|
Items in cart [0] |
Questions? Call 888-624-8373 |
PAPERBACK PDF BOOK Free Resources |
||||||||||||||||
|
||||||||||||||||
|
||||||||||||||||
| ||||||||||||||||||||||||||||||
|
||||||||||||||||||||||||||||||
| Copyright © 2009. National Academy of Sciences. All rights reserved. Terms of Use and Privacy Statement |
Below are the first 10 and last 10 pages of uncorrected machine-read text (when available) of this chapter, followed by the top 30 algorithmically extracted key phrases from the chapter as a whole.
Intended to provide our own search engines and external engines with highly rich, chapter-representative searchable text on the opening pages of each chapter.
Because it is UNCORRECTED material, please consider the following text as a useful but insufficient proxy for the authoritative book pages.
Do not use for reproduction, copying, pasting, or reading; exclusively for search engines.
OCR for page 133
Index
Acromegaly, 94, 96
Addison's disease (hyperadrenocorticism),
93, 95-96
Adenovirus, 54-57
Adipose tissue, 26
Aging, 79-81
Alaria cants, 62
Albumin, 106
Alpha-2 agonists, 67
Amebas, 58, 59
American College of Veterinary
Ophthalmologists, 115
American Veterinary Medical Association
(AVMA) Panel on Euthanasia, 70-71
Ameroid, 88-89
Analgesics
anti-inflammatory nonsteroidal, 67
euthanasia, 70-71
opioid, 66-67
pain alleviation, 63-68
postsurgical, 68-69
Ancylostoma spp., 44, 59-61
Anemia, 100
Anesthesia and anesthetics
alleviation of pain, 64-68
Anestrus, 41, 81
Angiotensin-converting enzyme (ACE), 87-
88, 91
Animal Welfare Act, 1, 11
Animal Welfare Regulations (AWRs)
cross referenced, 131 - 132
defined, 1-2
Antigens, 5, 120
Antibiotics, 69
Arthritis, 5, 79
Artificial insemination, 37-39
Ascarids (Toxocara cants; Toxascaris
leonina), 58-60
Association of American Feed Control
Officials, 24, 42
Attachment formation, 44-45
Auscultation, 85
Autoimmune diseases, see Immunologic
diseases; and specific diseases
Autoimmune hemolytic anemia, 102- 104
Autoimmune (lymphocytic) thyroiditis, 102-
104
Babesia spp., 62-63
euthanasia, 70-71 Babesiosis, 62-63
gene therapy, 120, 122 Bacterial diseases, see specific diseases
general, 64-66, 69
inhalants, 64, 71
injectable drugs, 64-65, 70-71
local, 66
hypothermia, 17
neuromuscular blocking agents, 65-66
presurgical, 69
133
Balantidium spp., 58-59
Barbiturates, 70
Bedding and resting apparatus, 11, 26-27,
30, 113
Behavior
aging, 79
aggressive, 5, 23, 30, 45-46, 67, 70
blindness and ocular pain, 115- 116
OCR for page 134
34
fearful, 23, 45-46, 53, 67-68
herding, 5
maladaptive, 22, 53, 67
necrologic disorders, 108- 109
record-keeping, 46
selection of experimental animals, 7-9
socialization, 7-9, 11, 22-24, 44-46, 53
see also Stressors and distress
Benzodiazepines, 67-68
Biohazards, 119
Bioimplants, 85
Bladder disorders, 81
Bleeding disorders, 99-101
Blindness, 114-115
Blood glucose monitoring, 94
Blood pressure, 89-90
Blood urea nitrogen (BUN), 89
Body size, 7, 25-26, 30
Body weight, 7, 25-26, 30, 39-40, 42-43, 67,
80, 95, 99, 117
Bone marrow transplantation, 107, 117, 120-
121
Bordetella bronchiseptica, 54-56
Breeding colonies
deworming, 43-44
infectious diseases, 40-41, 55-56
neonatal care, 39-47, 56
nutritional requirements, 42-43
record-keeping, 46-47
reproduction, 35-41, 83-84
socialization, 44-46
specific-pathogen-free, 57
vaccination, 43-44, 55-56
see also Specific-pathogen-free
animals; Reproduction; Vaccines
. . .
