FIGURE H-11 Quanterix Simoa HD-1 analyzer.
All of the systems presented have the capability to meet the majority of the autonomous detection system requirements. The most significant challenge will be the ability to provide sufficient specificity for organism discrimination. A clear example of this is that a Food and Drug Administration–approved antibody-based test for Bacillus anthracis, sold by Tetracore, Inc., uses the harmless vaccine strain for a positive control. This challenge may be overcome by the speed in which these technologies provide information to the customer community.
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"Appendix H: White Paper 3: State of the Art for Autonomous Detection Systems Using Immunoassays and Protein Signatures."
Technologies to Enable Autonomous Detection for BioWatch: Ensuring Timely and Accurate Information for Public Health Officials : Workshop Summary.
Washington, DC: The National Academies Press, 2014.
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