Research Progress on Environmental, Health, and Safety Aspects of Engineered Nanomaterials (2013)

Below is the uncorrected machine-read text of this chapter, intended to provide our own search engines and external engines with highly rich, chapter-representative searchable text of each book. Because it is UNCORRECTED material, please consider the following text as a useful but insufficient proxy for the authoritative book pages.

Appendix A Biographic Information on the Committee to Develop A Research Strategy For Environmental, Health, and Safety Aspects of Engineered Nanomaterials JONATHAN M. SAMET (Chair) is a pulmonary physician and epidemiolo- gist. He is a professor and Flora L. Thornton Chair of the Department of Preven- tive Medicine of the Keck School of Medicine of the University of Southern California (USC) and director of the USC Institute for Global Health. Dr. Samet’s research has focused on the health risks posed by inhaled pollutants. He has served on numerous committees concerned with public health: the U.S. En- vironmental Protection Agency Science Advisory Board; committees of the Na- tional Research Council, including chairing the Committee on Biological Effects of Ionizing Radiation VI, the Committee on Research Priorities for Airborne Particulate Matter, and the Board on Environmental Studies and Toxicology; and committees of the Institute of Medicine (IOM). He is a member of IOM. Dr. Samet received his MD from the University of Rochester School of Medicine and Dentistry. JURRON BRADLEY joined BASF as a clean energy market manager in June 2011. In this role, he is responsible for creating BASF's first market facing-unit for the clean energy industry. Before joining BASF, Jurron led the consulting team at Lux Research, which provides clients with strategic advice on technology, includ- ing nanotechnology, and market trends and themes. Before joining Lux Research, Dr. Bradley worked at Praxair, Inc., where he designed air separation and argon recycling plants and managed a thermodynamics laboratory. He also led research efforts to reduce mercury emissions from coal-fired boilers and worked on the development of technology to reduce emissions of nitrogen oxides from coal-fired boilers. Dr. Bradley later joined Praxair’s technology planning and strategy group 126 

Appendix A 127 in which he played a key role in developing strategic approaches for the entire research and development organization. Dr. Bradley received a PhD in chemical engineering from the Georgia Institute of Technology. SETH COE-SULLIVAN is a cofounder and chief technology officer of QD Vi- sion. His work spans quantum dot materials; new fabrication techniques, including thin-film deposition equipment design; and device architectures for efficient QD- LED light emission. Dr. Coe-Sullivan has more than 20 papers and patents pend- ing in the fields of organic light-emitting devices, quantum dot LEDs, and nano- technology fabrication. He was awarded Technology Review magazine’s TR35 Award in 2006 as one of the top 35 innovators under the age of 35 years. In 2007, BusinessWeek named him one of the top young entrepreneurs under the age of 30 years, and in 2009, he was a finalist for the Mass Technology Leadership Coun- cil’s CTO of the year. Dr. Coe-Sullivan serves on Brown University’s Engineering Advisory Council. He received his PhD in electrical engineering from the Massa- chusetts Institute of Technology; his thesis work on incorporating quantum dots into hybrid organic-inorganic LED structures led to the formation of QD Vision. VICKI L. COLVIN is vice provost for research, professor of chemistry, and di- rector of the Center for Biological and Environmental Nanotechnology (CBEN) at Rice University. Among CBEN's primary interests is the application of nanotech- nology to the environment. She has received numerous accolades for her teaching abilities, including Phi Beta Kappa's Teaching Prize for 1998-1999 and the Ca- mille Dreyfus Teacher Scholar Award in 2002. In 2002, she was also named one of Discover magazine's Top 20 Scientists to Watch and received an Alfred P. Sloan Fellowship. In 2007, she was named a fellow of the American Association for the Advancement of Science (AAAS). Dr. Colvin is a frequent contributor to Advanced Materials, Physical Review Letters, and other peer-reviewed journals and holds patents to seven inventions. Dr. Colvin served on the NRC Committee for Review of the Federal Strategy to Address Environmental, Health, and Safety Research Needs for Engineered Nanoscale Materials. She received her PhD in chemistry from the University of California, Berkeley, where she was awarded the American Chemical Society’s Victor K. LaMer Award for her work in colloid and surface chemistry. EDWARD D. CRANDALL is the Hastings Professor and Kenneth T. Norris, Jr. Chair of Medicine and chair of the Division of Pulmonary and Critical Care Medi- cine of the Keck School of Medicine of the University of Southern California. Dr. Crandall’s clinical interests include critical-care medicine and pulmonary disease. He has written numerous peer-reviewed articles on cardiopulmonary biology. His specific research interests are in the regulation of the differentiation and transport properties of alveolar epithelial cells. He is actively involved in research on the interactions of nanomaterials with alveolar epithelium. Dr. Crandall received his PhD from Northwestern University and his MD from the University of Pennsyl- vania. 

