INDEX
A
Abdominal enlargement, 260
hemopoietic system infections, 219
multiple system infections, 238
Abortions and stillbirths. 178, 260
Abscesses, 45, 49, 176, 178, 189, 260, 266
face, orbits, and tail, 183-184
Age factors
digestive diseases, 85, 86, 93, 96, 99, 105, 107, 112-113, 117, 148 , 158
hemopoietic system infections, 201, 209, 213
multiple system infections, 238-239, 249
respiratory infections, 48, 83, 102
Agents (characterization)
central nervous system infections, 223. 227
definition of term, 32
digestive system infections, 86, 87, 91, 94-95, 98, 103-104, 112, 116-117, 119-120, 123-124, 127-128, 132-133, 139-140, 142, 146, 151 , 156-157, 159, 160, 162
genitourinary system infections. 232, 234
hemopoietic system infections. 199-200, 206, 212, 215, 218
multiple systems infections, 237, 241, 244, 248, 252-253
respiratory system infections, 36, 43-44. 48-49. 51-52, 54-55. 59, 62, 65-66, 70. 72, 73. 75. 77-78, 80. 81-82
skin and joint infections, 166-167, 172, 174-175, 177, 182-183, 186 , 188. 190, 192
see also Bacterial infections (agent characterization);
Viral agents;
Zoonotic agents
Airflow systems, general, 19-20
Alopecia, see Dermatitis and alopecia
Amputations, 164, 169, 172, 178, 197. 260
Anemia, 178. 211, 212, 213, 214, 263, 266
Arthritis, 11, 45. 47. 56. 94, 158, 164, 165, 173-176, 178, 266
Ascites, 123, 201. 211. 228, 247. 267
Aspicularis tetraptera, 159-160
Athymic (nu/nu) mice, immune response, 260-261
B
Bacillus piliformis, 12, 86, 126-131
Bacterial infections (agent characterization)
arthritis, 165
digestive system infections, 126, 127-128, 131-132, 139-140, 142
genitourinary system infections, 232, 234
hemopoietic system infections, 212, 215
prevalence, general, 10, 11-12
respiratory. 43-44. 48-49, 51, 55, 62, 70, 72, 73, 75, 77-78, 80
skin and joint infections, 174-175, 177, 181, 182-183, 188
tests for. 22-24
see also specific agents
Barbering, 196
Barrier techniques, 5, 6, 14-15, 17-20
central nervous system infections, 223, 226
digestive system infections. 109, 126, 138, 146, 150, 153
multiple system infections, 240, 246, 251
respiratory infections, 41, 47, 54, 61, 79, 81
skin and joint infections, 178-179
Behavioral trauma. 182, 195-197, 207
chattering (mice), 37, 44, 70, 261
circling and rolling, 143, 224, 261
reluctance to move, 44, 49, 70. 129, 134, 149, 201, 264
self-mutilation, 184, 185, 195
Birth weight reduced, 38, 134, 261
Bordetella bronchiseptica, 35
Brain, 78, 106, 107, 202, 228, 229, 238, 239, 246, 250, 267
digestive system infections, 97, 99, 101
multiple system infections, 240
respiratory infections, 47
see also Cesarean derivation
Bronchiectasis and bronchiolectasis, 42, 45, 49, 267
C
Cages, general, 20
Carcinogenesis/spontaneous neoplasia
hemopoietic system infections, 79. 171, 205-206, 217-221
leukemia, 79, 171, 205, 217-221, 240, 243, 245, 246, 247, 270
mammary glands, 192-195
multiple systems infections. 242, 247, 250
respiratory system, 47
salivary glands, 249
skin and joint infections, 192
Cell/tissue cultures, 22. 24, 276
central nervous system infections, 227
digestive system infections. 93, 101. 107, 122, 123, 137
genitourinary system infections, 232
hemopoietic system infections, 204. 206, 210-211
multiple system infections. 238, 244, 248, 250
prevalence data and, 11-12
