Below are the first 10 and last 10 pages of uncorrected machine-read text (when available) of this chapter, followed by the top 30 algorithmically extracted key phrases from the chapter as a whole.
Intended to provide our own search engines and external engines with highly rich, chapter-representative searchable text on the opening pages of each chapter.
Because it is UNCORRECTED material, please consider the following text as a useful but insufficient proxy for the authoritative book pages.
Do not use for reproduction, copying, pasting, or reading; exclusively for search engines.
OCR for page 1
RODENTS
Footnote symbols are used consistently in this section, as follows:
* *.*
or indicate companies holding registered trademarks;
11
indicates timed and untimed pregnant females available;
§ and @ are used for footnotes other than those listed above.
The terms used in this section are defined in the "Terms and Defin-
itions" section and are abbreviated as follows:
Microbiological status:
C conventionally reared
BR barrier reared or
specific pathogen
free (SPF)
Rearing by means other than natural mother:
f fostered
DF defined flora
OF germfree
GN gnotobiote
fh fostered by hand
In the "Mice" section, a letter and two numbers in brackets, e.g., [J72],
following an fh subscript indicates the place and year of hysterectomy
derivation of the substrain.
Surgical modifications available:
adr adrenalectomy
cas castration
hyp hypophysectomy
nep unilateral nephrectomy thy
ova ovariectomy
used:
pan pancreatectomy
pare parathyroidectomy
thr thyroidectomy
thymectomy
In the outbred "Guinea Pigs" section, the following color codes are
A albino
1
C colored
OCR for page 2
2
RODENTS
In the "Hamsters" section, pathology and life span information has
been included in an attempt to make the listings additionally useful for
research purposes.
OUTBRED STOCK INFORMATION
BREED OR STOCK DESIGNATION: "International Standardized Nomenclature for
Outbred Stocks of Laboratory Animals," International Committee on Labora-
tory Animals (ICLA) Bulletin, No. 30, March 1972, has been used in desig-
nating these animals. Copies of this bulletin are available from the
Institute of Laboratory Animal Resources (ILAR), 2101 Constitution Avenue,
N.W., Washington, D.C. 20418.
.
Letters preceding the colon designate the supplier/breeder code
consisting of a capital and two or three lower case letters.
ˇ Capital letters following the colon are used by a breeder to
identify his stock.
ˇ Letters in parentheses denote origin of stock.
ˇ Subscript symbols (shown on previous page) indicate rearing by
means other than natural mother.
MICROBIOLOGICAL STATUS: Abbreviations have been listed previously. Ex-
planations are provided in the "Terms and Definitions" section.
COLONY CLOSED 19
the colony.
__
Year after which no new animals were introduced into
SURGICAL MODIFICATIONS AVAILABLE: Surgical modifications of animals that
can be provided by suppliers by arrangement.
listed on the previous page.
The abbreviations used are
CODE: Code designations for suppliers. Names, addresses, and phone num-
bers for suppliers are listed in the final section of the book.
INBRED STRAIN INFORMATION
STRAIN DESIGNATION: The following references have been used in designa-
ting strains of inbred mice and inbred rats, respectively:
Staats, J. 1976. Standardized nomenclature for inbred strains of
mice: Sixth listing. Cancer Res. 36:4333-4377.
Festing, M., and J. Staats. 1973. Standardized nomenclature for
inbred strains of rats. Fourth listing. Transplantation 16(3):221-245.
0 The strain designation is given in capital letters followed by
a slash.
OCR for page 3
3
RODENTS
ˇ The substrain designation follows the slash and may be given as
numbers or as individual or company codes. Numbers are used to
denote substrains that were derived from a common strain but
separated before the completion of inbreeding. The individual
or company code, written as an initial capital letter followed
by up to three lower case letters, indicates the name of the
person, laboratory, or company holding the strain. Several
codes may appear together, indicating the history of the strain
when read from left to right. The current holder's code appears
last (farthest right) in the line.
ˇ Abbreviations indicating rearing by means other than natural
mother (listed previously) may be included.
MICROBIOLOGICAL STATUS: Abbreviations have been listed previously. Ex-
planations are provided in the "Terms and Definitions" section.
