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• Prematurity (≤37 weeks' gestational age)a
• Very low birth weight (less than 1,500 g)a
• Low birth weight (less than 2,500 g)a
• Congenital anomalies of the gastrointestinal, renal, hepatic, cardiovascular, and central nervous systems
• Oral-facial anomalies, e.g., cleft palate
• Some congenital syndromes and genetic disorders, e.g., cystic fibrosis and Down syndrome
• Inborn errors of metabolism, e.g., phenylketonuria (PKU), galactosemia, or maple sugar urine disease (MSUD)
• Necrotizing enterocolitis
• Excessive or intractable diarrhea or vomiting
• Respiratory distress or apnea
• Chronic lung disease (bronchopulmonary dysplasia)
• Maternal diabetes mellitus
• Drug withdrawal
• Sepsis, peritonitis, meningitis
• Perinatal hypoxia
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