respiratory infections, 40, 46, 48, 53, 57, 64, 71, 74, 79, 81, 82
skin and joint infections, 176, 183. 187, 203-204
Central nervous system infections. 222-230
epizootiology, 223-224, 227-228
research history/prevalence, 222-223, 226-227, 237, 241
research interference, 226, 229-230
see also Brain;
specific agents
Cesarean derivation
central nervous system infections, 226
digestive system infections, 92, 102, 109, 115, 126, 128, 129, 131 , 138, 144, 146, 150, 153
genitourinary system infections, 233
hemopoietic system infections, 204, 213, 216
multiple systems infections, 246, 251
respiratory infections, 46, 50, 54, 58, 61, 69, 77, 79, 81, 83
skin and joint infections, 170, 175, 177, 178, 181, 186, 187, 190
Cilia-associated respiratory bacillus (CAR), 34. 38, 48-50
Circling and rolling, 143, 224, 261
Citrobacter freundii. 86, 139-141
Clinical signs, 259-265
central nervous system infections, 224, 228
definition of term, 32
digestive system infections, 88, 92, 95, 99-100, 105, 113. 117, 121 , 125, 129, 134, 140, 143, 149, 152, 155, 157, 160, 161, 163
genitourinary system infections, 189, 233, 234
hemopoietic system infections, 201-202, 207, 212, 215, 219
multiple systems infections. 238, 242, 245, 249, 254-255
respiratory system infections, 37-38, 44, 49, 52, 56, 60, 63, 66, 70, 72, 74, 76, 78, 80, 82, 172, 189
skin and joint infections, 168, 172-173, 175, 178, 180, 183-184, 186, 188, 193
Colon and cecum, 107, 129, 130, 139, 140-141, 157, 158, 159, 161, 162, 163, 249, 267
Complement fixation (CF)
central nervous system infections, 229
digestive system infections, 88, 89, 95, 96, 100, 108, 122, 126, 128
multiple system infections, 241, 243, 246
Conjunctivitis, 78, 80, 97, 99, 134, 178, 189, 261
Control techniques
central nervous system infections, 225-226, 229
definition of term, 32
digestive system infections, 90, 93-94, 97, 101-102, 103, 106, 115-116 , 118, 122
genitourinary system infections, 233, 235
hemopoietic system infections, 204, 209-210, 213, 216, 221
multiple systems infections, 240, 243, 246, 251-252, 256
respiratory system infections, 40-41, 46-47, 50, 54, 58, 61, 64, 69, 71, 72, 75, 77, 79, 81, 83
skin and joint infections, 170-171, 173, 176, 178-179, 181, 185, 187, 190, 191, 194
see also Barrier techniques;
Cesarean derivation;
Monitoring and monitored animals;
Vaccination
Conventional animal, defined, 9
Corynebacterium kutscheri.11-12. 34, 35. 54-58, 164, 178
Cyanosis, 66, 70, 178, 238, 261
Cytomegalovirus, 87-94
D
Dacryoadenitis, 189
Deaths, high and low mortality, 261-262
central nervous system infections, 224
digestive system infections, 105, 131. 140, 143
hemopoietic system infections, 201
skin and joint infections, 168, 172, 178, 179
Definitional issues, see Terminology
Dehydration, see Diarrhea
Demyelination and remyelination, 223, 225, 250, 267
Dermatitis and alopecia, 164. 262
infectious agents, 180, 181, 182, 183, 186, 191
noninfectious causes, 195-197
Dermatophytes, 185-187
Diagnosis, 259-274
central nervous system infections, 225, 229
definition of term, 32
differential diagnosis, 195-197
digestive system infections, 89-90, 93, 96, 101, 106, 115, 117-118, 122, 126, 130-131, 137, 141, 144, 150, 153. 155, 158, 160, 161, 163
genitourinary system infections, 233, 235
hemopoietic system infections, 203-204, 209, 213, 216, 220-221
laboratories for, 27
