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Appendix B
Workshop Agenda
Improving the Translation of Research Findings into Clinical Practice:
I. The Potential and Problems of Modern Methods of Clinical
Investigation
Wednesday, May 3, 1989
8:00 a.m.
8:30 a.m.
Session One:
Registration and Continental Breakfast
Welcome and Opening Remarks
Samuel Thier, President, Institute of Medicine
Gerald Laubach, Chair, Committee on Technological
Innovation in Medicine
Setting the Stage
Keynote Address
8:45 a.m.
Technological Innovation and Evaluation in Medicine
Samuel Thier, Institute of Medicine
Session Two: Outcomes and Evaluative Research
Moderator: Paul Parkman, Food and Drug
Administration
202
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APPENDIX B
9:15 a.m. The Selection of Endpoints in Evaluative Research
John Bunker, Stanford University
9:45 a.m.
203
Advances in Health Status Measurement: The Potential
to Improve Experimental and Non-Experimental Data
Collection
Marilyn Bergner, Johns Hopkins University
10:15 a.m. General Discussion
10:45 a.m. Break
Session Three: Modern Epidemiologic Methods for Obtaining
Primary Evidence
Moderator: Paul Stolley, University of Pennsylvania
11:00 a.m. What Is Outcomes Research?
John Wennberg, Dartmouth College
11:45 a.m.
Strengths and Weaknesses of Health Insurance Data
Systems for Assessing Outcomes
Leslie Roos and Noralou Roos, University of Manitoba,
Canada
12:15 p.m. General Discussion
1:00 p.m.
2:00 p.m.
Lunch
Prescription-Event Monitoring: An Example of Total
Population Post-Marketing Drug Surveillance
William Unman, Drug Safety Research Unit,
United Kingdom
Discussant: Brian Strom, University of Pennsylvania
2:30 p.m. General Discussion
Session Four: Modern Methods to Synthesize Existing Evidence
Moderator: Frederick Mosteller, Harvard University
3:00 p.m. The Value of Modern Methods of Decision Analysis
Albert Mulley, Massachusetts General Hospital
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204
3:30 p.m.
4:00 p.m.
4:30 p.m.
5:30 p.m.
6:15 p.m.
Thursday, May 4, 1989
APPENDIX B
The Value of Modern Methods of Meta-Analysis
Stephen Thacker, Center for Environmental Health and
Injury Control, Centers for Disease Control
A Bayesian Approach to Clinical Evaluation
David Eddy, Duke University
General Discussion
Adjourn and Reception
Dinner
8:30 a.m. Continental Breakfast
Session Five: Modern Methods of Clinical Evaluation: What Are
the Challenges and Consequences for Technological
Innovation in Medicine?
Keynote Address
9:15 a.m.
Can We Improve the Transfer of Research Findings Into
Clinical Practice Through Modern Methods of
Evaluation?
David Eddy, Duke University
10:00 a.m.
10:15 a.m.
11:45 a.m.
12:45 p.m.
Break
Roundtable Discussion (A)
Moderator: Harvey Fineberg, Harvard University
Panel Members:
David Eddy, Duke University
Alvan Feinstein, Yale University
Robert Levy, Sandoz Research Institute
Robert Temple, Food and Drug Administration
Salim Yusuf, National Heart, Lung, and Blood Institute
Lunch
Factors That Influence the Utilization of Modern
Evaluative Methods
Kenneth Melmon, Stanford University
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APPENDIX B
1:30 p.m.
3:00 p.m.
3:15 p.m.
205
Roundtable Discussion (1~)
Moderator: Charles Sanders, Squibb
Panel Members:
Susan Bartlett Foote, University of California, Berkeley
Jere Goyan, University of California, San Francisco
Ben Holmes, Hewlett-Packard
William Hubbard, Council on Health Care Technology,
Institute of Medicine
Kenneth Melmon, Stanford University
Stephen Sherwin, Genentech
M. Roy Schwarz, American Medical Association
Summary of the Meeting
Gerald Laubach, Chair, Committee on Technological
Innovation in Medicine
Adjourn
Representative terms from entire chapter:
modern methods
