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B NTH Consensus Development Conferences Table B. 1 provides a list of the National Institutes of Health (NIH) consensus development conferences. TABLE B.l NTH Consensus Development Conferences Date Conference Title Cosponsora 977 September 14-16 Breast Cancer Screening NCI 1978 May 22 Educational.Needs of NCI Physicians and Public Regarding Asbestos Exposure June 13-14 Dental Implants: Benefit and NIDR Risk June 26-28 Mass Screening for Colo-Rectal NCI Cancer July 10-11 Treatable Brain Diseases in the NIA Elderly July 20 Indications for Tonsillectomy NINCDS and Adenoidectomy: Phase I September 14 Availability of Insect Sting Kits NIAID to Non-Physicians September 18-20 Mass Screening for Lung NCI Cancer 65 Table B.l continues

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66 TABLE B.1 Continued APPENDIX B Date Conference Title Cosponsora November 10-11 Supportive Therapy in Bum NIGMS Care December 4-5 Surgical Treatment of Morbid NIAMDDb Obesity 1979 February 16 Pain, Discomfort, and (HHS) Humanitarian Care March 5-7 Antenatal Diagnosis NICHD April 23-24 Transfusion Therapy in NHLBI Pregnant Sickle Cell Disease Patients April 26-27 Improving Clinical and NHLBI Consumer Use of Blood Pressure Measuring Devices June 5 The Treatment of Primary NCI Breast Cancer: Management of Local Disease June 27-29 Steroid Receptors in Breast NCI Cancer September 10-11 Intraocular Lens Implantation NEI September 13-14 Estrogen Use and NIA Postmenopausal Women October 15-16 Amantadine: Does it Have a NIAID Role in the Prevention and Treatment of Influenza? October 17-19 The Use of Microprocessor- DRS Based "Intelligent" Machines in Patient Care November 28-30 Removal of Third Molars NIDR 1980 April 10-12 Thrombolytic Therapy in NHLBI Thrombosis May 19-21 Febrile Seizures NINCDS July 14-16 Adjuvant Chemotherapy of NCI Breast Cancer July 23-25 Cervical Cancer Screening: The NCI/NIAINICHD Pap Smear August 20-22 Endoscopy in Upper GI NIAMDDb Bleeding September 22-24 Cesarean Childbirth September 29-October 1 CEA as a Cancer Marker NICHD NCI

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APPENDIX B 67 Date Conference Title Cosponsora December 3-5 Coronary Artery Bypass NHLBI Surgery: Scientific and Clinical Aspects 1981 March 2-4 November 4-6 1982 The Diagnosis and Treatment of NINCDS/NIAID/ Reye's Syndrome NIDDK/ NICHD/ NIEHSIDRR Computed Tomographic NINCDS/NCI Scanning of the Brain January 13-15 Defined Diets and Childhood NIAID/NICHD Hyperactivity March 1-3 Total Hip Joint Replacement NlADDKb November 1-3 Clinical Applications of DRS Biomaterials 1983 March 7-9 Critical Care Medicine CC June 20-23 Liver Transplantation NIADDK~ September 27-29 Treatment of NHLBI Hypertriglyceridemia October 24-26 Precursors to Malignant NCI Melanoma November 15-17 Drugs and Insomnia: The Use (NIMH) of Medications to Promote Sleep December 5-7 Dental Sealants in the NIDR Prevention of Tooth Decay 1984 February 6-8 Diagnostic Ultrasound Imaging NICHD/DRR/(FDA) in Pregnancy February 27-29 Analgesic-Associated Kidney NIADDKb Disease April 24 Osteoporosis NIADDK. April 24-26 Mood Disorders: Pharmacologic (NIMH) Prevention of Recurrences September 24-26 Fresh Frozen Plasma: NHLBI/(FDA) Indications and Risks Table B.] continues