multiple systems infections, 239, 242-243, 246, 250, 255-256
respiratory system infections, 40, 46. 50, 53-54, 57-58, 61, 64, 67-68, 71, 72. 74, 77, 79, 81, 83
skin and joint infections, 164, 169-170, 173, 175, 181, 185, 187, 188-189, 191, 194, 195-197
see also Cell/tissue cultures:
Clinical signs;
Pathology;
Serologic tests;
Stain techniques
Diarrhea, 20,
digestive system infections, 102, 105. 111-118, 121, 129, 134, 140 , 149
hemopoietic system infections, 202, 262
skin and joint infections, 178
Differential diagnosis, skin infections, 195-197
Digestive system infections, 85-163
agents. 87, 91, 94-95, 98, 103-104, 11, 116-117, 119-120, 123-124, 127-128, 132-133, 139-140, 142, 146, 151, 156-157, 159. 160, 162
clinical signs, 88, 92, 95, 99-100, 105, 113, 117, 121, 125, 129, 134, 140, 143, 149, 152, 155, 157, 160, 161, 163
control, 75, 90, 93-94, 97, 101-102, 106, 115-116, 118, 122, 126, 131, 137-138, 141, 144-145, 150, 153, 156. 159. 161, 163
diagnosis, 89-90, 93, 96, 101, 106, 115, 117-118, 122, 126, 130-131, 137, 141, 144, 150, 153, 155, 158, 160, 161, 163
epizootiology, 88, 91-92, 95, 99, 104, 112-113, 117, 120-121, 124-125, 128-129, 133-134, 140, 142-143, 149, 152, 155, 157, 159, 161, 163
historic perspectives, 87, 91, 94, 97-98, 102-103, 111-112, 116, 118-119, 123-124, 127, 132, 139, 141-142
hosts, 87-88, 91, 95, 98-99, 104, 107-108, 112, 120, 124, 133, 142 , 149, 152, 155, 157, 159, 161, 162
pathology. 88-89, 92-93, 95-96, 100-101, 105-106, 113-114, 117, 121-122 , 125, 129-130, 134-137, 140-141, 143-144, 149-150, 152-153, 155, 158, 160, 161, 163
research interference, 90-91, 94, 97, 102, 109-111, 116, 118, 122-123, 126, 131, 138-139. 141, 145, 150-151, 153-154, 156, 158, 160, 161, 163
see also specific agents and organs
DNA viruses (agent characterization)
digestive system infections, 87, 91, 94-95, 123-124
multiple system infections, 237, 241, 244. 248
respiratory infections, 81
skin and joint infections, 166-167
see also specific agents
Dwarf tapeworm, 154-156
Dyspnea, 44. 52, 56. 66, 70, 212, 219, 262
E
Ear pathologies, 53, 63, 76, 143, 189. 195, 267-268
Ectromelia virus, 164, 165-171
Ectoparasites, 179-195
Encephalitis, 102, 107, 224-225, 239, 268
Encephalitozoon cuniculi.222, 226-230
Encephalomyelitis, 102, 209, 222-225, 228, 250
Endoparasites, 144-163
Enzyme-linked immunosorbent assay (ELISA), 22, 23
central nervous system infections, 229
digestive system infections, 88, 89-90, 93, 95, 96, 97, 101, 103, 108, 115, 122, 130
hemopoietic system infections, 203
multiple system infections, 242, 246, 250
respiratory infections, 40, 43, 46, 47, 50, 54, 57, 61, 81
skin and joint infections, 166, 169-170, 175
Eosinophilic crystals in lung, 39, 268
Eperythrozoon coccoides.198, 214-217
Epizootiology
central nervous system infections, 223-224, 227-228
definition of term, 32
digestive system infections, 88, 91-92, 95, 99, 104, 112-113, 117, 120-121, 124-125, 128-129, 133-134, 140, 142-143, 149, 152, 155, 157, 159, 161, 163
genitourinary system infections, 232-233, 234
hemopoietic system infections, 200-201, 207, 212, 215, 219
multiple systems infections, 237-238, 242, 245, 248-249, 254
prevalence data, general, 7-12
respiratory system infections, 37-38, 44, 49, 52, 55-56, 59-60, 62-63 , 66, 70, 73, 76, 78, 82, 248, 254