and vaccination
INDEX
Decapitation, 71
Degenerative joint disease, 79
Demodex cants, 58
Dental diseases, 25, 79-80, 100
Deoxycorticosterone acetate (DOCA), 88
Deworming, 43-44
Diabetes mellitus, 5, 94-95
Diarrhea, 59, 61
Diazepam, 67-68
Digoxin, 80-81
Dipylidium caninum, 62
Dirofilaria immitis, 5, 59, 61
Dirofilariasis, 5, 59, 61
Distemper, 5, 54-57
Distress, see Stressors and distress
DLA (major histocompatiblity complex), 5
Drainage, 14- 15
Drugs, see Analgesics; Anesthesia and
Anesthetics; Injectable drugs; and
specific drugs
Duchenne's muscular dystrophy, 110- 111
Dysesthesias, 113
Dystocia, 41-42
Ear mites (Otodectes cynotis), 58
Echinococcus spp., 62
Echocardiography, 85, 87
Ectoparasites, 57-58; see also Parasitic
diseases; and specific ectoparasites
Ehlers-Danlos syndrome, 12, 91-92
Ehrlichia cants, 62-63
Ehrlichiosis, 62-63
Electrocardiography, 69, 85, 87
Electrocution, 71
Embryo-transfer technology, 57
Emergency, weekend, and holiday care, 29
Endocrinologic diseases, 79, 93-97
clinical features, 93-94
husbandry and veterinary care, 94-97
Cages and pens, 19-20, 30-31 see also specific diseases
Calcium derangements, 93-97 Endoparasites, 44, 58-63; see also Parasitic
Carbon dioxide, 71 diseases; and specific endoparas~tes
Carbon monoxide, 71 Entamoeba spp., 59
Cardiovascular diseases, 5, 61, 70, 80-87;
see also Hypertension; and specific
diseases
Catheterization, 69, 85-87, 89, 113
Cheyletiella yasguri, 58
Chemoprophylaxis, 59, 61
Code of Federal Regulations, defined, 1-2
Colostrum, 43, 104
Common variable immunodeficiency, 102
104
Complement (C3) deficiency, 105-106
Complete blood counts (CBCs), 86-87
Congenital heart defects, 81-84
Conotruncal defects, 82
Cornification, 39
Cryptosporidium spp., 58-59
Cyanosis, 83-84
Cyclic hematopoiesis, 98, 100
Brucella cants, 37, 55
Brucellosis, 37, 55
Environmental controls, see environmental
conditions under Housing
Environmental enrichment, 11, 21-24
Enzyme-linked immunosorbent assay
(ELISA) kit, 37, 41
Erythrocyte phosphofructokinase deficiency,
98, 100-101
Esophageal nematode (Spirocerca lupi), 62
Estrus, 23, 30, 35-39, 41, 81, 95-96
Euthanasia
cardiac defects, 83, 86
ethics, 72
human considerations, 71-72
inhalation methods, 71
injection methods, 70
lysosomal storage diseases, 108-110
muscular dystrophy, 111-112
necropsy examination, 40
OCR for page 135
INDEX
physical methods, 71
radiation injury, 119
Exercise, see under Housing
Exsanguination, 71
Factor X deficiency, 98, 101
False estrus, 41
Fearful behavior, 23, 45-46, 53? 68
Filaroides spp., 58-59
Fleas, 58, 62
Food and nutrition
aging, 79-80
bleeding disorders, 99-100
body size, 25-26
body weight, 25-26, 43
cardiovascular diseases, 85
conditioning, 53
contaminants, 26
deprivation, 78
diabetes, 95-96
feeding programs, 25-26
hypertension, 90-91
labels, 24
lysosomal storage diseases, 109- 110
muscular dystrophy, 111
neonatal, 42-43
necrologic diseases, 113
nutritional content, 24-25
organ transplantation, 107
orthopedic diseases, 117
pregnancy and lactation, 42
restraint training, 78
transportation, 29-31
Forms, 28-29
Fucosidosis, 108-109
Gases, 19, 31
Gene therapy, 79, 119- 122
Genetic factors, and selection of
experimental animals, 5-7, 79
Genetic mapping, 5-6
Geriatrics, 79-81
Geriatrics and Gerontology, 81
Giardia spp., 58-59
Glucocorticosteroids, 117
Good Laboratory Practice Standards, 2
Granulocytopathy, 102- 104
Granulomatous pneumonia, 111
Growth hormones, 96, 102- 104
Guide for the Care and Use of Laboratory
Animals (Guide), defined, 1-2
Hair-follicle mites (D emodex cants), 5 8
Hazards, and selection of experimental
animals, 5
Health Research Extension Act of 1985, 1
Hearing loss, 79
