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Adverse Events Associated with Childhood Vaccines: Evidence Bearing on Casuality (1994)
Institute of Medicine (IOM)

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. "Index." Adverse Events Associated with Childhood Vaccines: Evidence Bearing on Casuality. Washington, DC: The National Academies Press, 1994.

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Adverse Events Associated with Childhood Vaccines: Evidence Bearing on Causality

Guillain-Barré syndrome, 87, 151, 216, 219, 244, 246

immunosuppression, 64

multiple sclerosis, 36, 220

neuropathy, 90-91

optic neuritis, 147-148

orchitis, 160-161, 163

poliomyelitis, 191

residual seizure disorder, 79, 142

sensorineural deafness, 146

subacute sclerosing panencephalitis, 136

thrombocytopenia, 164-165, 248

transverse myelitis, 149, 196, 199, 242

Brachial neuritis, 54-55

causality, 16, 93-94

diphtheria-tetanus vaccination and, 16, 90, 91, 92, 93-94

C

Campylobacter jejuni, 39

Canada, 131, 132, 144, 161, 166, 173

Case-control studies, 29

Case reports and uncontrolled studies, 5

absence of, 22

anaphylaxis, 104-108, 171-175, 229, 262

arthritis, 95-97, 224-226

aseptic meningitis, 131-134

brachial neuritis, 91-92

data sources, 23, 28-29

demyelinating diseases, 84-85, 221

diabetes mellitus, 156-158

early-onset Hib disease, 253-254, 256-260

encephalopathy, 74-75, 123-129

erythema multiforme, 98-99

evaluation of, 23-26

fatal outcomes, 275, 287-289, 291-294, 296-298, 300, 301

Guillain-Barré syndrome, 87-88

infantile spasms, 81

mononeuropathy, 91

multiple sclerosis, 221

optic neuritis, 85, 148, 221

orchitis, 161-162

poliomyelitis, 190, 191-194

residual seizure disorder, 79-81, 142-145

role of, 22

sensorineural deafness, 146

subacute sclerosing panencephalitis, 136-138

thrombocytopenia, 165-167, 248-249

transverse myelitis, 149-150, 198-199, 242

Causality

anaphylaxis, 16, 17, 108, 109, 110, 175-176, 205, 230-231, 262-263

arthritis/arthropathy, 97, 226-227

aseptic meningitis, 134-135

brachial neuritis, 16, 93-94

Can It? assessment, 20-23

categories of, 16-17, 32-33

combination vaccines, 5

definitions, 19-20

demyelinating diseases, 47-48, 85-86, 222

diabetes mellitus, 159

Did It? assessment, 20, 23-26

early-onset Hib disease, 260-261

encephalopathy, 16, 77-78, 129-130

erythema multiforme, 99

evidence for determination of, 5, 22-23, 27-33

fatal outcomes, 16, 17, 109-110, 205-206, 231, 263, 276-277, 277-278, 289-290, 294-295, 298-299, 300-301, 302

focal lesions, 36-37

Guillain-Barré syndrome, 16, 17, 88-89, 109, 110, 153, 203-204, 219 , 246

Haemophilus influenzae type b, 16, 17

infantile spasms, 16, 17, 82

Koch's postulates, 19

measles vaccine-strain viral infection, 17, 176-177, 291, 294-295

mononeuropathy, 54, 93, 94

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