of obtaining complete and timely registration of all births and deaths at the national level, including medical certification of the cause of death. However, for both logistical and economic reasons, it is unlikely that near-complete individual registration of births and deaths will be widely implemented in sub-Saharan African countries any

Suggested Citation:"9 Future Research Directions." National Research Council. 2012. The Continuing Epidemiological Transition in Sub-Saharan Africa: A Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13533.
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time in the near future. Thus it will be important to consider what Alan Lopez and others referred to as the “best-buy” strategies for health data in sub-Saharan Africa.

Discussing the choice of data sources, the conferees concluded that it would be useful to combine a variety of sources with different strengths. Such an approach will require research on the quality of various data sources in order to understand which sources are complementary and which are viable in a particular national context and over time. In evaluating the data sources researchers should consider such factors as the size and diversity of a country; the nature and coverage of the country’s health system; the local costs of relevant items such as wages, travel, and communications; and which data strategies have been more or less successful in a particular locality.

One particularly useful resource for informing the design of data-gathering systems for tracking epidemiological transition is AusAID’s Health Information Systems Knowledge Hub (HISHUB; http://www.uq.edu.au/hishub/) at the University of Queensland. Although this system was designed primarily for Asian and Pacific countries, the principles it lays out should translate well to sub-Saharan Africa. According to HISHUB, the minimum data set for understanding epidemiological transitions in order to inform health transitions includes:

1.  Reliable unbiased documentation of age-and sex-specific mortality, including the major causes of deaths in the population (civil registration with vital statistics and sentinel or sample mortality surveillance systems with verbal autopsy). Several sources of data on causes of death should be considered. Research should focus on means for obtaining physician-certified coverage of all deaths (at least 90 percent) in a country with cause-of-death coding of reasonable quality; the establishment of systems to collect such data has proved elusive for low-income countries as well as for many middle-income countries and will potentially require decades to achieve. In the meantime, the use of the World Health Organization Health Metrics Network and others interim data sources should be explored. Such interim data sources could include sentinel (urban and rural) demographic surveillance sites and, where possible, statistically representative sample registration sites with verbal autopsy on all deaths. It was suggested that designing, funding, and implementing these interim measures within one to two years would be an attainable goal.

2.  Periodic documentation of exposure to the top 10 major risk factors of mortality by age and sex (via periodic population-based surveys). Concerning this issue, it was noted that there are standard adapted survey instruments for each risk factor (smoking, nutrition, high blood pressure, obesity, HIV serostatus, solid fuel smoke exposure, etc.) but that these are rarely assembled into an omnibus national sample survey. Future research strategies should include an extension of the Health Metrics Network and the Household Survey Network in order to promote greater integration and more strategic scheduling of national household surveys.

3.  Periodic documentation of the effective coverage of key preventive and curative health interventions aimed at the aboce causes and risk factors

Suggested Citation:"9 Future Research Directions." National Research Council. 2012. The Continuing Epidemiological Transition in Sub-Saharan Africa: A Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13533.
×

(via periodic health facility surveys or routine health statistics). Information sources for these important measures remain undeveloped. Research is needed to determine a simple methodology that district health managers can apply to understand the annual reach and coverage of their services. Innovative combinations of epidemiological and demographic information would help provide annual estimates at the district level.

Health status in low-income countries is changing more rapidly now than at in any prior time in human history. To track and, eventually, to steer these population health dynamics and to understand what such transitions imply for health systems and policies will require radical changes in and a strengthening of national health-information systems so as to provide essential information. In their summary of the issues, Byass, de Savigny, and Lopez (2011) suggested that strengthening the information systems will require concerted investments on three fronts:

1.  Interim investments in sentinel or sample registration systems that provide timely and high-quality longitudinal data on deaths and causes of deaths, combined with a concurrent development of effective civil registration systems for vital statistics;

2.  Periodic national cross-sectional omnibus sample surveys of the top 10 major risk factors for the major causes of death; and

3.  Annual sub-national sample surveys or routine statistics on effective coverage of the essential health interventions relevant to these causes of death.

The workshop highlighted the need for countries in sub-Saharan Africa and their international funding partners to prioritize these three dimensions of their national strategies for strengthening health systems.

Suggested Citation:"9 Future Research Directions." National Research Council. 2012. The Continuing Epidemiological Transition in Sub-Saharan Africa: A Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13533.
×
Page 19
Suggested Citation:"9 Future Research Directions." National Research Council. 2012. The Continuing Epidemiological Transition in Sub-Saharan Africa: A Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13533.
×
Page 20
Suggested Citation:"9 Future Research Directions." National Research Council. 2012. The Continuing Epidemiological Transition in Sub-Saharan Africa: A Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13533.
×
Page 21
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Among the poorest and least developed regions in the world, sub-Saharan Africa has long faced a heavy burden of disease, with malaria, tuberculosis, and, more recently, HIV being among the most prominent contributors to that burden. Yet in most parts of Africa-and especially in those areas with the greatest health care needs-the data available to health planners to better understand and address these problems are extremely limited. The vast majority of Africans are born and will die without being recorded in any document or spearing in official statistics. With few exceptions, African countries have no civil registration systems in place and hence are unable to continuously generate vital statistics or to provide systematic information on patterns of cause of death, relying instead on periodic household-level surveys or intense and continuous monitoring of small demographic surveillance sites to provide a partial epidemiological and demographic profile of the population.

In 1991 the Committee on Population of the National Academy of Sciences organized a workshop on the epidemiological transition in developing countries. The workshop brought together medical experts, epidemiologists, demographers, and other social scientists involved in research on the epidemiological transition in developing countries to discuss the nature of the ongoing transition, identify the most important contributors to the overall burden of disease, and discuss how such information could be used to assist policy makers in those countries to establish priorities with respect to the prevention and management of the main causes of ill health.

This report summarizes the presentations and discussions from a workshop convened in October 2011 that featured invited speakers on the topic of epidemiological transition in sub-Saharan Africa. The workshop was organized by a National Research Council panel of experts in various aspects of the study of epidemiological transition and of sub-Saharan data sources. The Continuing Epidemiological Transition in Sub-Saharan Africa serves as a factual summary of what occurred at the workshop in October 2011.

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