PRESENT F NUMBER: Current generation of inbreeding, either since the
animals were acquired by the current supplier, or over the entire history
of the strain.
SURGICAL MODIFICATIONS AVAILABLE:
Surgical modifications of animals that
can be provided by suppliers by arrangement. The abbreviations used have
been listed previously.
CODE: Code designations for suppliers. Names, addresses, and phone num-
bers for suppliers are listed in the final section of the book.
OTHER RODENTS
Rodents other than those commonly used in the laboratory may be found in
the section, "Other Vertebrates: Mammals."
OCR for page 4
4
RODENTS
. . .
MONGOLIAN (MON) GERBILS (Meriones unguiculatus) Outbred
Microbio- Colony Surgical
Stock logical Closed Modifications
Designation Status 19-- Available Code
Anp:(MON) C __ Anp
Chi:(MON) C 64 Chi
Haf:(MON) C 67 Haf
Has:(MON) C 76 cas, ova, others Has
Hul:(MON) C __ Hul
Rbc: BROWN BEAUTY(MON) C
Rbc
Tum:(MON) C 54 Tum
Wbs:(MON)[linebred] C 71 Wbs
OCR for page 5
5
RODENTS
MONGOLIAN (MON) GERBILS (Meriones unguiculatus) Inbred
Microbio- Surgical
Strain logical Present Modifications
Designation Status F Number Available Code
MON/Has
MON/Tum
32
MONGOLIAN (MON) GERBILS (Meriones unguiculatus) Mutant
cas, ova, others Has
Tum
Microbio- Stock or Surgical
Mutant logical Strain On Which Modifications
Designation Status It Is Carried Available Code
black
spot
Has:(MON)
MON/Has
Tum:(MON)
Haf:(MON)
cas, ova, others Has
cas, ova, others Has
Tum
Haf
OCR for page 6
6
RODENTS
GU INEA P IGS (cavia porcel l us3 Outbred
Microbio- Colony Surgical
Stock logical Closed Modifications
Desi~nation Status 19-- Available Code
DUNKIN-HARTLEY ( DH )
Bil:(DH) C 72 cas, ova Bil
Cam:(DH) C 61 cas, ova Cam
Dla:(DH)f' BR 75 ova Dla
HARTLEY (HA)
Anp:(HA) C __ Anp
Cam:FCRC(HA) C 62 cas, ova Cam
Cam:(HA) C 64 cas, ova Cam
Cam: NON-RESPONDERS C 68 cas, ova Cam
TO PLL(HA)
Cam: RESPONDERS TO C 68 cas, ova Cam
PLL(HA)
Can:(HA) BR 69 Can
Clc:(HA) C __ Clc
Crc:(HA) C 62 Crc
Crl:COBS@(HA) BR, DF 70
Crl
Dsk:(HA) C __ Dsk
Elm:(HA) C 69 adr, hyp, ova, Elm
thy
Fab:(HA)'' C __ cas, ova, others Fab
Gin:(HA) C __ Gin
COBS~ is a registered trademark of The Charles River Breeding Labor-
atories, Inc., Wilmington, Massachusetts.
Timed and untimed pregnant females available.
OCR for page 7
7
RODENTS
GUINEA PIGS (Cavia porcellus) Outbred
Microbio- Colony Surgical
Stock logical Closed Modifications
Designation Status 19-- Available Code
HARTLEY (HA) - cont.
Mcr:(HA)
New:(HA)
Old:(HA)
Pep:(HA)
Roc:(HA)
Sim:(HA)
Suo:tHA)
Swf:(HA)
Wbs:(HA)[linebred]
SHORTHAIR (SR)
Akl:AK(SR)
Anp:C(SR)
Hla:(HA) BR 68 Hla
Ils:(HA) C 65 Ils
Kel:(HA) C 74 Kel
C
C
C
C
C
C
C
C
C
C
C
C
Cam:MOEN CHASE A(SR)
SHORTHAIR (SR)--AMERICAN
Chr:AME RICAN C(SR) C
Dsk:AMERICAN A(SR)
Hul:AMERICAN A(SR)
Hul:AMERICAN C(SR)
Mcr
76
71
76
71
60 cas, ova
New
Old
Pep
Roc
Sim
Suo
Swf
Wbs
Akl
Anp
Cam
Chr
Dsk
Hul
Hul
OCR for page 8
8
RODENTS
GUINEA PIGS (Cavia porcell us) Outbred
-
Microbio- Colony Surgical
Stock logical Closed Modifications
Designation Status 19-- Available Code
SHORTHAIR (SR)--AMERICAN - cont.