Heartworms (Dirofilaria immitis), 5, 59, 61
Helminths, 58-63
Hematologic diseases, 97-98
bleeding disorders, 99- 101
clinical features, 6, 97-98
135
cyclic hematopoiesis, 100
husbandry and veterinary care, 99
101
reproduction, 101
see also specific diseases
Hematopoietic stem cells, 120- 121
Hemophilia, 97, 101, 121
Hepatitis, 54-57
Herpesvirus, 54-56
Heterodoxus spiniger, 58
Hookworms (Ancylostoma spp.; Uncinaria
stenocephala), 44, 59-61
Housing
aging, 80
chemicals and toxic substances, 19
criteria for design and construction, 12
14
drainage, 14- 15
Ehlers-Danlos syndrome, 92
environmental conditions, 16- 19, 31,
44-46, 104
exercise, 11-12, 21-22, 83, 95, 111
hematologic diseases, 99- 101
holding areas, 31-32
hypertension, 91
immunodeficiency diseases, 104- 106
indoor facilities, 14- 15
lysosomal storage diseases, 109
muscular dystrophy, 111
necrologic diseases, 113
noise, 19, 39
necrologic diseases, 113
outdoor facilities, 14, 16
postoperative, 85
power and lighting, 18
primary enclosures, 19-20, 30-31
quarantine facilities, 54-55
radiation injury, 119
sheltered housing facilities, 14- 16
solitary, 22
space recommendations, 20-21
temperature and humidity, 16- 17, 31,
40, 80
ventilation, 17-19, 30-31, 119
whelping facilities, 39-40
Husbandry, see Bedding and resting
apparatus; Emergency, weekend,
and holiday care; Environmental
enrichment; Food and nutrition;
Housing; Identification and records;
Record-keeping; Sanitation; Water
and watering devices
Hyperadrenocorticism (Addison's disease),
93, 95-96
Hypercalcemia, 93-97
Hypertension, 87-91
Hypoadrenocorticism, 93-96
Hypocalcemia, 93-96
Hypothermia, 17, 26-27
Hypothyroidism, 93
Hypoxia, 71
OCR for page 136
136
IATA, see International Air Transport
Association
Identification and records, 11, 27-30
IgA deficiency, 102- 104
IgM deficiency, 102- 104
Immune thrombocytopenic purpura, 102- 104
Immunologic diseases
acquired, 102
autoimmune, 5, 101-105
clinical features, 6, 101-107
complement deficiency, 105- 106
husbandry and veterinary care, 104- 107
organ transplantation, 106- 107
primary immunodeficiency, 101 - 105
see also specific diseases
Immunoprophylaxis, 43
Inbreeding, 37
Induced heart defects, 84-87
Infectious diseases, 5, 53-57, 80; see also
specific pathogens and specific
d iseases
Inhalant anesthetics, see under Anesthesia
and anesthetics
Injectable drugs, 64-65, 70-71
Institutional animal care and use committee
(IACUC), 29, 76-78
Instrument implantation, 70
Instruments, artificial insemination, 38-39
Insulin, 94-95
Interleukin-6 dysregulation, 102- 105
International Air Transport Association
(IATA), 2, 31
Interstate and International Certificate of
Health Examination for Small
Animals (USDA), 29
Intestinal fluke (Alaria cants), 62
Isospora spp., 58-59
Kennel cough, 54-56
Leishmania spp., 62
Le ishmanias is , 62
Leptospirosis, 55-56
Lethal injection, 70-71
Lice (Linognathus setosus; Trichodectes
cants; Heterodoxus spiniger), 58
Linognathus setosus, 58
List of Licensed Dealers, 52
Lung diseases, 60, 80
Lung fluke (Paragonimus kellicotti), 61-62
Lysosomal storage diseases (LSDs), 6, 107-
110; see also specific diseases
Major histocompatibility complex (DLA), 5
Male-female ratio, 37
Mange (Sarcoptes scabei), 58
Mating, see Reproduction
Measles, 56
Metabolic bone diseases, 25, 43
Microsatellite probes, 6
Microsporum spp., 54
INDEX
Mites, 58
Mitotane, 95-96
Models, canine, 6
Monitoring, 17, 53
Motor deficits, 113
Mucopolysaccharidosis, 108- 110
Muscle mass, 26
Muscular dystrophy, 110- 112
Musculoskeletal diseases, 6
Mycoplasma spp., 54
Nasal mite (Pneumonyssoides caninum), 58
National Association of State Public Health
Veterinarians, 55
