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Responsible Science: Ensuring the Integrity of the Research Process, Volume II
§2Orientation of BTRC Research Personnel
§2.1 BTRC personnel receive a brochure describing the BTRC research and publication policies and procedures recommended in these guidelines, as well as the School of Medicine, University of California, San Francisco, Guidelines to Promote Ethical Conduct in Research (Appendix A[2.1]), and the Uniform Requirements for Manuscripts Submitted to Biomedical Journals (URM) (Appendix B[2.1]).1
The BTRC brochure includes a directory to sources of information about, e.g., animal care, radioisotope usage, human experimentation requirements, biohazard safety, and statistical support (Appendix C[2.1]).2
§2.2 Fellows and residents beginning work in the BTRC attend an orientation consisting of two 90-minute sessions sponsored by the BTRC. This program provides an overview of the research and publication processes in the BTRC and the resources available to the BTRC research group. Faculty attend the program at least once to familiarize themselves with and provide suggestions related to the information it contains.
§3.1 Data Management and Review
In general, two primary forms of data records are maintained in each BTRC laboratory: the methodology notebook and the experimental notebook. Laboratories with several investigators and/or research projects keep a laboratory master log. A data selection file containing data selected for publication and documents related to publication is kept for each paper resulting from a study. BTRC standards for accurate collection and recording of data and for storing data are detailed in §4 of these guidelines.
§3.1.1 The PI has final responsibility for the validity of the data.
§3.1.2 The PI has final responsibility for maintaining methodology notebooks and laboratory master logs relevant to the PI's laboratory and for seeing to it that those books