skin and joint infections, 167-168, 172, 177, 180, 186, 188, 191, 193
Escherichia coli, 126
Eye pathologies, 44, 49, 97, 100, 102, 189
see also Conjunctivitis;
Lacrymal glands
F
Facial abscesses, 183-184
G
Genitourinary system infections, 231-235
epizootiology, 44, 232-233, 234
research history/prevalence, 231-232, 234
research interference, 234, 235
see also specific agents and organs
Germfree animal, defined, 6
see also Pathogen-free animal
Giardia muris, 12, 86, 151-154
Glomerulonephritis, 56, 202, 209, 268
Gnotobiotic animal and methods, defined, 6, 9
Growth retardation, 37, 102, 117, 262
H
Haemobartonella muris, 198, 211-214
Hair
digestive system infections, 149, 152, 157
respiratory infections, 66
skin conditions, noninfectious, 196, 197
Hantaviruses, 251-256
Harderian glands, 101
Hemagglutination inhibition test (HAI), 45, 61, 83, 120, 122, 170, 173, 225, 241, 243, 246
Hemopoietic system infections, 198-221
agents, 199-200, 206, 212, 215, 218
clinical signs, 201-202, 207, 212, 215, 219
control, 204, 209-210, 213, 216, 221
diagnosis, 203-204, 209, 213, 216, 220-221
epizootiology, 200-201, 207, 212, 215, 219
hosts, 200, 206, 212, 215, 218
leukemia, 79, 171, 205, 217-221, 240, 243, 245, 246, 247
pathology, 202-203, 207-209, 212-213, 215-216, 219-220
research history/prevalence, 199. 205-206, 211, 214, 217
research interference, 204-205, 210-211, 213-214, 216-217, 221
see also specific agents and organs
Hemoglobinuria, 178, 212, 213. 263
Hemorrhages. 268
multiple system infections, 239, 254-255
skin and joint infections, 173. 193
Hepatic system, see Liver
Hepatitis virus, 20, 84, 86, 98. 102-111, 112
Historical perspectives/disease prevalence, 7-8, 9-10
central nervous system infections, 222-223, 226-227, 237, 241
definition of term, 32
digestive system infections, 87, 91, 94, 97-98, 102-103, 111-112, 116, 118-119, 123-124, 127. 132, 139, 141-142
genitourinary system infections, 231-232, 234
hemopoietic system infections, 199, 205-206, 211, 214, 217
multiple systems infections, 236-237, 241, 243, 247, 252
respiratory system infections, 35-36, 42-43, 48, 51, 54-55, 59, 62 , 65, 69, 72, 73, 75, 77, 80, 81, 97-98, 187-188
skin and joint infections, 166, 171-172, 173-174, 177, 179-180, 182 , 185, 187-188, 190, 192
Hosts
central nervous system infections, 223, 227
definition of term, 32
digestive system infections, 87-88, 91, 95, 98-99, 104, 107-108, 112, 120, 124, 133. 142, 149, 152, 155, 157, 159, 161, 162
genitourinary system, 232, 234
hematopoietic system infections, 200, 206, 212, 215, 218
multiple systems infections, 237, 241. 245, 248, 253-254
respiratory system infections, 36-37, 44. 49, 52, 55, 59, 62, 66, 70, 72, 73, 75, 78, 82
skin and joint infections, 167, 172, 175, 177, 180, 183, 186, 188, 191, 193
see also Zoonotic agents;
Transplants, tissues and organs
Hunched posture, see Reluctance to move
Hymenolepis nana.154-156
Hypersensitivity. cutaneous. 181, 184, 269
I
Immune response, 275
athymic (nu/nu) mice, immune response, 260-261
central nervous system infections, 228, 229, 230
digestive system infections, 89, 96, 107-108, 109-110, 114, 125, 130, 135, 137, 143, 144, 151, 153, 154, 158
glomerulonephritis, 56, 202, 209
hemopoietic system infections, 198, 202, 203, 208-209, 210, 211, 212, 216-217
multiple system infections, 240, 243, 247, 249
