Robert L. Dedrick, National Cancer Institute. Toxicology Lessons from Cancer Chemotherapy.

David H. Wegman, University of Massachusetts. Examination of the Effects of Certain Acute Environmental Exposures on Future Respiratory Health Consequences.

O. Michael Colvin, Johns Hopkins University School of Medicine. Nitrogen Mustard Therapy and Second Cancers.

James M. Melius, State of New York Department of Health. The Bhopal Disaster.

Han K. Kang, Department of Veterans Affairs. Feasibility of Developing a Cohort of Veterans Exposed to Mustard Gas During WWII Testing Programs.

Richard Solana, United States Army Medical Research Institute of Chemical Defense. Toxicology of Lewisite.

Peter Sandman, Rutgers University. Communicating Risk.

Jay Katz, Yale University. Informed Consent: History, Development, and Application to Special Populations.

Front Matter (R1-R20)

Executive Summary (1-8)

1 Introduction (9-13)

2 Methods of Literature Collection and Survey (14-20)

3 History and Analysis of Mustard Agent and Lewisite Research Programs in the United States (21-60)

4 Findings from the Public Hearing Process (61-70)

5 Chemistry of Sulfur Mustard and Lewisite (71-80)

6 Relationship of Mustard Agent and Lewisite Exposure to Carcinogenesis (81-111)

7 Nonmalignant Respiratory Effects of Mustard Agents and Lewisite (112-130)

8 Ocular Effects of Mustard Agents and Lewisite (131-147)

9 Dermatological Effects of Mustard Agents and Lewisite (148-178)

10 Other Physiological Effects of Mustard Agents and Lewisite (179-198)

11 Relationship of Mustard Agent and Lewisite Exposure to Psychological Dysfunction (199-213)

12 Summary of Findings and Recommendations (214-226)

Bibliography (227-330)

A. Scientific and Background Presentations Made to the Committee (331-334)

B. Excerpt from The Residual Effects of Warfare Gases (335-337)

C. Involvement of the National Academy of Sciences Complex in World War II Research Programs: A Summary (338-339)

D. Excerpts from Chamber Tests with Human Subjects I, II, and IX. Naval Research Laboratory Reports Nos. P-2208 and P-2579 (340-369)

E. Interim Report and Addendum: Feasibility of Developing a Cohort of Veterans Exposed to Mustard Gas During WWII Testing Programs (370-377)

F. Summary of the Department of the Army Report: Use of Volunteers in Chemical Agent Research (378-381)

G. Public Hearing Announcement (382-385)

H. Letter from Dr. Jay Katz to Dr. David P. Rall (386-389)

I. Risk Assessment Considerations for Sulfur Mustard (390-398)

J. Examination of the Effects of Certain Acute Environmental Exposures on Future Respiratory Health Consequences (399-416)

List of Acronyms and Abbreviations (417-420)

Index (421-428)