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Veterans and Agent Orange: Health Effects of Herbicides Used in Vietnam (1994)
Institute of Medicine (IOM)

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. "7 Epidemiologic Studies." Veterans and Agent Orange: Health Effects of Herbicides Used in Vietnam. Washington, DC: The National Academies Press, 1994.

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Veterans and Agent Orange: Health Effects of Herbicides Used in Vietnam

TABLE 7-2 Epidemiologic Studies—Environmental Exposure

Reference

Study Design

Description

Study Group (N)

Comparison Group (N)a

Seveso

Boeri et al., 1978

Cohort

Evaluation of neurological disorders among Seveso residents exposed to TCDD on July 10, 1976, compared to residents in unexposed areas

470 zone A

152 zone R

Filippini et al., 1981

Cohort

Comparison of prevalence of peripheral neuropathy on two screening examinations among Seveso residents, compared to residents in unexposed areas

308

305

Barbieri et al., 1988

Cohort

Comparison of prevalence of peripheral nervous system involvement among Seveso residents with chloracne, compared to residents in unexposed areas

152

123

Bisanti et al., 1980

Descriptive

Descriptive report of selected health outcomes among residents of Seveso located in zones A, B, R

730 zone A;

4,737 zone B;

31,800 zone R

No comparison group

Caramaschi et al., 1981

Cohort

Evaluation of chloracne among children in Seveso, compared to children with no chloracne, and association with other health outcomes between chloracne and no chloracne groups

146

182

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376