respiratory infections, 35, 39, 41-42, 45-46, 50, 58, 64, 66, 67, 68, 69
skin and joint infections. 171, 176, 180, 185, 194
see also Serologic tests
Inapparent infections, see Subclinical infections
Inclusions, 269
intracytoplasmic, skin, 169, 191
intracytoplasmic and intranuclear, 250
intranuclear, 83, 88, 92, 96, 125
Indirect immunofluorescent antibody test (IFA), 22, 23
central nervous system infections, 229
digestive system infections, 88, 89, 95, 96, 101, 115, 117-118, 128 , 130
hemopoietic system infections, 200, 203, 216, 204, 221
multiple system infections, 242-243, 246
respiratory infections, 40, 50, 68, 71
skin and joint infections, 170
Interference with research, see Research complications
Intestines, small, 269
blunting of villi, 107, 114, 117, 125
enteritis, 107, 117, 121, 125, 129, 130, 150, 152-153, 154-155
helminth parasite, 156
protozoan parasites, 146, 149-151, 152-153
syncytial epithelial giant cells, 107, 117
J
Jaundice. 105, 121, 238, 239, 263
Joints, see Skin and joint infections
K
Keratitis, 100
Kidneys
digestive system infections, 91, 92, 98, 121, 122, 126
genitourinary system infections, 228, 229, 233
multiple systems infections, 244, 248. 249. 250. 254
respiratory infections. 56, 74
Kilham rat virus, 10, 58, 236-240, 241. 242, 246
Klebsiella pneumoniae, 35, 72-75
L
Lacrymal glands, 92, 93, 97, 99, 100, 102
Lactic dehydrogenase-elevating virus, 198, 205-211, 216
Leptospira interrogans serovar ballum.231-234
Leukemia. 79. 171, 205, 217-221, 240, 243, 245, 246, 247, 270
Life cycles, parasites
digestive system, 146, 152, 154-155, 157, 159, 160-161, 162
skin and joints, 180
Listeria monocytogenes.211
Litter size reduced, 37, 134, 263
central nervous system infections, 226
digestive system infections, 86, 98, 102-111, 112, 121, 129, 135, 136, 138
hemopoietic system infections, 202-203, 207, 216
hepatitis, 20, 53, 84, 86, 98, 102-111, 112, 268-269
jaundice, 105, 121, 238, 239, 263
multiple system infections, 238, 239, 243, 249
Lung pathology. 10, 35, 39, 45, 49, 52, 73, 83, 173, 249, 254, 255
Lymphadenopathy. 74, 76, 129, 178, 181, 219, 263, 270
digestive system infections, 95, 96, 100, 136
hemopoietic system infections, 207, 208, 219
respiratory infections, 63, 74, 76
skin and joint infections, 169, 178, 181, 189
Lymphocytic choriomeningitis virus, 10, 198, 199-205, 216
M
Mammary tumor virus, 192-195
Mediastinitis, 53
Minute virus of mice, 243-247
Monitoring and monitored animals, 9, 13, 14, 15, 18, 21-27
digestive system infections, 97, 100
skin and joint infections, 179
Mouse cytomegalovirus, 87-91, 145
Mouse hepatitis virus, 84, 102-111
Mouse mammary tumor virus, 192-195
Mouse minute virus, 243-247
Mouse papule virus, 190-191
Mouse rotavirus, 20, 86, 111-116
Mouse thymic virus, 94-97
Mousepox virus, 164-171
Multiple systems infections, 236-256
agents, 237, 241, 244, 248, 252-253
clinical signs, 173, 238, 242, 245, 249, 254-255
control, 240, 243, 246, 251-252, 256
diagnosis, 239, 242-243, 246, 250, 255-256
epizootiology, 237-238, 242, 245, 248-249, 254
hosts, 237, 241, 245, 248, 253-254
pathology, 238-239, 242, 245-246, 249-250, 255
research history/prevalence, 236-237, 241, 243, 247, 252
research interference, 240, 243, 246-247, 252, 256
Murine respiratory mycoplasmosis (MRM), 44-45, 46. 47. 48, 49, 50
Mycobacterium avium-intracellulare.62-64
