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generally, it recognizes, nevertheless, that opportunities may
exist for informative experiments in human populations that take
advantage of the possibility of using alternative schedules for
administration of vaccines.
A careful review is needed to identify what sorts of questions
might be best answered by further investigations and which kinds of
studies could be carried out economically. The availability and
introduction of new forms of pertussis vaccine, for example, could
offer valuable opportunities for comparison of vaccine safety as
well as efficacy. The committee is not in a position to make
specific recommendations, but its experience points to fresh
possibilities and to the need for such a review.