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MALARIA: Obstacles and Opportunities
concept is to use those portions of the organism that are immunogenic, leaving out those that produce pathologic manifestations.
synthetic vaccine
a vaccine manufactured by biochemical means, to simulate the immunogenic portions of the organism against which the vaccine is being prepared.
tandem repeats
duplications of tandem combinations.
T lymphocyte
same as T cell. An immunologically competent white blood cell that direct the production of antibody by B lymphocytes; are responsible for cell-mediated immunity and immunological memory.
trophozoite
the stage, between the ring stage and the schizont, that occurs in the red blood cell.
tubulin
a principal protein component of microtubules (which play key roles in cell division and morphogenesis). Alpha- and beta-tubulins have been described.
vector
the mosquito that transmits the malaria parasite from one host to another.
vector competence
refers to the relative ability of a vector (relative to another vector) to transmit a specific infective agent from one host to another, implying that a competent vector is one that takes in sufficient numbers of an agent to ensure infection, supports the development or multiplication of the agent, and is able to deliver a large enough inoculum to an appropriate site in a new host to ensure infection.
vivax malaria
malaria caused by the malaria parasite Plasmodium vivax.