Isa:AMERICAN AtSR) C
Isa
Isa:AMERICAN C(SR) C __ Isa
Pad: AMERICAN C( SR) C __ Pad
Ssi:AMERICAN A(SR) C 68 Ssi
SHORTHAIR (SR)--ENGLISH
Cam: ENGLISH A(SR) C __ cas, ova Cam
Cam:ENGLISH C(SR) C -- . cas, ova Cam
Dmf: ENGLISH A(SR) C 72 . Dmf
Hla:ENGLISH A(SR) C __ Hla
Hla:ENGLISH C(SR) C __ Hla
Ils:ENGLISH A(SR) C 65 Ils
C
Ssi:ENGLISH A(SR)
Ssi:ENGLISH C(SR)
Thr: ENGLISH A(SR)
Thr:ENGLISH C(SR)
OTHER STOCKS
Hul:ABYSSINIAN C
Hul:PERWIAN C
non-designated C
68
68
Ssi
Ssi
Thr
Thr
Hul
Hul
Drb
non-designated C 58 Thr
[1inebred-various
colors]
OCR for page 9
9
RODENTS
GUINEA PIGS (Cavia porcellus) Inbred
Microbio- Surgical
Strain logical Present Modifications
Designation Status F Number Available Code
WRIGHT STRAIN 2
COBS~2/Crl BR -- Crl
2/Crc C 9 Crc
2/Elm§ C -- adr, hyp, ova, Elm
thy
WRIGHT STRAIN 13
COBS@13/Crl BR -- Crl
13/Crc C 51 Crc
COBRA is a registered trademark of The Charles River Breeding Labor-
atories, Inc., Wilmington, Massachusetts.
§These guinea pigs now are being outbred, but in 1978 were found to be
histocompatible with inbred Strain 2 animals from a number of other
sources.
GUINEA PIGS (Cavia porce77 us) Partially Inbred
Microbio- Number of
Stock logical Generations
Designation Status of Inbreeding Code
Emr:(HA)
Emr
OCR for page 10
10
RODENTS
HAMSTERS Outbred
Microbio- Colony
Stock logical Closed
Designation Status 19-- Comments Code
-
ARMENIAN OR GREY (ARM)
Iebs:(ARM)
(Cricetulus migratorius )
C 64
CHINESE OR STRIPED-BACK (CHN) (Cricetulus griseus)
prone to autoimmune
diseases;
free of spontaneous
neoplasms;
highly sensitive to low
doses of chemical car-
cinogens;
life span 1000 days
Iebs
Chi:(CHN) C 64 Chi
Iebs:(CHN)
~ 67
SYRIAN GOLDEN (SYR) (Mesocricetus auratus)
low incidence of span- Iebs
taneous neoplasms;
model for adjuvant-
induced lymphomatoid
& sarcomatoid granulo-
matosis, sarcoidosis,
vasculitis, pancrea-
titis, & insulitis;
life span 1000 days
Anp:(SYR) C __ Anp
Bbh:(SYR) [albino] C 77 Bbh
Bbh:(SYR) [various C 77 Bbh
colors]
Chi:(SYR) C 59 Chi
Eng:ELA(SYR) BR 68 Eng
Haf:(SYR) C 69 Haf
Haf:(SYR) [albino] C 65 Haf
Haf:(SYR) [black] C 75 Haf
OCR for page 11
11
RODENTS
HAMSTERS Outbred
Microbio-. Colony
Stock logical Closed
Designation Status 19-- Comments Code
SYRIAN GOLDEN ~ SYR) (Mesocricetus auratus) - cont.