Mycoplasma arthritidis.11, 164. 173-176
Mycoplasma neurolyticum.35, 77-79
Mycoplasma pulmonis, 33-34, 36, 38, 40, 42-48, 50, 174, 188, 231
Myobia musculi, 179-182
Myocoptes musculinus.182
N
Necropsy
digestive system infections, 108, 117, 130, 158
respiratory infections, 53, 68, 74
Neoplasia, 271
leukemia, 79, 171, 205, 217-221, 240, 243, 245, 246, 247. 270
mammary glands, 192-195
salivary glands, 249
see also Carcinogenesis/spontaneous neoplasia
O
Otitis media, 143, 195, 189, 267
P
Pallor, see Anemia
Papule virus, 190-191
Paralysis, 178, 207, 209, 224, 249, 250, 263-264
Parasitic infections, 45
digestive system, 127, 145-163
ectoparasites, 179-195
endoparasites. 144-163
genitourinary system, 226-230
multiple systems, 250
prevalence data, 12
skin and joints, 179-185
testing for, 24
see also Life cycles, parasites;
Protozoa
Pasteurella pneumotropica.11, 35, 187-190
Pathogen-free animal, 6, 9, 13-16
see also Specific pathogen-free animal
Pathology, 266-274
central nervous system infections, 224-225, 228-229
definition of term, 32
digestive system infections, 88-89, 92-93, 95-96, 100-101, 105-106, 113-114, 117, 121-122, 125, 129-130, 134-137, 140-141, 143-144, 149-150 , 152-153, 155, 158, 160, 161, 163
genitourinary system infections, 233, 235
hemopoietic system infections, 202-203. 207-209, 212-213, 215-216, 219-220
multiple systems infections, 238-239, 242, 245-246, 249-250, 255
respiratory system infections, 38-40, 44-45, 49-50, 52-53, 56-57, 60-61, 63, 66-68, 71, 72, 74, 76, 78-79, 81, 82-83, 105, 106, 107, 121, 173, 255
skin and joint infections, 168-169, 173, 175, 178, 180-181, 184-185, 186, 188, 191, 193-194
see also Clinical signs;
specific organs and systems
Pleural effusion, 39, 173, 271
Pneumocystis carinii, 35, 64-69
Pneumonia, 10, 76, 173, 271-272
embolic, 56
interstitial, 38, 60, 71, 83. 100, 106-107
Pneumonia virus of mice. 35, 50, 59-62, 82
Polioencephalomyelitis, see Encephalomyelitis
Polyoma virus. 19, 81, 205, 247-251
Polyplax serrata, 215
Poxviruses, 164-171, 171-173, 178
Preputial gland abscesses, 184
Protozoa
central nervous system infections, 227
digestive system infections, 146, 149-153, 160, 162
respiratory infections, 65
serologic tests, 22
Pseudomonas aeruginosa, 11, 141-145
Pseudotuberculosis, 57
R
Radfordia affinis.182
Rat coronavirus, 58
Rat cytomegalovirus, 91-94
Rat rotavirus, 116-118
Rectal prolapse, 139, 140, 157, 264
Reluctance to move, 44, 49, 70, 129, 134, 149, 201, 264
Research, see Historical perspectives/disease prevalence
Research complications, 3, 275-276
central nervous system infections, 226, 229-230
definition of term, 32
digestive system infections. 90-91, 94, 97, 102, 109-111, 116, 118 , 122-123, 126, 131, 138-139, 141, 145, 150-151, 153-154, 156, 158 , 160, 161, 163
genitourinary system infections, 234, 235
hemopoietic system infections, 204-205, 210-211, 213-214, 216-217, 221
multiple systems infections, 240, 243, 246-247, 252, 256
respiratory system infections, 41-42, 47-48, 50. 54, 58, 61-62, 64 , 69, 72, 75, 77, 79, 81, 84, 102, 123
significance, general definition, 31
skin and joint infections, 171, 173, 176, 179, 181-182, 185, 187. 190, 191, 194-195
Respiratory system infections, 33-84, 231
agents, 34, 36, 43-44, 48-49, 51-52, 54-55, 59, 62, 65-66, 70, 72, 73, 75, 77-78, 80, 81-82
