TABLE B-1 Vaccines and Adverse Events Studied

Adverse Event

T/D/Td

Measles

Mumps

OPV

IPV

Hib

Hep. B

Encephalopathy (acute and chronic)

X

X

X

 

 

 

 

Aseptic meningitis

 

 

X

X

 

 

 

Subacute sclerosing panencephalitis

 

X

 

 

 

 

 

Residual (chronic) seizure disorder

X

X

X

 

 

 

 

Guillain-Barré syndrome

X

X

 

X

X

X

X

Transverse myelitis

X

X

 

X

X

X

X

Paralytic poliomyelitis (in recipient or contact)

 

 

 

X

 

 

 

Myelitis

 

 

 

 

 

 

X

Neuropathy

X

 

X

 

 

 

 

Optic neuritis

 

X

 

 

 

 

 

Sensorineural deafness

 

X

X

 

 

 

 

Sterility via orchitis

 

X

X

 

 

 

 

Death

X

X

X

X

X

X

X

Anaphylaxis

X

X

X

 

X

X

X

Arthritis

X

 

 

 

 

 

X

Erythema multiforme

X

 

 

 

 

 

 

Insulin-dependent diabetes mellitus

 

X

X

 

 

 

 

Early susceptibility to Hib disease

 

 

 

 

 

X

 

Thrombocytopenia

 

X

X

 

X

X

 

NOTE: T/DT/Td, tetanus toxoid/diphtheria and tetanus toxoids for pediatric use/tetanus and diphtheria toxoids for adult use; OPV, oral polio vaccine; IPV, inactivated polio vaccine; Hib, Haemophilus influenzae type b vaccine; Hep. B, hepatitis B vaccine.



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