Bronchoconstriction.

Narrowing of a bronchus caused by contraction of bronchial smooth muscle.

Bronchoprovocation test.

An aerosolized solution of the test allergen is delivered by inhalation through a dosimeter in graded increasing dosages. The response is measured by spirometry.

Bronchospastic.

Constriction of the bronchi due to smooth muscle contraction and edema and resulting in asthma.

Bronchus.

One of the large conducting air passages of the lung.

Byssinosis.

An occupational respiratory disease associated with the inhalation of cotton, flax, or hemp dust. It is characterized initially by chest tightness, shortness of breath, and cough but may lead to permanent lung damage.

C

Carcinogen.

A cancer-causing substance or agent.

Cell-mediated immunity (CMI).

Those manifestations of the immune reaction that are characterized by a cellular response, in particular by T lymphocytes and macrophages.

Colony-forming units.

The number of colonies on an agar plate (petri dish) after culturing.

Contact sensitization.

To stimulate an immune response upon initial skin contact with an antigen, with the consequence of preparing the body for a repeat response upon reexposure to the antigen.

Coprophagia.

Feeding on dung.

Cross-reactivity of antigens.

The interaction of an antigen with an antibody formed against a different antigen with which the first antigen shares closely related or common antigenic determinants. The effect is to reduce the specificity and sensitivity of the test method.

Cytokine.

A substance produced by cells, including T cells, that transmits messages between cells to control and modulate immune responses.

Cytotoxic.

Lethal to cells.

D

Delayed-type hypersensitivity.

An inflammatory reaction that occurs 24 to 48 hours after challenge with an antigen and that is a result of lymphocyte-mediated immunity.

Dermatitis.

An inflammatory skin condition.

Dermatographism.

Urticaria due to physical allergy, in which moderately firm stroking or scratching of the skin with a dull instrument produces a pale, raised welt or wheal, with a red flare on each side.

Dermatophagoides pteronyssinus.

A common cosmopolitan sarcoptiform mite commonly found in house dust accumulations and thought to be a contributory cause of atopic house dust asthma.

Dew point temperature.

The temperature at which moist air becomes



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