128 Research Progress on EHS Aspects of Engineered Nanomaterials RICHARD A. DENISON is a senior scientist at the Environmental Defense Fund. Dr. Denison has 28 years of experience in the environmental arena, spe- cializing in chemical policy and hazards, exposure, and risk assessment and management of industrial chemicals and nanomaterials. He has testified before Congress numerous times on the need for fundamental reform of US policy to- ward industrial chemicals and on nanomaterial safety research needs. Dr. Den- ison is a member of the NRC Standing Committee on Emerging Science for Environmental Health Decisions and until recently served on the NRC Board on Environmental Studies and Toxicology. He serves on the Green Ribbon Science Panel for California’s Green Chemistry Initiative, and was a member of the Na- tional Pollution Prevention and Toxics Advisory Committee, which advised the Environmental Protection Agency’s Office of Pollution Prevention and Toxics. He was a member of EDF’s team that worked jointly with the DuPont Corpora- tion to develop a framework governing responsible development, production, use, and disposal of nanoscale materials. Previously, Dr. Denison was an analyst and assistant project director in the Oceans and Environment Program of the Office of Technology Assessment of the U.S. Congress. Dr. Denison received his PhD in molecular biophysics and biochemistry from Yale University. WILLIAM H. FARLAND is the senior vice president for research of Colorado State University and a professor in its Department of Environmental and Radio- logical Health Sciences in the School of Veterinary Medicine and Biomedical Sciences. In 2006, Dr. Farland was appointed deputy assistant administrator for science in the Environmental Protection Agency (EPA) Office of Research and Development (ORD). He had served as the acting deputy assistant administrator since 2001. In 2003, Dr. Farland has also been chief scientist in the Office of the Agency Science Adviser. He served as EPA's acting science adviser throughout 2005. Formerly, he was the director of ORD National Center for Environmental Assessment. Dr. Farland served on a number of executive-level committees and advisory boards in the federal government. In 2005-2006, he chaired the Execu- tive Committee of the National Toxicology Program. He was also a member of the Scientific Advisory Council of the Risk Sciences and Public Policy Institute of the Johns Hopkins University School of Hygiene and Public Health, a public member of the American Chemistry Council's Strategic Science Team for its Long-Range Research Initiative, and a member of the Programme Advisory Committee for the World Health Organization's International Programme on Chemical Safety. Dr. Farland recently served as chair of an external advisory group for the National Institute of Environmental Health Sciences regarding the future of the Superfund Basic Research Program. He is the chair of a standing Committee on Emerging Science for Environmental Health Decisions of the National Research Council. In 2002, Dr. Farland was recognized by the Society for Risk Analysis with the Outstanding Risk Practitioner Award, and in 2005, he was named a fellow of the society. In 2006, he received a Presidential Rank Award for his service as a federal senior executive. In 2007, he was elected a 

