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Veterans at Risk: The Health Effects of Mustard Gas and Lewisite (1993)
Institute of Medicine (IOM)

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. "3 History and Analysis of Mustard Agent and Lewisite Research Programs in the United States." Veterans at Risk: The Health Effects of Mustard Gas and Lewisite. Washington, DC: The National Academies Press, 1993.

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Veterans at Risk: The Health Effects of Mustard Gas and Lewisite

TABLE 3-2 Known Gas Testing Facilities and Test Typesa

Location  

Type of Experiments

Edgewood Arsenal, Maryland  

Chamber and patch tests Small-scale field tests Gas production

Bainbridge, Maryland

Chamber tests

Dugway Proving Ground, Utah  

Large-scale field tests

Camp Sibert, Alabama  

Chamber and patch tests (1943-1944 only)

Naval Research Laboratory, Virginia  

Chamber and patch tests

Great Lakes Naval Training Center, Illinois  

Chamber and patch tests

Camp Lejeune, North Carolina  

Chamber tests

San Jose Island, Canal Zone  

Large-scale field tests Chamber tests

Bushnell, Florida

Large-scale field tests

Other Allied Tests  

Finschhafen, New Guinea

Large-scale field tests

Innisfail, Australia

Large-scale field tests Chamber tests

Porton Down, England

Chamber tests (reported) Patch tests (reported)

a This represents only a partial list of locations, especially for patch tests because patch exposures were a frequent part of training at Chemical Warfare Schools. In addition, British testing reports are still classified and not. available

SOURCES: Cochrane, 1946; Gillis, 1985; Office of Scientific Research and Development, 1946.

TABLE 3-3 Concentration Versus Cumulative Exposure Level: Explanation of Notations in NRL Reports and Modern Literature

Concentration

γ/La

Used in NRL reports to signify micrograms (µg, also called gamma) per liter (1, according to modern notation) or µg/l

mg/m3

milligrams per cubic meter, equivalent to µg/l

ppm

parts per million, a volume to volume measurement that, at 25°C at sea level, is equal to 6.5 mg/m3 of sulfur mustard

Cumulative Exposure

CT

Used in NRL reports to signify concentration (C) multiplied by time (T); equal to mg·min/m3, modern notation uses t to signify time (Ct)

a The use of L to signify liters is confusing because L is also the abbreviation for Lewisite. However, used with micrograms in the NRL reports, L signified liters.

SOURCE: Taylor et al., 1943.

summarizes the various notations used in NRL reports, along with other sources, to express concentrations, and compares these with modern notation. In addition, this table illustrates the difference between atmospheric concentration and the concept of cumulative exposure, in which

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Front Matter (R1-R20)
Executive Summary (1-8)
1 Introduction (9-13)
2 Methods of Literature Collection and Survey (14-20)
3 History and Analysis of Mustard Agent and Lewisite Research Programs in the United States (21-60)
4 Findings from the Public Hearing Process (61-70)
5 Chemistry of Sulfur Mustard and Lewisite (71-80)
6 Relationship of Mustard Agent and Lewisite Exposure to Carcinogenesis (81-111)
7 Nonmalignant Respiratory Effects of Mustard Agents and Lewisite (112-130)
8 Ocular Effects of Mustard Agents and Lewisite (131-147)
9 Dermatological Effects of Mustard Agents and Lewisite (148-178)
10 Other Physiological Effects of Mustard Agents and Lewisite (179-198)
11 Relationship of Mustard Agent and Lewisite Exposure to Psychological Dysfunction (199-213)
12 Summary of Findings and Recommendations (214-226)
Bibliography (227-330)
A. Scientific and Background Presentations Made to the Committee (331-334)
B. Excerpt from The Residual Effects of Warfare Gases (335-337)
C. Involvement of the National Academy of Sciences Complex in World War II Research Programs: A Summary (338-339)
D. Excerpts from Chamber Tests with Human Subjects I, II, and IX. Naval Research Laboratory Reports Nos. P-2208 and P-2579 (340-369)
E. Interim Report and Addendum: Feasibility of Developing a Cohort of Veterans Exposed to Mustard Gas During WWII Testing Programs (370-377)
F. Summary of the Department of the Army Report: Use of Volunteers in Chemical Agent Research (378-381)
G. Public Hearing Announcement (382-385)
H. Letter from Dr. Jay Katz to Dr. David P. Rall (386-389)
I. Risk Assessment Considerations for Sulfur Mustard (390-398)
J. Examination of the Effects of Certain Acute Environmental Exposures on Future Respiratory Health Consequences (399-416)
List of Acronyms and Abbreviations (417-420)
Index (421-428)