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Box 2-6
Investigations of Variola Virus at Vector (2000 to 2006)

Research studies of the genomic structure of different variola virus strains were carried out. Also of interest was the identification of potential antiviral drugs that might hold promise for the treatment of smallpox. These studies were generally successful despite delays in the approval processes in the two countries to initiate and continue activities, problems involved in delivery of funds to the researchers, difficulties encountered in exchange of reagents, and interruptions of effective communications between the Centers for Disease Control and Prevention and Vector. Cooperation on specific research projects ended in 2007. Still, the projects provided important research data for the international community and had a significant impact by establishing lasting ties among researchers from the two countries.

SOURCE: Personal observations of committee members of activities from 2000 to 2006, 2011.

BOX 2-7
Collaboration in Research on Brucellosis

For several years, U.S. agencies supported research on vaccines that would counter the spread of brucellosis through cattle and other herds in Russia. Also of concern was the infection of bison herds in the United States. Progress was made in limiting the spread of the disease through improvement of the vaccination procedures in Russia. Comparative research studies identified the most promising Russian and American brucella vaccines for prophylaxis in cattle as well as in wild animals.

SOURCE: Former Scientific Adviser for DOD programs, February, 2012.

appreciative of these opportunities to stay abreast of important international developments of direct relevance to their research interests. For their part, the Russian investigators quickly improved the content and quality of their scientific presentations at the conferences as they became accustomed to participation in such international gatherings.

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