Lak:LVG(SYR) C 51
surgical modifications: Lak
adr, cas, hyp, ova,
thy
Mcr:(SYR) C __ Mcr
Roc:(SYR) C __ Roc
Sas:(SYR) C 73 Sas
Sch:(SYR) BR 71 Sch
Sim:(SYR) C 76 Sim
Ssi:(SYR)f [outbred C
and linebred]
__
Ssi
OCR for page 30
30
RODENTS
RATS (Rattus norvegicus ) Outbred
Microbio- Colony Surgical
Stock logical Closed Modifications
Designation Status 19-- Available Code
BUFFALO ( BUF )
Mlr:(BUF)
BR --
HOLTZMAN SPRAGUE-DAWLEY~) H ( SD ) *
Crl:COES~CD@H(SD) BR, DF,
GF
Mlr
75 adr, cas, hyp, Crl
ova, thy
Hot:H(SD) C __ Hot
Sas:H(SD) C 66 Sas
LONG EVANS ( LE )
Blu:(LE) BR 64 adr, cas, hyp, Blu
ova, thr
Can:COBS@(LE) BR 71 adr, cas, hyp, Can
ova, thy
Haf:(LE) C 70 Haf
Mar:MFL(LE) BR 63 adr, cas, hyp, Mar
ova, thy, Grollman
modification
Mlr:(LE) BR -- cas Mlr
Pep:(LE) C 65 Pep
Roc:(LE) C __ Roc
Sim:(LE) BR 49 adr, cas, hyp, Sim
ova, pan, thy
*
Sprague-Dawley~ is a registered trademark of The Mogul Corporation,
Chagrin Falls, Ohio.
COBS~ and CD~ are registered trademarks of The Charles River Breeding
Laboratories, Inc., Wilmington, Massachusetts.
OCR for page 31
31
RODENTS
RATS (Rattus norvegicus ) Outbred
Microbio- Colony Surgical
Stock logical Closed Modifications
Designation Status 19-- Available Code
MUNICH WISTAR MUN(WI)
Tex:MUN(WI)~ BR, DF 76
GF, GN
OSBORNE MENDEL (OM)
Tex
Cam: (OM) C 53 adr, cas, hyp, Cam
ova, pan, thy,
parabiosis
Roc: (OM) C __ Roc
SHERMAN (SH)
BTU: (SH) BR 73 adr, cas, hyp, Blu
ova, thr
Cam: (SH) C 53 adr, cas, hyp, Cam
ova, pan, thy,
parabiosis
Roc: (SH) C __ Roc
SPONTANEOUSLY HYPERTENSIVE (SHR)
Tac:N(SHR)f BR -- adr, cas, hyp, Tac
ova, pan, thy,
others
SPRAGUE-DAWLEY(~(SD)*
Anp:(SD) C __ Anp
Bil: (SD) C 67 cas, ova Bil
Sprague-Dawley~ is a registered trademark of The Mogul Corporation,
Chagrin Falls, Ohio.
OCR for page 32
32
RODENTS
RATS (Rattus norvegicus) Outbred
Microbio- Colony Surgical
Stock logical Closed Modifications
Designation Status 19-- Available Code
S P RAGU E - DAWL KY(~) ~ SD ~ * - con
~t.
Blu:(SD) BR 54 adr, cas, hyp, Blu
ova, thr
Cam:(SD)f BR, DF 76 adr, cas, hyp, Cam
GF, GN ova, pan, thy,
parabiosis
Can: COBS~CD@(SD) BR 70 adr, cas, hyp, Can
ova, thy
Crl:COBS~CD~(SD) BR, DF, 50 adr, cas, hyp, Crl
GF ova, thy
Dub:(SD) C 70 adr, cas, ova, Dub
pan, thy
Fab:(SD)'' C __ adr, cas, ova Fab
Haf:(SD) C 67 Haf
Hap:(SD)f BR, DF, 75 adr, cas, hyp, Hap
GF, GN nep, ova, pare,
tier, thy
Hla:(SD) BR 72 Hla
Kng:(SD) BR 77 Kng
Lai:COX(SD) BR, DF, 67 Lai
GF
Mac:ML(SD)§ C 58 Mac
*
Sprague-Dawley~ is a registered trademark of The Mogul Corporation,
Chagrin Falls, Ohio.
COBS~ and CD~ are registered trademarks of The Charles River Breeding
Laboratories, Inc., Wilmington, Massachusetts.