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68 TABLE B.l Continued APPENDIX B Date Conference Title Cosponsora December 3-5 Limb-Sparing Treatment of NCI Adult Soft-Tissue and Osteosarcomas December 10-12 Lowering Blood Cholesterol to NHLBI Prevent Heart Disease 1985 January 28-30 Travelers' Diarrhea NIAID February 11-13 Health Implications of Obesity NIADDKbINHLBI April 22-24 Anesthesia and Sedation in the NIDR Dental Office June 10-12 Electroconvulsive Therapy (NIMH) September 9-11 Adjuvant Chemotherapy for NCI Breast Cancer 1986 January 13-15 Health Implications of NCI/NIDR Smokeless Tobacco Use March 24-26 Prevention of Venous NHLBI Thrombosis and Pulmonary Embolism May 19-21 Integrated Approach to the CC Management of Pain June 2-4 -- The Utility of Therapeutic NINCDS Plasmapheresis for Neurological Disorders July 7-9 Impact of Routine HTLV-III NHLBI Antibody Testing of Blood and Plasma Donors on the Health of He Public September 29-October 1 Infantile Apnea and Home NICHD Monitoring October 6-8 Platelet Transfusion Therapy NHLBI December 8-10 Diet and Exercise in NIDDKb Noninsulin- Dependent Diabetes Mellitus 1987 April 6-8 Newborn Screening for Sickle NHLBI Cell Disease and Other Hemoglobinopadties June 15-17 Management of Clinically NCI Localized Prostate Cancer

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APPENDIX B 69 Date Conference Title Cosponsora July 6-8 Differential Diagnosis of NIA Dementing Diseases July 13-15 Neurofibromatosis NINCDS October 19-21 Geriatric Assessment Methods NIA for Clinical Decision Making October 26-28 Magnetic Resonance Imaging CC 1988 March 28-30 Prevention and Treatment of MIDDY Kidney Stones May 2-4 Cochlear Implants ~ NINCDS June 13-15 Dental linplants NIDR June 27-29 Perioperative Red Cell NHLBI Transfusion October 3-5 Urinary Incontinence ~ NIA 1989 March 6-8 Therapeutic Endoscopy and NIDDKb Bleeding Ulcers April 17-19 Oral Complications of Cancer NIDR Therapies: Diagnosis, Prevention, and Treatment May 8-10 Sunlight, Ultraviolet Radiation, NIAMS and the Skin September 13-15 Treatment of Destructive NICHD Behaviors in Persons with Developmental Disabilities 1990 January 22-24 Noise and Hearing Loss NIDCD March 19-21C Surgery for Epilepsy NINDS March 26-28C Treatment of Sleep Disorders in NIAJNHLBI/ Older Persons NINDS/ (NIMH) ApriVMayC Adjuvant Therapy for NCI Colorectal Cancer April/MayC Therapeutic Uses of NIAID Gammaglobulin June 18-21C Treatment of Early-Stage Breast NCI Cancer Table B.] continues

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70 TABLE B.l Continued APPENDIX B Date Conference Title Cosponsora JulyC NovemberC DecemberC Therapeutic Uses of Botulinum NINDS Toxin Hyperparathyroidism NlDDKb Treatment of Morbid Obesity NIDDKb 1991 JanuaryC Melanoma NCI aEach conference is normally sponsored by OMAR and one or more bureau, institute, or division of NIH, which are abbreviated as follows. CC Warren Grant Magnuson Clinical Center DRR Division of Research Resources DRS Division of Research Services NCI National Cancer Institute NEI National Eye Institute NHLBI National Heart, Lung, and Blood Institute NLM National Library of Medicine NIA National Institute on Aging NIADDKb National Institute of Arthritis, Diabetes, and Digestive and Kidney Diseases (see note b) NIAID National Institute of Allergy and Infectious Diseases NIAMDDb National Institute of Arthritis, Metabolism, and Digestive Diseases (see note b) NIAMS National Institute of Arthritis and Musculoskeletal and Skin Diseases NICHD National Institute of Child Health and Human Development NIDCD National Institute on Deafness and Other Communication Disorders NIDDKb National Institute of Diabetes and Digestive and Kidney Diseases (see note b) NIDR National Institute of Dental Research NIEHS National Institute of Environmental Health Sciences NIGMS National Institute of General Medical Sciences NINCDS National Institute of Neurological and Communicative Disorders and Stroke NINI)S National Institute of Neurological Disorders and Stroke Sponsors from orga~iizations outside NIH are shown in parentheses and are abbreviated as follows: HHS NIMH Food and Drug Administration U.S. Department of Health and Human Services National Institute of Mental Health bOver time the name of the NIDDK has changed. From May 1972 to June 1981 the Institute was known as the NIAMDD, from June l9B1 to April 1986 it was the NIADDK, and from April 1986 to the present it has been the NIDDK. CThese are the consensus conferences planned for 1990.