Nematodes, 59, 61-62
Neonatal care, see under Breeding colonies
Neurologic diseases, 5, 6, 112-114; see also
specific diseases
Neuromuscular blocking agents, 65-66
Neutropenia, 118
Nicotine, 71
Nitrous oxide, 64
Nutrition, see Food and nutrition
Ocular defense mechanisms, 115-116
Ocular pain, 114, 116
Oocysts, 59
Ophthalmologic diseases, 114-116; see also
specific diseases
Organ transplantation, 106-107
Orthopedic diseases, 5, 116- 117; see also
specific diseases
Otodectes cynotis, 58
Ownership transfer, 28
Packs, 7-8, 23
Pain, 63-67, 114, 116; see also Analgesics;
Anesthesia and anesthetics;
Stressors and distress; Surgery
Paragonimus kellicotti, 61-62
Parainfluenza, 54-56
Parasitic diseases, 5, 8-9. 37, 44, 55, 57-63;
see also specific parasites and
specific diseases
Particulate contaminants, 31
Parturition, see Reproduction
Parvovirus, 5, 54-56
Patent ductus arteriosus, 81-83
Pathogens, see Infectious diseases; and
specific pathogens
Pentatrichomonas spp., 59
Persistent truncus arteriosus, 82
·Pharmacologic therapy, 87
Phenothiazines, 67-68
Pheromones, 37
Photoperiod, and reproductive cycle, 36
Physaloptera spp., 62
Physical fitness and enclosure size, 20
Physiologic monitoring and testing, 53
fecal and blood tests for endoparasites,
63
OCR for page 137
INDEX
implantation of instruments, 70
inadequately socialized dogs, 45
induced heart defects, 85-86
pregnancy tests, 39-40
renal function in hypertensive dogs, 88-
89
surgical and postsurgical, 69
Pneumonyssoides caninum, 58
Polyps, 81
Pregnancy, see Reproduction
Procurement, 52-53
Prostatic disorders, 81
Proteinuria, 106
Protocol review, 76-78
Protozoa, 58-63
Pseudopregnancy, 41
Public Health Service Policy on Humane
Care and Use of Laboratory
Animals (PHS Policy), 1-2
Pulmonary valve dysplasia, 83
Purpose-bred animals, 52, 54, 57-61, 63, 68
Pyometra, 81
Pyruvate kinase deficiency, 98, 100
Quarantine facilities, 54-55
Rabies, 9, 54-56
Radiation injury, 117- 119
Radiation pneumonitis, 118
Radioactive-waste disposal, 118
Radiography, as pregnancy test, 39
Radionuclides, 118- 119
Random-source animals, 52-55, 57-58, 63
Record of Disposition of Dogs and Cats
(USDA), 29
Record of Dogs and Cats on Hand (USDA),
29
Record-keeping
animal-care staff, 28
federal regulations, 28-29
reproduction, 38, 46-47
Reinforcement techniques, 78
Renal diseases, 80, 87-89, 91, 106
Retinal degeneration, 6, 79, 88, 90-91
Reproduction
acromegaly, 96
aging, 81
anestrus, 41, 81
artificial insemination, 37-39
cardiovascular diseases, 83-84
Ehlers-Danlos syndrome, 92
estrus, 23, 30, 35-39 ,41, 81. 95-96
false estrus, 41
hematologic dieseases, 101
immunologic diseases, 105- 106
lysosomal storage diseases, 110
muscular dystrophy, 112
natural mating, 37-38
necrologic diseases, 114
ophthalmologic diseases, 116
137
orthopedic diseases, 117
pregnancy and parturition, 39-41, 114
pseudopregnancy, 41
radiation, 119
record-keeping, 38, 46-47
reproductive cycle, 35-37, 46, 81
semen, 38-39
see also Breeding colonies
Research protocols, 76-78
Respiratory diseases, 55, 113; see also
specific diseases
Restraint methods, 78
Restriction-fragment length polymorphisms
(RFLPs), 6
Rheumatoid arthritis, 102- 104
Rhipicephalus sanguineus, 57-58, 62
Ringworm (Microsporum spp.), 54
Roundworm (Toxocara cants), 44, 58-60
Sanitation, 14-15, 19, 26-27, 30, 58-63, 68-
69, 119
Sarcoptes scabei, 58
Scent-marking, 37
Semen, 38-39
Sensory deficits, 113
Septicemia, 102, 107
Serum creatinine concentration, 89
Serum urea nitrogen, 106
Severe combined immunodeficiency, 102-104
Sjogren's syndrome, 102- 104
Skin keratinocytes, 121
Smooth muscle transplantation, 121 - 122
Social contact and interaction, 7-9, 11, 22-