airflow barrier systems. 19-20
clinical signs, 37-38, 44, 49, 52, 56, 60, 63, 66, 70, 72, 74, 76, 78, 80, 82, 172, 189
control techniques, 40-41. 46-47, 50, 54, 58, 61, 64, 69, 71, 72, 75, 77, 79, 81, 83
diagnosis. 40, 46, 50, 53-54, 57-58, 61, 64, 67-68, 71, 72, 74, 77 , 79, 81, 83
epizootiology. 37-38, 44, 49, 52, 55-56, 59-60, 62-63, 66, 70, 73, 76, 78, 82, 248, 254
hosts, 36-37, 44, 49, 52, 55, 59, 62, 66, 70, 72, 73, 75, 78, 82
pathology, 38-40, 44-45, 49-50, 52-53, 56-57, 60-61, 63, 66-68, 71 , 72, 74, 76, 78-79, 81, 82-83, 105, 106, 107, 121, 173, 255
research history/prevalence, 33, 35-36, 42-43, 48, 51, 54-55, 59, 62, 65, 69, 72, 73, 75, 77. 80, 81, 97-98, 103, 187-188
research interference, 41-42, 47-48, 50, 54, 58, 61-62, 64, 69, 72 , 75, 77, 79, 81, 84, 102, 123
see also specific agents and organs
RNA viruses (agent characterization)
central nervous system infections, 223
digestive system infections, 86, 98, 103-104, 112, 116, 119-120
hemopoietic system infections, 199-200, 206, 218
multiple systems infections. 252-253
respiratory infections, 36, 59, 84, 98
skin and joint infections, 192
see also specific agents
Rolling, see Circling and rolling
Runting, see Wasting syndrome
S
Salivary glands and saliva, 87, 88, 91-92, 95, 96, 99, 100, 101, 102, 249, 272
Salmonella enteritidis,11, 86, 132-139, 169, 178
Salpingitis, 45
Sampling, 25-26
Scrotal cyanosis, 238
Scrotal hemorrhage, 239
SDA/RCV, 10
Self-mutilation, 184, 185, 195
Sendai virus, 10, 34, 35-41, 50, 58
Sentinel animals, 27
Septicemia, 272
digestive system infections, 136, 143, 144, 145
genitourinary system infections, 233
respiratory infections, 54, 56-57
skin and joint infections, 178, 203
Serologic tests, 22-24
central nervous system infections, 225-226, 227, 229
digestive system infections. 101, 103, 117-118, 124, 128, 133
genitourinary system infections, 232, 233
multiple system infections, 237, 239-243, 246, 255
respiratory infections, 43, 54, 61, 68, 74, 75
skin and joint infections. 169, 175
see also Enzyme-linked immunosorbent assay;
Hemagglutination inhibition test;
Indirect immunofluorescent antibody test
Sialodacryoadenitis virus, 35, 43, 45, 58, 97-102, 189
Silver stain, see Stain techniques
Skin and joint infections. 164-197
agents, 166-167, 172, 174-175, 177, 182-183, 186, 188, 190, 192
clinical signs. 168, 172-173, 175, 178, 180, 183-184, 186, 188, 193
control, 170-171, 173, 176, 178-179, 181, 185, 187, 190, 191, 194
diagnosis, 164, 169-170, 173, 175, 181, 185, 187, 188-189, 191, 194
epizootiology, 167-168, 172, 177, 180, 186, 188, 191, 193
hosts, 167, 172, 175, 177, 180, 183, 186, 188, 191, 193
pathology, 168-169, 173, 175, 178, 180-181, 184-185, 186, 188, 191 , 193-194
parasites, 179-182
research history/prevalence. 166, 171-172, 173-174, 177, 179-180, 182, 185, 187-188, 190, 192
research interference, 171. 173, 176, 179, 181-182, 185, 187, 190, 191, 194-195
see also Dermatitis and alopecia;
specific agents
Skin conditions, noninfectious, 195-197
Skin ulceration, 180, 183, 186, 264
Social behavior, see Behavioral trauma
Specific pathogen-free animal, 6, 9
central nervous system infections, 226
digestive system infections, 153
hemopoietic system infections, 204, 216
multiple system infections, 240, 246, 255
skin and joint infections. 176