11
Timed and untimed pregnant females available.
§ Mackesey Laboratories (Mac) accepts standing orders only.
OCR for page 33
RODENTS
RATS (Rattus norvegicus ) Outbred
Microbio- Colony Surgical
Stock logical Closed Modifications
Designation Status 19-- Available Code
SPRAGUE-DAWLEY(~) (SD )* - cont.
Mar:MFS(SD)1l BR 77 adr, cas, hyp, Mar
ova, thy, Grollman
modification
Mcr:(SD) C __ Mcr
Pep:(SD) C 65 Pep
Roc:(SD) C __ Roc
Saf:(SD) BR 66 Saf
Sas:(SD) DF 79 Sas
Sch: SPRAGUE- BR, GF 29 Sch
DAWLEY~(SD)
Sim:(SD)f BR, DF, 58 adr, cas, hyp, Sim
GN ova, pan, thy
Spb:(SD) C 63 cas, ova, thy Spb
Suo:(SD) C S4 Suo
Tac:N(SD)f BR -- adr, cas, hyp, Tac
ova, pan, thy,
others
Tex:(SD)f BR, DF, 69 Tex
GF, GN
Zml:ZM(SD)f§ BR 67 adr, cas, hyp, Zml
ova, pan, thy,
others
Sprague-Dawley~ is a registered trademark of The Mogul Corporation,
Chagrin Falls, Ohio.
.
.
Timed and untimed pregnant females available. Arrangements can
be made for animals to be held up to 24 months of age.
§Timed pregnant females and animals over 18 months of age available.
OCR for page 34
34
RODENTS
RATS (Rattus norvegicus) Outbred
Microbio- Colony Surgical
Stock logical Closed Modifications
Designation Status 19-- Available Code
~ _
l~lISTAR (hlI )
Anp:(WI) C __ Anp
Cam:(WI) C 64 adr, cas, hyp, Cam
ova, pan, thy,
parabiosis
Can:COBS~(WI) BR 74 adr, cas, hyp, Can
ova, pan, thy
Crl:COBS@(WI) BR, DF, 75 adr, cas, hyp, Crl
GF ova, thy
Fab:(WI)'' C __ adr, cas, ova Fab
Hap:(WI)f BR, DF, 46 adr, cas, hyp, Hap
GF, GN nep, ova, pare,
tier, thy
Hla:(WI) BR 56 Hla
Lai:COX(WI) BR, DF, 69 Lai
GF
Mar:MFW(WI) 11§ BR 72 adr, cas, hyp, Mar
ova, thy, Grollman
modification
Pep:(WI)
Roc:(WI)
Roy:(WI)
69
Pep
Roc
Roy
Sim:(WI) BR 57 adr, cas, hyp, Sim
ova, pan, thy
** fii'
COBSV is a registered trademark of The Charles River Breeding Labora-
tories, Inc., Wilmington, Massachusetts.
~1
Timed and untimed pregnant females available.
§ Arrangements can be made for animals to be held up to 24 months of age.
OCR for page 35
35
RODENTS
RATS (Rattus norvegic7~s) Outbred
Microbio- Colony Surgical
Stock logical Closed Modifications
Designation Status 19-- Available Code
hlISTAR (WI ) - cont.
Wbs:(WI) [linebred] C 74 Wbs
WISTAR KYOTO (Lilly ) @
Tac:N(WKY)f BR -- adr, cas, hyp,
ova, pan, thy,
others
@Control animals for Spontaneously Hypertensive (SHR) rats.
OCR for page 36
Strain
36
RODENTS
RATS (,Rattu5 norvegicusj Partially Inbred
Microbio- Number of Surgical
Modifications
logical Generations
Designation Status
of Inbreeding
Available Code
LONG EVANS ( LE )
Mlr:(LE) BR 8 cas Mlr
SPRAGUE-DAhlLEY(g) (SD)
Mlr:(SD) BR 8 cas Mlr
Sprague-Dawley~ is a registered trademark of The Mogul Corporation,
Chagrin Falls, Ohio.
