Serology

the discipline concerned with the immunologic study of body fluids

Serum

the liquid that separates from blood after coagulation

Sex chromosomes (x and y chromosomes)

chromosomes that are different in the two sexes and that are involved in sex determination

Sex-linked characteristic

a genetic characteristic, such as color blindness, that is determined by a gene on a sex chromosome and shows a different pattern of inheritance in males and females; X-linked is a more specific term

Single-locus probe

a DNA probe that detects genetic variation at only one site in the genome; an autoradiogram that uses one single-locus probe usually displays one band in homozygotes and two bands in heterozygotes

Somatic cells

the differentiated cells that make up the body tissues of multicellular plants and animals

Southern blot

the nylon membrane to which DNA adheres after the process of Southern blotting

Southern blotting

the technique for transferring DNA fragments that have been separated by electrophoresis from the gel to a nylon membrane

Standards

criteria established for quality control and quality assurance; established or known test reagents, such as molecular-weight standards


T

single-letter designation of the pyrimidine base thymine; also used in diagrams to represent a nucleotide containing thymine

Tandem repeats

multiple copies of an identical DNA sequence arranged in direct succession in a particular region of a chromosome

Taq polymerase

a DNA polymerase used to form double-stranded DNA from nucleotides and a single-stranded DNA template in the PCR technique

Thymine

a pyrimidine base; one of the four nitrogen-containing molecules present in nucleic acids DNA and RNA; designated by the letter T


Uracil

a pyrimidine in RNA


Variable number of tandem repeats (VNTR)

repeating units of a DNA sequence for which the number varies between individuals

VNTR

variable number of tandem repeats


Zygote

diploid cell that results from the fusion of male and female gametes



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