Spironucleus muris, 12, 86, 146, 149-151
central nervous system infections, 226, 230
respiratory system infections, 41, 51, 63
skin and joint infections, 169, 171, 178
Stain techniques
digestive system infections, 130, 150, 161, 163
hemopoietic system infections, 213, 216, 218
respiratory infections, 50, 68
Staphylococcus aureus.123, 164-165, 182-185
Streptobacillus moniliformis, 164, 169, 176-179
Streptococcus pneumoniae, 34, 51-54
Streptococcus pyogenes, 35, 75-77
Subclinical infections, 263, 276
central nervous system infections, 224
digestive system, 87, 88, 92, 95, 97, 99-100, 105, 111, 128, 129, 131, 132, 134, 149, 151, 152, 157, 160, 161
genitourinary system infections, 233
hemopoietic system infections. 201, 207, 210, 212, 214
multiple system infections, 238, 240, 242, 245
respiratory, 33, 37, 44, 46, 47, 54, 55, 57, 60, 66, 69, 70, 72, 78, 80, 82, 174
skin and joints, 11, 168, 172, 174, 175, 176, 178, 180
Surveillance, see Monitoring and monitored animals
Swelling (endema), 99, 169, 178, 197, 264
Symptoms, see Clinical signs;
specific symptoms
Syphacia obvelatalmuris, 20, 156-158
Synctal giant cells. 38, 45, 107, 117, 273
T
Terminology
agent characterization, 31-32
infection vs disease, 3-4
microbial and pathogen terms, 4-9, 13
Theiler's virus, 10-11, 222-226
Thymus, 94-97, 100, 207, 208, 220, 273
Tissue cultures, see Cell/tissue cultures
Toolan H-1 virus, 10
Transplants, tissue and organs, 276
central nervous system infections, 228, 230
digestive system infections, 86, 90, 94, 104, 107, 121, 122-123, 131, 138
hemopoietic system infections, 198, 199, 200, 203-211, 213, 214
multiple system infections, 238, 240, 243, 245, 246, 249, 250, 251 , 255-256
respiratory infections, 41, 42, 84, 84
skin and joint infections, 176
Transportation of animals, general, 13-14
Tritrichomonas muris.12, 162-163
Tumors, 276
central nervous system infections, 228, 230
digestive system infections, 86, 90, 94, 104, 107, 121, 122-123, 131, 138
hemopoietic system infections, 198, 199, 200, 203-211, 213, 214
multiple system infections, 238, 240, 243, 245, 246, 249, 250, 251 , 255-256
respiratory infections, 41, 42, 48, 84
skin and joint infections, 176, 192-195, 199
see also Neoplasia
Tyzzer's disease, 127-131
U
Uterine pathologies, 45, 239, 274
V
Vaccination
digestive system infections, 116, 144-145
respiratory infections, 41, 54
skin and joint infections, 170-171
Viral agents
prevalence, general, 7-8, 9-10
respiratory, 54
skin and joint infections, 190
tests for, 22-24
see also DNA viruses (agent characterization);
Poxviruses;
RNA viruses (agent characterization);
specific agents
W
Wasting syndrome, 105, 238, 246, 249, 265
see also Anorexia:
Weight loss
Weaning behavior, 195-196
Weight loss
birth weight reduced, 38, 134, 261
digestive system infections, 102, 105, 116, 134, 140, 149, 151, 152 , 155
emaciation, 262
respiratory infections, 44, 52, 56, 66, 67, 70
skin and joint infections, 178
West Germany, 12
Whisker-trimming, 196
Wounds, 195-196
X
X-irradiation, 92, 131, 152, 154, 171, 205, 209, 214
Z
Zoonotic agents. 276
central nervous system infections, 229
digestive system infections, 116, 118, 133, 138, 154, 156
genitourinary infections, 230, 232, 233, 234
hemopoietic system infections. 199, 200, 201-202, 204, 205
multiple system infections, 251-256
respiratory infections. 52
