systems;

Maintenance of buildings;

Sick building syndrome

C

Carpeting, 19, 24, 38, 213-214, 223, 230

and cat dander, 101

and dust mites, 10, 16, 95, 96

and rhinitis, 37

Case control studies, 59

Cat dander, 9, 99-102

and HVAC filters, 14

lions and tigers, 105

reagents for, 11, 25, 100, 106

Cattle, 104-105

CD4+ cells, 136, 139, 147

Cell-mediated immunity, 132

and dermatitis, 73

and fungi, 26-27

testing of, 12, 53, 166, 168

Cellular processes and mechanisms, 135-144

Central heating, see Heating;

HVAC systems

Chemical allergens, 9, 27-28, 117-125

exposure assessment, 32

and in vitro testing, 30

multiple chemical sensitivity, 43

and rhinitis, 27, 119, 121

sensitization to, 27, 28, 53, 122-123

Chicago, asthma, 70

Children, 44, 47, 56, 57, 98

asthma education, 233-236

asthma onset, 67, 68

asthma prevalence, 6, 59, 61, 64, 69, 70

bronchial hyperreactivity, 180

bronchitis, 59

dermatitis, 73

dust mite sensitization, 50, 51

rhinitis, 72

Chronic obstructive pulmonary disease (COPD), 79-81

Classification of reactions, 3, 39, 40, 132

Cockroaches, 9, 91-92

Colds, 83

Competing risks, 59-60

Condensation, 211-212, 227

Conjunctivitis, 3, 132

and chemical allergens, 13, 119, 121

Construction materials, 214

Contact dermatitis, 73-74

Control measures

cat dander, 101-102

for dust mites, 9, 10, 24, 94-96, 225-226, 236-238

efficacy assessment, 17-18, 24, 44, 98

fungal and microbial infestation, 97, 114-116

household, 7, 9, 10, 98

insects, 96-97

pets and animals, 26, 96, 104, 107

pollen, 97

and quality of life, 24, 98-99

research needs, 23-24, 98

see also Education;

Engineering control;

Therapeutic interventions

Costs

analyses, 15-16, 84

asthma cases, 7, 22, 34-35, 61, 84

Cotton dust standard, 176

Cromolyn, 10

Cross-reactivity, 11, 30, 31, 91, 166, 169-170

Cultural environment

and allergy prevalence, 22, 84

and asthma, 70

Cumulative exposure, 13

Cystic fibrosis

and allergic bronchopulmonary aspergillosis, 74

Cytokines, 147, 149-150, 168

D

Daily diaries, 159-160

Dander, see Cat dander

Deaths, asthma, 6, 8, 34, 64, 65-67, 70

Deer, 105

Definition of allergy, 39

Dehumidifiers, 212, 227

Front Matter (R1-R11)

Executive Summary (1-33)

1 Introduction (34-43)

2 Magnitude and Dimensions of Sensitization and Disease Caused by Indoor Allergens (44-85)

3 Agents, Sources, Source Controls, and Diseases (86-130)

4 Mechanisms of Immune Function (131-152)

5 Medical Testing Methods (153-184)

6 Assessing Exposure and Risk (185-205)

7 Engineering Control Strategies (206-232)

8 The Role of Education (233-245)

References (246-280)

Acronyms (281-283)

Glossary (284-292)

Committee and Staff Biographies (293-298)

Index (299-308)