OCR for page 37
37
RODENTS
RATS (Rattus norvegicus) Inbred
Microbio- Surgical
Strain logical Present Modifications
Designation Status F Number Available Code
ACI
ACI/Sim
BRO1~IN NORWAY ( BN )
c
ACI/Cox BR, DF, 100 Lai
GF
ACI/Hapf BR, DF, 5 adr, cas, hyp, Hap
GN nep, ova, pare,
tier, thy
ACI/Maif BR 98 Mai
32 adr, cas, hyp, Sim
ova, pan, thy
BN/Maif BR 41 Mai
BUFFALO ( BUF )
BUF/Cox BR, DF, 96 Lai
GF
BUF/Maif BR 76 Mai
BUF/Sim
47 adr, cas, hyp, Sim
ova, pan, thy
BUF/Texf BR, DF, 10-15 Tex
GF, GN
FISCHER 344 (F344)
COBS~CDF@F344/Crl BR, DF, 22 adr, cas, hyp, Crl
GF ova, thy
COBS~ and CDF~ are registered trademarks of The Charles River Breed-
ing Laboratories, Inc., Wilmington, Massachusetts.
OCR for page 38
38
RODENTS
RATS (Rattus norvegicus) Inbred
Microbio- Surgical
Strain logical Present Modifications
Desiqnation Status F Number Available Code
FISCHER 344 (F344) - cont.
F344/Cox BR, DF, 128 Lai
GF
F344/Hapf BR, DF, 3 adr, cas, hyp, Hap
GF, GN nep, ova, pare,
tier, thy
F344/Maif BR 112 Mai
F344/Sch BR, 26 Sch
GF, GN
F344/Simf BR 41 adr, cas, hyp, Sim
ova, pan, thy
GENETICALLY HYPERTENSIVE (GH)
GH/Zml BR 20+ adr, cas, hyp, ~ml
ova, pan, thy,
others
LEWIS (LEW)
COBS~LEW/Crl BR, DF, 52 adr, cas, hyp, Crl
GF ova, thy
LEW/Maif BR 79 Mai
MAXX
MAXX/Maif BR 28 Mai
COB S~ is a registered trademark of The Charles River Breeding Labora-
tories, Inc., Wilmington, Massachusetts.
OCR for page 39
39
RODENTS
RATS (Rattus norvegicus) Inbred
Microbio- Surgical
Strain logical Present Modifications
Designation Status F Number Available Code
SPONTANEOUSLY HYPERTENSIVE (SHR)
COBS@SHR/NCrl BR, DF, adr, cas, hyp, Crl
GF ova, thy
SHR/Cox BR, DF 41 Lai
GF
SPRAGUE-DAWLEY~ (SD)
MLSI(SD)/Mac§ C 80 Mac
WISTAR FURTH (WF)
WF/Maif BR 62 Mai
WF/Schf BR, 29 Sch
GF, GN
WISTAR KYOTO (WKY)@
COBS ~ Y/NCrl BR, DF, adr, cas, hyp, Crl
GF ova, thy
WKY/Cox BR, DF, 15 Lai
GF
Sprague-Dawley~ is a registered trademark of The Mogul Corporation,
Chagrin Falls, Ohio.
COB S~ is a registered trademark of The Charles River Breeding Labora-
tories, Inc., Wilmington, Massachusetts.
§ Mackesey Laboratories (Mac) accepts standing orders only
.
@ Control an~mals for Spontaneously Hypertensive (SHR) rats.
OCR for page 40
40
RODENTS
RATS (Rattus norvegicus ) Hybri d
Hybrid Microbiological
Designation Status Parental Strains Code
LBNF1 BR LEW/Mai x BN/Mai Mai
RATS (Rattus norvegicus ) Mutant
Microbio- &rgical
logical Modifications
Mutant Designation Status Available Code
j (Jaundice or Gunn) BR
fa (Fatty or Zucker)
C
di (Diabetes insipidus BR
or Brattleboro)
GH
(Genetically See inbred rat listing.
hypertensive)
SHR (Spontaneously
hypertensive)
adr, cas, hyp, Blu
ova, thr
adr, cas, hyp, Fab
pan, thy
adr, cas, hyp, Blu
ova
See inbred and outbred rat listings.
Representative terms from entire chapter:
available code