Appendix A 129 fellow of the Academy of Toxicological Sciences. Dr. Farland received his PhD from the University of California, Los Angeles in cell biology and biochemistry. MARTIN FRITTS is an emeritus researcher at SAIC-Frederick, Frederick Na- tional Laboratory for Cancer Research (FNLCR), and a research associate in the Materials Measurement Laboratory at the National Institute of Standards and Technology (NIST). Dr. Fritts supported SAIC-Frederick in implementing the National Cancer Institute's Cancer Nanotechnology Plan and the establishment of the Nanotechnology Characterization Laboratory at the FNLCR, and he works with NIST in their programs in nanotechnology, informatics, and the Ma- terials Genome Initiative. His primary interests are in the development of ad- vanced imaging and measurement instrumentation, modeling, and simulation to elucidate structure-activity relationships of nanomaterials in biologic environ- ments, and informatics systems to aid in improving data quality and advance knowledge-sharing. Dr. Fritts also serves as the cochair of the American Socie- ty for Testing and Materials’ E56.02 Subcommittee on Nanotechnology Charac- terization, and is a member of American National Standards Institute's US Tech- nical Advisory Group for ISO/TC 229, Nanotechnologies. Before joining SAIC- Frederick, he developed and prototyped nanotechnology applications for indus- try and government through SAIC's Nanotechnology Initiatives Division. His previous experience includes work in computational physics with the Naval Re- search Laboratory and with SAIC on computational fluid dynamics, simulation- based design, ship design, and nuclear fusion. His work has emphasized collab- oration in science and its translation to applications in industry, academia, and government. Dr. Fritts earned a PhD in nuclear physics from Yale University. PHILIP K. HOPKE is the Bayard D. Clarkson Distinguished Professor in the Department of Chemical and Biomolecular Engineering and the Department of Chemistry of Clarkson University. He is also director of the university’s Center for the Environment and its Center for Air Resources Engineering and Sciences. His research interests are related primarily to particles in the air, including parti- cle formation, sampling and analysis, composition, and origin. His current pro- jects are related to receptor modeling, ambient monitoring, and nucleation. Dr. Hopke has been elected to membership in the International Statistics Institute and is a fellow of the American Association for the Advancement of Science. He is also a fellow of the American Association for Aerosol Research, in which he has served in various roles, including president, vice president, and member of the board of directors. Dr. Hopke is a member of the American Institute of Chemical Engineers, the International Society of Exposure Science, and the In- ternational Society of Indoor Air Quality and Climate, and others. He has served as a member of the U.S. Environmental Protection Agency Advisory Council on Clean Air Act Compliance Analysis and as a member of several National Re- search Council committees, most recently the Committee on Energy Futures and Air Pollution in Urban China and the United States, the Committee on Research Priorities for Airborne Particulate Matter, and the Committee on Air Quality 

130 Research Progress on EHS Aspects of Engineered Nanomaterials Management in the United States. Dr. Hopke received his PhD in chemistry from Princeton University. JAMES E. HUTCHISON is the Lokey-Harrington Professor of Chemistry at the University of Oregon. He is the founding director of the Oregon Nanosci- ence and Microtechnologies Institute for Safer Nanomaterials and Nanomanu- facturing Initiative, a virtual center that unites 30 principal investigators in the Northwest around the goals of designing greener nanomaterials and nanomanu- facturing. Dr. Hutchison’s research focuses on molecular-level design and syn- thesis of functional surface coatings and nanomaterials for a wide array of appli- cations, in which the design of new processes and materials draws heavily on the principles of green chemistry. Dr. Hutchison received several awards and hon- ors, including the Alfred P. Sloan Research Fellowship and the National Science Foundation CAREER Award. He was a member of the National Research Council Committee on Grand Challenges for Sustainability in the Chemistry Industry. Dr. Hutchison received his PhD in organic chemistry from Stanford University. REBECCA D. KLAPER is an associate professor in the School of Freshwater Sciences, University of Wisconsin-Milwaukee. The School of Freshwater Sci- ences (at the Great Lakes WATER Institute) is dedicated to providing basic and applied research to inform policy decisions involving freshwater resources. Dr. Klaper uses traditional toxicologic methods and genomic technologies to study the potential effects of emerging contaminants, such as nanoparticles and phar- maceuticals, on aquatic organisms. Dr. Klaper received an American Associa- tion for the Advancement of Science and Technology Policy Fellowship, in which she worked in the National Center for Environmental Assessment at the Environmental Protection Agency (EPA). She has served as an invited scientific expert to both the U.S. National Nanotechnology Initiative and the Organisation for Economic and Co-operative Development Panel on Nanotechnology, for which she has testified on the potential effects of nanoparticles on the environ- ment and the utility of current testing strategies. She has served as a technical expert in reviewing the EPA white paper on the environmental effects of nano- technologies and the EPA research strategy for nanotechnology. She also was involved in writing the EPA white paper on the use of genomic technologies in risk assessment. Dr. Klaper received her PhD in ecology from the Institute of Ecology of the University of Georgia. GREGORY V. LOWRY is a professor in the Department of Civil and Envi- ronmental Engineering of Carnegie Mellon University and deputy director of the National Science Foundation Center for Environmental Implications of Nano- technology. He researches sustainable development of nanomaterials and nano- technologies, including the fate, mobility, and toxicity of nanomaterials in the environment, remediation and treatment technologies that use nanomaterials, and nanoparticle-contaminant and biota interactions. He also works on sustaina- 