24, 44-46, 53, 117
Sodium-to-potassium ratio, 95-96
Specific-pathogen-free (SPF) animals, 57,
59-61, 63
Spirocerca lupi, 62
Spondylosis, 79
Sterilization, surgical instruments, 68-69
Stomach nematode (Physaloptera spp.), 62
Stressors and distress
allevation, 64-68
blindness, 115
blood-glucose response, 95
environmental, 21-22, 53, 67-68, 95-96
hypertension measurement, 90
non-pain-induced, 67-68
pain-induced, 63-64
parturition, 41
recognition, 63-64, 67
signs of pain, 64
sleep, 22
transportation, 29-30
treatment, 67-68
vocalization, 44-45, 63-64
see also Analgesics; Anesthesia and
anesthetics; Behavior; Pain; Surgery
Strongyloides stercoralis, 59-60
Strychnine, 71
Subaortic stenosis, 81-83
OCR for page 138
138
Surgery
cardiovascular diseases, 84-87
gene therapy, 120- 122
hypothermic recovering dogs, 17
pain, 63-67
postsurgical care, 69-70, 85, 91, 107
presurgical preparation, 68-69, 107
record-keeping, 28
renal failure, 89
see also Analgesics; Anesthesia and
anesthetics; Pain; Stressors and distress
Systemic lupus erythematosus, 102- 104
Taenia spp., 62
Tapeworms (Dipylidium caninum;
Echinococcus spp.; Taenia spp.), 62
Tattoos, 27-28
Testicular atrophy, 81
Tetralogy of Fallot, 82
Thrombocytopenia, 118
Thrombopathia, 98, 101
Thyrogastric disease, 102- 104
Thyroid atrophy, 79
Thyroiditis, 102- 104
Tick (Rhipicephalus sanguineus), 57-58, 62
Total-body irradiation (TBI), 107, 117, 119-
121
Total serum protein, 106
Toxascaris leonina, 58-60
Toxocara cants, 44, 58-60
Tracheobronchitis, 54-55
Tranquilizers, 66-68, 70; see also specific
tranquilizers
Transplantation studies, 57
Transponders, 28
Transportation
environmental conditions, 31
health certificates, 31-32
holding areas, 31-32
food and water, 29-31
primary enclosures, 30-31
stress, 29-30
Trichodectes cants, 58
Trichomonas spp., 59
Trichuris vulpis, 59, 61
Truncus arteriosus, persistent, 82
Trypanosoma cruzi, 62
Ultrasonography, 39
U.S. Department of Agriculture (USDA), 11,
21, 27-28, 32, 52
U.S. Government Principles for Utili7ation
and Care of Vertebrate Animals
Used in Testing, Research, and
Training, 63-64
Uncinaria stenocephala, 44, 59-61
INDEX
Vaccines and vaccination
animal-care personnel, 9, 62
bleeding disorders, 101
breeding colonies, 43-44, 55-56
development, 5, 57
hematologic disorders, 101
multivalent, 55-56
schedule for pups, 56
social and behavioral factors, 8-9, 78
Vaginal cytology, 36-37, 39, 81
Vasodilators, 91
Venipuncture, 7-9, 70, 78
Ventricular septal defects (VSDs), 82
Vermin, 13, 15-16, 18-19
Veterinary care
aging, 80-81
cardiovascular diseases, 83, 85-86
Ehlers-Danlos syndrome, 92
emergency, 29
endocrinologic diseases, 97
health certificates, 31-32
hematologic diseases, 99-101
immunologic diseases, 104- 107
infectious-disease control, 53-57
lysosomal storage diseases, 109- 110
muscular dystrophy, 111 - 112
neurologic diseases, 113
ophthalmologic diseases, 115
orthopedic diseases, 116- 117
pain and distress, 63-68
parasitic-disease control, 57-63
parturition, 40
procurement, 52-53
record-keeping, 28
surgery and postsurgical care, 68-70
see also Euthanasia; Surgery; Vaccines
and vaccination; and specific diseases
Viral diseases, see Infectious diseases; and
. r. 7.
spec~;zc a~seases
von Willebrand's disease, 97-98, 101
`'Walking dandruff" (Cheyletiella yasguri),
58
Warts, 54
Washing facilities, 15
Water and watering devices, 26-27, 29-31, 53,
78, 80, 95, 99, 109, 111, 113
Weaning, 42-43, 46
Well-being
definition and measurement, 21
exercise, 22
Whipworm (Trichuris vulpis), 59, 61
X rays, 118
xmd dogs, 110-112
Zoonoses, 8-9, 37, 55, 62
OCR for page 139
Representative terms from entire chapter:
lysosomal storage
