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NOTICE: The project that is the subject of this report was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine. The members of the committee responsible for the report were chosen for their special competences and with regard for appropriate balance.

This report has been reviewed by a group other than the authors according to procedures approved by a Report Review Committee consisting of members of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine.

The National Research Council established the Board on Mathematical Sciences in 1984. The objectives of the Board are to maintain awareness and active concern for the health of the mathematical sciences and to serve as the focal point in the National Research Council for issues connected with the mathematical sciences. The Board holds symposia and workshops and prepares reports on emerging issues and areas of research and education, conducts studies for federal agencies, and maintains liaison with the mathematical sciences communities, academia, professional societies, and industry.

Support for this project was provided by the Fondation des Treilles, Alfred P. Sloan Foundation, National Science Foundation, Department of Energy, and National Library of Medicine.

Library of Congress Cataloging-in-Publication Data

Calculating the secrets of life : applications of the mathematical
sciences in molecular biology/Eric S. Lander, editor.
p.  cm.
Includes bibliographical references and index.
ISBN 0-309-04886-9
1. Genetics -- Mathematical models. 2. Genetics -- Statistical
methods. 3. Molecular biology -- Mathematical models. 4. Molecular
biology -- Statistical methods. I. Lander, Eric S.
QH438.4.M3C35  1994
574.8'8'0151--dc20                                                        94-37628
        CIP

Copyright 1995 by the National Academy of Sciences. All rights reserved.

Printed in the United States of America.



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