Appendix A 131 ble energy via carbon capture and storage. His current projects include elucidat- ing the role of adsorbed macromolecules on nanoparticle transport and fate in the environment, in situ sediment management with innovative sediment caps, dense nonaqueous-phase liquid source zone remediation through delivery of reactive nanoparticles to the nonaqueous-phase-water interface, and carbon di- oxide capture, sequestration, and monitoring. Dr. Lowry served as an external advisory board member for the Center for Biological and Environmental Nano- technology. He was a review panelist for the Environmental Protection Agency draft nanomaterial research strategy. He is a member of the American Chemical Society, the American Society of Civil Engineers, and the Association of Envi- ronmental Engineering and Science Professors. He received his PhD in civil- environmental engineering from Stanford University. ANDREW D. MAYNARD is the director of the Risk Science Center of the University of Michigan School of Public Health. He previously served as the chief science adviser in the Woodrow Wilson International Center for Scholars for the Project on Emerging Nanotechnologies. Dr. Maynard’s research interests revolve around aerosol characterization, the implications of nanotechnology for human health and the environment, and managing the challenges and opportuni- ties of emerging technologies. Dr. Maynard’s expertise covers many facets of risk science, emerging technologies, science policy, and communication. Previ- ously, he worked for the National Institute for Occupational Safety and Health and represented the agency on the Nanomaterial Science, Engineering and Technology (NSET) subcommittee of the National Science and Technology Council and cochaired the Nanotechnology Health and Environment Implica- tions working group of NSET. He serves on the World Economic Forum Global Agenda Council on Emerging Technologies and is a member of the Executive Committee of the International Council on Nanotechnology. He previously chaired the International Standards Organization Working Group on size- selective sampling in the workplace. Dr. Maynard served as a member of the NRC Committee for Review of the Federal Strategy to Address Environmental, Health, and Safety Research Needs for Engineered Nanoscale Materials. He earned his PhD in aerosol physics from the Cavendish Laboratory of the Univer- sity of Cambridge, UK. GÜNTER OBERDÖRSTER is a professor in the Department of Environmen- tal Medicine of the University of Rochester, director of the University of Roch- ester Ultrafine Particle Center, principal investigator of a Multidisciplinary Re- search Initiative in Nanotoxicology, and head of the Pulmonary Core of the National Institute of Environmental Health Sciences Center Grant. His research includes the effects and underlying mechanisms of lung injury induced by in- haled nonfibrous and fibrous particles, including extrapolation modeling and risk assessment. His studies with ultrafine particles influenced the field of inha- lation toxicology, raising awareness of the unique biokinetics and toxic potential of nano-sized particles. He has served on many national and international com- 

132 Research Progress on EHS Aspects of Engineered Nanomaterials mittees and is the recipient of several scientific awards. Dr. Oberdörster has served on several National Research Council committees, including the Com- mittee on Research Priorities for Airborne Particulate Matter and the Committee on the Review of the Federal Strategy to Address Environmental, Health, and Safety Research Needs for Engineered Nanoscale Materials. He is on the edito- rial boards of the Journal of Aerosol Medicine, Particle and Fibre Toxicology, Nanotoxicology, and the International Journal of Hygiene and Environmental Health and is associate editor of Inhalation Toxicology and Environmental Health Perspectives. He earned his DVM and PhD (in pharmacology) from the University of Giessen, Germany. KATHLEEN M. REST is the executive director of the Union of Concerned Scientists (UCS), a science-based nonprofit. She manages the organization's day-to-day affairs, supervising programs on issues ranging from climate change and clean energy to global security. Dr. Rest came to UCS from the National Institute for Occupational Safety and Health (NIOSH) in the Centers for Disease Control and Prevention, where she was the deputy director for programs. Throughout her tenure at NIOSH, she held several leadership positions, includ- ing serving as the institute's acting director during the period of September 11, 2001, and the anthrax events that followed. Before her federal service, Dr. Rest served on the faculty of several medical schools—most recently as an associate professor in the Department of Family and Community Medicine of the Univer- sity of Massachusetts Medical Center and an adjunct associate professor in the University of Massachusetts School of Public Health—where she taught occupa- tional, environmental, and public health. She has extensive experience as a re- searcher and adviser on occupational and environmental health issues in various countries, such as the Netherlands, Slovakia, Poland, Romania, Canada, and Greece. Dr. Rest was a founding member of the Association of Occupational and Environmental Clinics, a national nonprofit organization committed to im- proving the practice of occupational and environmental health through infor- mation-sharing and collaborative research. She also served as the chairperson of the National Advisory Committee on Occupational Safety and Health. Dr. Rest earned her PhD in health policy from Boston University. MARK J. UTELL is a professor of medicine and environmental medicine, a director of occupational and environmental medicine, and former director of pulmonary and critical-care medicine in the University of Rochester Medical Center. He serves as associate chairman of the Department of Environmental Medicine. His research interests have centered on the effects of environmental toxicants on the human respiratory tract. Dr. Utell has published extensively on the health effects of inhaled gases, particles, and fibers in the workplace and other indoor and outdoor environments. He is the co-principal investigator of an Environmental Protection Agency (EPA) Particulate Matter Center and chair of the Health Effects Institute’s Research Committee. He has served as chair of EPA’s Environmental Health Committee and on the Executive Committee of the 

