1. No evidence bearing on a causal relation^c

Autism

2. Evidence insufficient to indicate a causal relation^d

Aseptic meningitis Chronic neurologic damage Erythema multiforme or other rash

Guillain-Barré syndrome

Hemolytic anemia

Juvenile diabetes

Learning disabilities and attention-deficit disorder

Peripheral mononeuropathy Thrombocytopenia

Radiculoneuritis and other neuropathies

Thrombocytopenic purpura

3. Evidence does not Indicate a causal relation^e

Infantile spasms

Hypsarrythmia

Reye syndrome

Sudden infant death syndrome

4. Evidence is consistent with a causal relation^f

Acute encephalopathy^g

Shock and "unusual shocklike state"

Chronic arthritis

^aEvidence does not differentiate between DPT vaccine and the pertussis component of DPT vaccine except in the case of protracted, inconsolable crying where the evidence implicates the pertussis component specifically.

^bRA 27/3 MMR, Trivalent measles-mumps-rubella vaccine containing the RA 27/3 rubella strain,

^cNo category of evidence was found bearing on a judgment about causation (all categories of evidence left blank in Table 1-1).

^dRelevant evidence in one or more categories was identified but was judged to be insufficient to indicate whether or not a causal relation exists (no category of evidence checked as supporting causation in Table 1-1; exceptions are this designation under biologic plausibility for erythema multiforme and hemolytic anemia).

^eThe available evidence, on balance, does not indicate a causal relation (one or more categories of evidence checked as not supporting causation in Table 1-1, with evidence supporting causation being either absent or outweighed by the other evidence).

^fThe available evidence, on balance, tends to support a causal relation (one or more categories of evidence checked as supporting causation in Table 1-1, with evidence checked as insufficient or not supporting causation being absent or outweighed by the other evidence).

^gDefined in controlled studies reviewed as encephalopathy, encephalitis, or encephalomyelitis.

^hThe available evidence, on balance, supports a causal relation, and the evidence is more persuasive than that for conclusion 4 above (the categories of evidence are coded similarly to thos in conclusion 4, with evidence checked as insufficient or not supporting causation in Table 1-1 being absent or less than for 4).