Appendix A 133 EPA Science Advisory Board. He is a former recipient of the National Institute of Environmental Health Sciences Academic Award in Environmental and Oc- cupational Medicine. Dr. Utell is currently a member of the National Research Council’s Board on Environmental Studies and Toxicology. He previously served on the National Research Council Committee on Research Priorities for Airborne Particulate Matter, the Institute of Medicine (IOM) Committee to Re- view the Health Consequences of Service during the Persian Gulf War, and the IOM Committee on Biodefense Analysis and Countermeasures. He received his MD from Tufts University School of Medicine. DAVID B. WARHEIT received his PhD in physiology from Wayne State Uni- versity School of Medicine in Detroit. Later, he received a National Institutes of Health (NIH) postdoctoral fellowship, and 2 years later, a Parker Francis Pul- monary Fellowship, both of which he took to the National Institute of Environ- mental Health Sciences to study mechanisms of asbestos-related lung disease with Arnold Brody. In 1984, he moved to the DuPont Haskell Laboratory to develop a pulmonary-toxicology research laboratory. His major research inter- ests are pulmonary toxicity mechanisms and corresponding risks related to in- haled particles, fibers, and nanomaterials. He is the author or coauthor of more than 100 publications and has been the recipient of the International Life Sci- ences Institute (ILSI) Kenneth Morgareidge Award (1993, Hannover, Germany) for contributions in toxicology by a young investigator and the Robert A. Scala Award and Lectureship in Toxicology (2000). He has also attained diplomate status of the Academy of Toxicological Sciences (2000) and the American Board of Toxicology (1988). He has served on NIH review committees (NIH Small Business Innovation Research and NIH Bioengineering) and has partici- pated in working groups of the International Agency for Research on Cancer, the European Centre for Ecotoxicology and Toxicology of Chemicals, Organisa- tion for Economic Co-operation and Development, the ILSI Risk Science Insti- tute, the ILSI Health and Environmental Sciences Institute, and the National Research Council. He has served on several journal editorial boards, including Inhalation Toxicology and Toxicological Sciences (as the current associate edi- tor), Particle and Fibre Toxicology, Toxicology Letters, and Nano Letters. He is the chairman of the European Centre for Ecotoxicology and Toxicology of Chemicals Task Force on Health and Environmental Safety of Nanomaterials, serves on the National Institute for Occupational Safety and Health Board of Scientific Counselors, and is interim vice-president of the Nanotoxicology Spe- cialty Section. MARK R. WIESNER serves as director of the Center for the Environmental Implications of Nanotechnology, headquartered at Duke University, where he holds the James L. Meriam Chair in Civil and Environmental Engineering with appointments in the Pratt School of Engineering and the Nicholas School of Environment. Dr. Wiesner’s research has focused on the applications of emerg- ing nanomaterials to membrane science and water treatment and an examination 

134 Research Progress on EHS Aspects of Engineered Nanomaterials of the fate, transport, and effects of nanomaterials in the environment. He was coeditor and author of Environmental Nanotechnologies and serves as associate editor of the journals Nanotoxicology and Environmental Engineering Science. Before joining the Duke University faculty in 2006, Dr.Wiesner was a member of the Rice University faculty for 18 years, where he held appointments in the Department of Civil and Environmental Engineering and the Department of Chemical Engineering and served as associate dean of engineering and director of the Environmental and Energy Systems Institute. Before working in academe, Dr. Wiesner was a research engineer with the French company Lyonnaise des Eaux, in Le Pecq, France, and a principal engineer with the environmental engi- neering consulting firm of Malcolm Pirnie, Inc., White Plains, NY. He received the1995 Rudolf Hering Medal from the American Society of Civil Engineers, of which he is a fellow, and the 2004 Frontiers in Research Award from the Asso- ciation of Environmental Engineering and Science Professors, on whose board he serves. In 2004, Dr. Wiesner was also named a de Fermat Laureate and was awarded an International Chair of Excellence in the Chemical Engineering La- boratory of the French Polytechnic Institute and National Institute for Applied Sciences in Toulouse, France. He received his PhD in environmental engineer- ing from the Johns Hopkins University.